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HRH3 抗体 (C-Term)

HRH3 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1107535
发货至: 中国
  • 抗原 See all HRH3 抗体
    HRH3 (Histamine Receptor H3 (HRH3))
    抗原表位
    • 15
    • 15
    • 10
    • 8
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 80
    • 49
    • 32
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    人, 大鼠, 小鼠
    宿主
    • 80
    • 3
    • 1
    克隆类型
    • 81
    • 3
    多克隆
    标记
    • 43
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This HRH3 antibody is un-conjugated
    应用范围
    • 70
    • 26
    • 18
    • 18
    • 16
    • 13
    • 6
    • 5
    • 5
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB)
    特异性
    This antibody detects Histamine H3 receptor (C-term). No cross reactivity with other proteins.
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse, rat
    纯化方法
    Immunogen affinity purified
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminal of human HRH3 .Remarks: Sequence is different to the related rat sequence by two amino acides.
    亚型
    IgG
    Top Product
    Discover our top product HRH3 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 溶解方式
    0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    缓冲液
    5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
    储存液
    Sodium azide, Thimerosal (Merthiolate)
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    HRH3 (Histamine Receptor H3 (HRH3))
    别名
    Histamine H3 Receptor (HRH3 产品)
    别名
    GPCR97 antibody, HH3R antibody, AW049250 antibody, H3R antibody, histamine receptor H3 antibody, HRH3 antibody, Hrh3 antibody
    背景
    The histamine receptor H3 (HRH3) is a presynaptic autoreceptor on histamine neurons in the brain and a presynaptic heteroreceptor in nonhistamine-containing neurons in both the central and peripheral nervous systems1. The deduced 445-amino acid HRH3 protein contains 7 predicted transmembrane domains. And it shares 22 % and 21.4 % amino acid sequence homology with the H1 (HRH1) and H2 (HRH2) receptors, respectively. The expression of recombinant HRH3 in a variety of cell lines conferred an ability to inhibit adenylate cyclase in response to histamine, but not to acetylcholine or any other biogenic amine. Additionally, HRH3 was most notably observed throughout the thalamus, the ventromedial hypothalamus, and the caudate nucleus. Strong expression was also seen in layers II, V,and VIb of the cerebral cortex, in the pyramidal layers of the hippocampus, and in olfactory tubercle.Synonyms: G-protein coupled receptor 97, GPCR97, HH3R
    基因ID
    11255
    NCBI登录号
    NP_009163
    UniProt
    Q9Y5N1
    途径
    cAMP Metabolic Process, Feeding Behaviour
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