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CYP2E1 抗体 (C-Term)

CYP2E1 适用: 人, 小鼠, 大鼠 WB, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1106885
发货至: 中国
  • 抗原 See all CYP2E1 抗体
    CYP2E1 (Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1))
    抗原表位
    • 15
    • 11
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 71
    • 50
    • 37
    • 15
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    人, 小鼠, 大鼠
    宿主
    • 78
    • 6
    • 3
    克隆类型
    • 75
    • 12
    多克隆
    标记
    • 44
    • 12
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CYP2E1 antibody is un-conjugated
    应用范围
    • 64
    • 27
    • 19
    • 14
    • 13
    • 9
    • 9
    • 7
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    This antibody detects CYP2E1 (C-term).
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse, rat
    纯化方法
    Immunogen affinity purified
    免疫原
    A synthetic peptide mapping at the C-terminal of human P450ⅡE1 .Remarks: Sequence is different from the related mouse sequence by single amino acid.
    亚型
    IgG
    Top Product
    Discover our top product CYP2E1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 溶解方式
    0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    缓冲液
    5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
    储存液
    Sodium azide, Thimerosal (Merthiolate)
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CYP2E1 (Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1))
    别名
    CYP2E1 (CYP2E1 产品)
    别名
    CYP2E1 antibody, CYP2E antibody, CYPIIE1 antibody, CPE1 antibody, P450-J antibody, P450C2E antibody, Cyp2e antibody, cytochrome P450, family 2, subfamily E, polypeptide 1 antibody, cytochrome P450 2E1 antibody, cytochrome P450 2E1-like antibody, cytochrome P450 family 2 subfamily E member 1 antibody, cytochrome P450, family 2, subfamily e, polypeptide 1 antibody, CYP2E1 antibody, PTRG_07411 antibody, LOC100342572 antibody, LOC100727914 antibody, LOC101843716 antibody, Cyp2e1 antibody
    背景
    P450IIE1, also known as CYP2E1, is a member of the P450IIE subfamily which is ethanol-inducible. It has at least 1 gene which is mapped to 10q24.3-qter, and a second is likely in rat and in man1. Both the rat and human proteins encoded by this gene contain 493 amino acids and calculated molecular masses of 56,634 and 56,916 daltons, respectively2. In addition, genetic polymorphisms in the 5-prime flanking region of the human P450IIE1 gene affected its binding of transacting factor and changed its transcriptional regulation, which may lead to interindividual differences of microsomal drug oxidation activity3. P450IIE1 is an important enzyme for the catalysis of the conversion of ethanol to acetaldehyde and to acetate in humans,and it is also involved in the metabolism of nitrosamines. Due to the possible correlation of P450IIE1 genes with malignancy, clinical studies of RFLP patterns of these genes in cancer may be useful.Synonyms: CYP2E, CYPIIE1, Cytochrome P450 2E1, Cytochrome P450-J
    基因ID
    1571
    NCBI登录号
    NP_000764
    UniProt
    P05181
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