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FAS 抗体

FAS 适用: 人 WB, FACS, Neut 宿主: 小鼠 Monoclonal ZB4 unconjugated
产品编号 ABIN1106613
发货至: 中国
  • 抗原 See all FAS 抗体
    FAS (TNF Receptor Superfamily, Member 6 (FAS))
    适用
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    宿主
    • 157
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    小鼠
    克隆类型
    • 155
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    单克隆
    标记
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    This FAS antibody is un-conjugated
    应用范围
    • 156
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    Western Blotting (WB), Flow Cytometry (FACS), Neutralization (Neut)
    特异性
    This antibody reacts with Fas.
    无交叉反应
    小鼠
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Protein A agarose
    免疫原
    Recombinant human Fas
    克隆位点
    ZB4
    亚型
    IgG1
    Top Product
    Discover our top product FAS Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 50 % glycerol, pH 7.2
    储存液
    Azide free
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store (in aliquots) at -20 °C.
  • 抗原
    FAS (TNF Receptor Superfamily, Member 6 (FAS))
    别名
    CD95 / FAS (FAS 产品)
    背景
    It is now widely accepted that apoptosis plays an important role in the selection of immature thymocytes and Ag-primed peripheral T cells. Fas (also known as CD95/APO-1) is a cell surface protein belonging to the tumor necrosis factor receptor superfamily, which is expressed in a variety of normal and neoplastic cells. Binding of FasL to Fas or crosslinking of Fas by anti-Fas monoclonal antibodies results in rapid induction of apoptosis in Fas expressing cells. Clone ZB4 is known as Fas blocking, Fas neutralizing or Fas antagonistic antibody, whereas anti-human Fas antibody (clone CH-11) is known as the agonistic antibody.Synonyms: APT1, Apo-1 antigen, FAS1, FASLG receptor, TNFRSF6, Tumor necrosis factor receptor superfamily member 6
    基因ID
    355
    NCBI登录号
    NP_000034
    UniProt
    P25445
    途径
    p53 Pathway, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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