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MORG1 抗体 (N-Term)

wdr83 适用: 人, 大鼠, 小鼠 WB, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1108280
发货至: 中国
  • 抗原 See all MORG1 (wdr83) 抗体
    MORG1 (wdr83) (WD Repeat Domain 83 (wdr83))
    抗原表位
    • 15
    • 7
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 38
    • 34
    • 33
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 48
    • 5
    克隆类型
    • 51
    • 2
    多克隆
    标记
    • 21
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MORG1 antibody is un-conjugated
    应用范围
    • 38
    • 19
    • 13
    • 13
    • 9
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    特异性
    This antibody MORG1 detects (N-term). No cross reactivity with other proteins.
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse, rat
    纯化方法
    Immunogen affinity purified
    免疫原
    Synthetic peptide corresponding to a sequence near the N-terminal of human MORG1 .Remarks: Sequence is identical to the related mouse and rat sequence.
    亚型
    IgG
    Top Product
    Discover our top product wdr83 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 溶解方式
    0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    缓冲液
    5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
    储存液
    Sodium azide, Thimerosal (Merthiolate)
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    MORG1 (wdr83) (WD Repeat Domain 83 (wdr83))
    别名
    MORG1 (wdr83 产品)
    别名
    MORG1 antibody, 1500041N16Rik antibody, Morg1 antibody, RGD1306947 antibody, morg1 antibody, MAPK organizer 1 antibody, wu:fj29g04 antibody, zgc:92654 antibody, WD repeat domain 83 antibody, WD repeat domain containing 83 antibody, WD repeat domain 83 L homeolog antibody, WDR83 antibody, Wdr83 antibody, wdr83.L antibody, wdr83 antibody
    背景
    MORG1 (mitogen-activated protein kinase organizer 1), a member of the WD-40 protein family that was isolated as a binding partner of the extracellular signal-regulated kinase (ERK) pathway scaffold protein MP1. MORG1 specifically associates with several components of the ERK pathway, including MP1, Raf-1, MEK, and ERK, and stabilizes their assembly into an oligomeric complex. MORG1 facilitates ERK activation when cells are stimulated with lysophosphatidic acid, phorbol 12-myristate 13-acetate,or serum, but not in response to epidermal growth factor. Suppression of MORG1 by short interfering RNA leads to a marked reduction in ERK activity when cells are stimulated with serum. MORG1 is a component of a modular scaffold system that participates in the regulation of agonist-specific ERK signaling.Synonyms: MAPK organizer 1, MGC4238, Mitogen-activated protein kinase organizer 1
    基因ID
    84292
    NCBI登录号
    NP_001093207
    UniProt
    Q9BRX9
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