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HES1 抗体

This 小鼠 单克隆 anti-HES1 antibody (Clone 7C2g2) specifically detects HES1 in WB 和 EIA. The antibody is reactive with 人 samples.
产品编号 ABIN1107520
发货至: 中国
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Quick Overview for HES1 抗体 (ABIN1107520)

抗原

See all HES1 抗体
HES1 (Hes Family bHLH Transcription Factor 1 (HES1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This HES1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)

克隆位点

7C2g2
  • 特异性

    Reacts with Human 30 kDa HES-1 protein. May cross react with Mouse and Rat.

    纯化方法

    Affinity Chromatography on Protein A

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 溶解方式

    Restore in distilled water.

    缓冲液

    0.1 M Tris, 0.1 M Glycine and 2 % Sucrose, None
  • 抗原

    HES1 (Hes Family bHLH Transcription Factor 1 (HES1))

    别名

    HES1

    背景

    HES1 is a nuclear protein belonging to th basic helix-loop-helix family of transcription factors with a basic helix-loop-helix (bHLH) domain and an Orange domain. The basic domain of HES1 contains a helix interrupting protein that binds to the N-box rather than the canonical E-box. An immediate early response gene to growth factor, HES1 is reported as having a dual function of both transcriptional activator and silencer of acid alpha-glucosidase (GAA), thus contributing to the subtle tissue-specific control of housekeeping genes such as GAA. HES1 a transcriptional repressor of genes which require a bHLH protein for their transcription and also the formation of a complex with a corepressor protein (Groucho) such as TLE2. HES1 may act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1.Synonyms: HES-1, HHL, HL, HRY, Hairy and enhancer of split 1, Hairy homolog, Hairy-like

    基因ID

    3280

    途径

    DNA Damage Repair
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