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Lactoferrin 抗体

LTF 适用: 人 WB, EIA, IHC (fro) 宿主: 小鼠 Monoclonal 265-1K1 unconjugated
产品编号 ABIN1107997
发货至: 中国
  • 抗原 See all Lactoferrin (LTF) 抗体
    Lactoferrin (LTF) (Lactotransferrin (LTF))
    适用
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    宿主
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    小鼠
    克隆类型
    • 161
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    单克隆
    标记
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    This Lactoferrin antibody is un-conjugated
    应用范围
    • 154
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    Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    Thi antibody reacts with human lactoferrin (LF), an 80 kDa glycoprotein.
    交叉反应 (详细)
    Species reactivity (tested):Human
    纯化方法
    Purified
    克隆位点
    265-1K1
    亚型
    IgG1
    Top Product
    Discover our top product LTF Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2 - 8 °C.
  • 抗原
    Lactoferrin (LTF) (Lactotransferrin (LTF))
    别名
    Lactotransferrin (LTF 产品)
    别名
    LTF antibody, GIG12 antibody, HLF2 antibody, LF antibody, Lf antibody, Csp82 antibody, MMS10R antibody, Ms10r antibody, PLF antibody, TFEW antibody, conalbumin antibody, lactotransferrin antibody, transferrin antibody, transferrin (ovotransferrin) antibody, LTF antibody, CpipJ_CPIJ000114 antibody, TF antibody, Ltf antibody
    背景
    Lactoferrin was first isolated from human milk and plays an important part in the immune system and helps to fight infections. Lactoferrin promotes the health of the gastro-intestinal system by improving the intestinal microbial balance. In addition, LF can be found in epithelia and most body fluids and secretions. Lactoferrin is secreted in plasma by neutrophils. Its plasma concentration also represents a positive relation to the total pool of neutrophils and the rate of neutrophil turnover. In inflammation lactoferrin is released from secondary granules of neutrophilic leukocytes into the extracellular medium. Therefore the extracellular lactoferrin concentration can be used as an index for neutrophil activation. Lactoferrin strongly binds to iron and this iron binding property is considered to be an important antimicrobial. Human lactoferrin binds to bacterial products through its highly positively charged N-terminus, it kills various bacteria, most probably by inducing intracellular changes in these bacteria without affecting the membrane permeability. Cleavage by pepsin of lactoferrin leads to the release of lactoferricin H. This 47 amino acid peptide has more antimicrobial activity than its precursor and it can inhibit the classical but not the alternative complement pathway. Lactoferrin also plays a role in signal transduction, immunomodulation and has antiadhesive, anticancer, antiviral activity.Synonyms: EC=3.4.21, LF, LTF, Lactoferrin, Talalactoferrin
    基因ID
    4057
    NCBI登录号
    NP_001186078
    UniProt
    P02788
    途径
    Transition Metal Ion Homeostasis
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