电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

Muscarinic Acetylcholine Receptor M2 抗体 (C-Term)

CHRM2 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1108326
发货至: 中国
  • 抗原 See all Muscarinic Acetylcholine Receptor M2 (CHRM2) 抗体
    Muscarinic Acetylcholine Receptor M2 (CHRM2) (Cholinergic Receptor, Muscarinic 2 (CHRM2))
    抗原表位
    • 16
    • 15
    • 9
    • 8
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 451-466, C-Term
    适用
    • 90
    • 40
    • 37
    • 8
    • 8
    • 8
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    大鼠
    宿主
    • 79
    • 11
    • 2
    • 1
    克隆类型
    • 79
    • 14
    多克隆
    标记
    • 45
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This Muscarinic Acetylcholine Receptor M2 antibody is un-conjugated
    应用范围
    • 79
    • 34
    • 26
    • 26
    • 20
    • 18
    • 16
    • 11
    • 8
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    特异性
    This antibopdy detects Muscarinic acetylcholine receptor M2 (C-term). It shows no cross reactivity with other proteins.
    交叉反应 (详细)
    Species reactivity (tested):Rat
    纯化方法
    Immunogen affinity chromatography
    免疫原
    Synthetic peptide corresponding to a sequence at the C-terminal of human CHRM2 (451-466aa), identical to the related rat sequence
    亚型
    IgG
    Top Product
    Discover our top product CHRM2 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 溶解方式
    0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    缓冲液
    5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
    储存液
    Sodium azide, Thimerosal (Merthiolate)
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    Muscarinic Acetylcholine Receptor M2 (CHRM2) (Cholinergic Receptor, Muscarinic 2 (CHRM2))
    别名
    Muscarinic Acetylcholine Receptor M2 (CHRM2 产品)
    别名
    HM2 antibody, AChR-M2 antibody, Chrm-2 antibody, M2 antibody, chrm2 antibody, Acm2 antibody, GPM2 antibody, cholinergic receptor muscarinic 2 antibody, cholinergic receptor, muscarinic 2, cardiac antibody, cholinergic receptor, muscarinic 2a antibody, cholinergic receptor, muscarinic 2 antibody, CHRM2 antibody, Chrm2 antibody, chrm2a antibody
    背景
    The muscarinic acetylcholine receptor M2, also known as the cholinergic receptor, muscarinic 2, is a muscarinic acetylcholine receptor. The M2 muscarinic receptors are located in the heart, where they act to slow the heart rate down to normal sinus rhythm after stimulatory actions of the sympathetic nervous system, by slowing the speed of depolarization. The CHRM2 gene inhibits the release of acetylcholine from cholinergic fibers in the lungs and elsewhere. In airway parasympathetic neurons, it is decreased by viral infections and by interferon-gamma, increasing actylcholine release. This gene is thought to be involved in neuronal excitability, synaptic plasticity and feedback regulation of acetylcholine release and has previously been implicated in higher cognitive processing. In a sample of 667 individuals from 304 families, Gosso MF et al. genotyped three single-nucleotide polymorphisms (SNPs) in the CHRM2 gene on 7q31-35. CHRM2 is implicated in memory and cognition, functions impaired in many neuropsychiatric disorders.Synonyms: CHRM2, mAChR M2, mAChR-M2
    基因ID
    81645
    NCBI登录号
    NP_112278
    UniProt
    P10980
You are here:
客服