COL18A1 抗体 (Chain alpha 1)
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- 抗原 See all COL18A1 抗体
- COL18A1 (Collagen, Type XVIII, alpha 1 (COL18A1))
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抗原表位
- Chain alpha 1
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This COL18A1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
- 特异性
- Monoclonal antibody 1837-46 reacts with endostatin, a 20 kDa C-terminal fragment of collagen XVIII.
- 交叉反应 （详细）
- Species reactivity (tested):Human
- 纯化方法
- Protein G
- 克隆位点
- 1837-46
- 亚型
- IgG2b
- Top Product
- Discover our top product COL18A1 Primary Antibody
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anti-Collagen, Type XVIII, alpha 1 (COL18A1) (AA 1581-1680) antibody
COL18A1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Collagen, Type XVIII, alpha 1 (COL18A1) (AA 1154-1335) antibodyCOL18A1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Collagen, Type XVIII, alpha 1 (COL18A1) antibodyCOL18A1 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Collagen, Type XVIII, alpha 1 (COL18A1) (AA 1600-1754) antibodyCOL18A1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Collagen, Type XVIII, alpha 1 (COL18A1) antibodyCOL18A1 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Collagen, Type XVIII, alpha 1 (COL18A1) (C-Term) antibodyCOL18A1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Collagen, Type XVIII, alpha 1 (COL18A1) antibodyCOL18A1 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Collagen, Type XVIII, alpha 1 (COL18A1) (AA 1311-1339) antibodyCOL18A1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB22701 unconjugated
anti-Collagen, Type XVIII, alpha 1 (COL18A1) (AA 237-263), (N-Term) antibodyCOL18A1 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB22312 unconjugated
anti-Collagen, Type XVIII, alpha 1 (COL18A1) (C-Term) antibodyCOL18A1 适用: 人, 大鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.1 mg/mL
- 缓冲液
- PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- COL18A1 (Collagen, Type XVIII, alpha 1 (COL18A1))
- Abstract
- COL18A1 产品
- 别名
- KNO antibody, KNO1 antibody, KS antibody, cb371 antibody, cb529 antibody, fc96d06 antibody, sb:cb529 antibody, wu:fb47h10 antibody, wu:fb77g12 antibody, wu:fc50f04 antibody, wu:fc96d06 antibody, wu:fk02h12 antibody, kno antibody, kno1 antibody, collagen type XVIII alpha 1 chain antibody, collagen type XVIII alpha 1 chain a antibody, collagen, type XVIII, alpha 1 antibody, collagen type XVIII alpha 1 antibody, COL18A1 antibody, col18a1a antibody, Col18a1 antibody, col18a1 antibody
- 背景
- Endostatin is able to evoke non-uniform response for proliferation, cell mount and migration of entothelial cells, with different endostatin binding characteristic, leads to the assumption that endostatin effect is strongly dependent from endothelial cell type. Furthermore endostatin inhibits angiogenesis and tumor growth in vivo by inducing apoptosis in endothelial cells. The local delivery of endostatin seems to specifically affect tumor-associated microvessels by reduction of the vessel density, diameter and functionality. Tumor cell migration and invasion was greatly reduced in the endostatin treated animals. Endostatin is non-toxic and does not induce acquired drug resistance and has therefore become a potent new therapy strategy in solid neoplasias. This therapy appear to have high potential not only for the treatment of gliomas, the most common brain tumours, but also of other tumours. The ability of endostatin to inhibit neoangiogenesis is mediated, at least in part, by Zn2+ binding and elastase processing. Widespread endostatin expression was found in elastic fibers in vessel walls and in some other basement membrane zones. Endostatin is released by neurons to accumulate in amyloid plaques in Alzheimer's disease.Synonyms: COL18A1, Endostatin, KNO1
- 基因ID
- 80781
- NCBI登录号
- NP_085059
- UniProt
- P39060
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