MMP8 抗体 (N-Term)
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- 抗原 See all MMP8 抗体
- MMP8 (Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MMP8 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects MMP-8. No cross reactivity with other proteins.
- 交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
- 纯化方法
- Immunogen affinity purified
- 免疫原
- A synthetic peptide corresponding to a sequence at the N-terminal of human MMP8 .Remarks: Sequence is different to the related rat sequence by three amino acids
- 亚型
- IgG
- Top Product
- Discover our top product MMP8 Primary Antibody
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anti-Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8) (AA 101-467) antibody
MMP8 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C8 unconjugated
anti-Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8) antibodyMMP8 适用: 人 WB, IHC (p), IP, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8) antibodyMMP8 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8) (AA 120-157), (N-Term) antibodyMMP8 适用: 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8) (AA 241-340) antibodyMMP8 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8) (AA 22-283) antibodyMMP8 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8) antibodyMMP8 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8) (AA 1-467) antibodyMMP8 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8) (AA 1-467) antibodyMMP8 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8) (C-Term) antibodyMMP8 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IHC (p), ICC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 溶解方式
- 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 缓冲液
- 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
- 储存液
- Sodium azide, Thimerosal (Merthiolate)
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- 抗原
- MMP8 (Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8))
- 别名
- MMP-8 (MMP8 产品)
- 别名
- MMP8 antibody, BB138268 antibody, CLG1 antibody, HNC antibody, MMP-8 antibody, PMNL-CL antibody, matrix metallopeptidase 8 antibody, neutrophil collagenase antibody, MMP8 antibody, Mmp8 antibody, LOC100339790 antibody
- 背景
- MMP8 (Matrix metalloproteinase 8) is a member of the family of matrix metalloproteinases. It is distinct from the collagenase of skin fibroblasts and synovial cells in substrate specificity and immunologic crossreactivity. MMP8 was mapped to 11q21-q22. MMP8 is an enzyme that degrades fibrillar collagens imparting strength to the fetal membranes, is expressed by leukocytes and chorionic cytotrophoblast cells. The enzyme exhibits 58 % homology to human fibroblast collagenase and has the same domain structure. It consists of a 20-residue signal peptide, and an 80-residue propeptide that is lost on autolytic activation by cleavage of an M-L bond. MMP8 was found to possess 57 % identity with the deduced protein sequence for fibroblast collagenase with 72 % chemical similarity. Matrix metalloproteinases (MMPs) have fundamental roles in tumor progression, but most clinical trials with MMP inhibitors have not shown improvements in individuals with cancer. MMP8 has a paradoxical protective role in cancer and provides a genetic model to evaluate the molecular basis of gender differences in cancer susceptibility.Synonyms: CLG1, MMP8, Matrix metalloproteinase-8, Neutrophil collagenase, PMNL collagenase, PMNL-CL
- 基因ID
- 4317
- NCBI登录号
- NP_002415
- UniProt
- P22894
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