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EDNRB 抗体 (Middle Region)

EDNRB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1107094
发货至: 中国
  • 抗原 See all EDNRB 抗体
    EDNRB (Endothelin Receptor Type B (EDNRB))
    抗原表位
    • 16
    • 15
    • 11
    • 7
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 244-258, Middle Region
    适用
    • 70
    • 36
    • 36
    • 11
    • 8
    • 8
    • 8
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 82
    • 7
    • 2
    • 1
    克隆类型
    • 81
    • 11
    多克隆
    标记
    • 38
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This EDNRB antibody is un-conjugated
    应用范围
    • 69
    • 25
    • 19
    • 15
    • 13
    • 13
    • 13
    • 12
    • 10
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    特异性
    This antibody detects Endothelin B Receptor. No cross reactivity with other proteins.
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Immunogen Affinity Chromatography
    免疫原
    A synthetic peptide corresponding to a sequence in the middle region of Human EDNR-B (244-258aa).
    亚型
    IgG
    Top Product
    Discover our top product EDNRB Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 溶解方式
    0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    缓冲液
    5 mg BSA, 0.9 mg Nacl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg Sodium Azide
    储存液
    Sodium azide, Thimerosal (Merthiolate)
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    EDNRB (Endothelin Receptor Type B (EDNRB))
    别名
    Endothelin B Receptor (EDNRB 产品)
    别名
    ABCDS antibody, ET-B antibody, ET-BR antibody, ETB antibody, ETBR antibody, ETRB antibody, HSCR antibody, HSCR2 antibody, WS4A antibody, Ednra antibody, Etb antibody, ETR-b antibody, ETb antibody, Sox10m1 antibody, EDNRB antibody, abcds antibody, etb antibody, etrb antibody, hscr antibody, hscr2 antibody, endothelin receptor type B antibody, EDNRB antibody, Ednrb antibody, ednrb antibody
    背景
    Endothelin Receptor B (EDNR-B), also called endothelin receptor, nonselective type (ETB, ETRB). It is a G-protein-coupled receptor with seven transmembrane domains which is required for the development of melanocytes and enteric neurons and migration of melanoblasts and enteric neuroblasts. The EDNRB gene spans 24 kilobases and consists of seven exons and six introns.This gene was expressed in human glaucomatous optic nerves and mapped to 13q22. The cDNA fragment for horse EDNRB contained a 1329 bp open reading frame which encoded 443 amino acid residues. The predicted amino acid sequence was 89, 91 and 85 % identical to human, bovine and mouse as well as rat EDNRB respectively, but only 55 % identical to the human, bovine and rat endothelin A receptor (EDNRA). EDNRB plays an essential role in the normal development of two neural crest-derived cell lineages, epidermal melanocytes and enteric neurons in three mammalian species--humans, mice, and rats. The EDNRB-deficient rat may also prove valuable in defining the postnatal physiologic role of this receptor.Synonyms: ABCDS, EDNRB, ET-B, ET-BR, ETB, ETBR, ETRB, Endothelin receptor non-selective type, HSCR, HSCR2, WS4A, endothelin receptor type B
    基因ID
    1910
    NCBI登录号
    NP_000106
    UniProt
    P24530
    途径
    Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process
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