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HES1 抗体 (C-Term)

This anti-HES1 antibody is a 兔 多克隆 antibody detecting HES1 in WB, IHC (fro) 和 EIA. Suitable for 小鼠.
产品编号 ABIN1107521
发货至: 中国

Quick Overview for HES1 抗体 (C-Term) (ABIN1107521)

抗原

See all HES1 抗体
HES1 (Hes Family bHLH Transcription Factor 1 (HES1))

适用

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小鼠

宿主

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克隆类型

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多克隆

标记

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This HES1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    C-Term

    特异性

    Reacts with Mouse 30 kDa Hes1 protein. Cross reacts with Rat and Human.

    纯化方法

    Affinity Chromatography on Protein A

    免疫原

    Synthetic peptide derived from C-terminal domain of HES-1 protein
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 溶解方式

    Restore in distilled water.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Prior to reconstitution store the antibody at -20 °C. Store reconstituted antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer
  • 抗原

    HES1 (Hes Family bHLH Transcription Factor 1 (HES1))

    别名

    HES1

    背景

    HES1 is a nuclear protein belonging to th basic helix-loop-helix family of transcription factors with a basic helix-loop-helix (bHLH) domain and an Orange domain. The basic domain of HES1 contains a helix interrupting protein that binds to the N-box rather than the canonical E-box. An immediate early response gene to growth factor, HES1 is reported as having a dual function of both transcriptional activator and silencer of acid alpha-glucosidase (GAA), thus contributing to the subtle tissue-specific control of housekeeping genes such as GAA. HES1 a transcriptional repressor of genes which require a bHLH protein for their transcription and also the formation of a complex with a corepressor protein (Groucho) such as TLE2. HES1 may act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1.Synonyms: HES-1, HHL, HL, HRY, Hairy and enhancer of split 1, Hairy homolog, Hairy-like

    基因ID

    15205

    NCBI登录号

    NP_032261

    途径

    DNA Damage Repair
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