FAS 抗体
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北京 101111
Quick Overview for FAS 抗体 (ABIN1106610)
抗原
See all FAS 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody recognizes the human Fas antigen specifically.
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无交叉反应
- 小鼠
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Ammonium sulfate precipitation and affinity chromatography on protein A agarose
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免疫原
- Recombinant human Fas
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亚型
- IgG1
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anti-TNF Receptor Superfamily, Member 6 (FAS) antibody
FAS 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 150-250) antibodyFAS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor Superfamily, Member 6 (FAS) antibodyFAS 适用: 人 WB, FACS, ELISA, ICC 宿主: 小鼠 Monoclonal 4F8H6 unconjugated
anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 87-109), (N-Term) antibodyFAS 适用: 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 22-172) antibodyFAS 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 22-169) antibodyFAS 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 21-170) antibodyFAS 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 1-335) antibodyFAS 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1B6 unconjugated
anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 20-119) antibodyFAS 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 5B4 unconjugated
anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 20-119) antibodyFAS 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 2G3 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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溶解方式
- Prepare a stock solution by dissolving the lyophilized antibody in 100 μL of distilled water.
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缓冲液
- PBS ( pH 7.2), 0.09 % NaN3, 1 % sucrose
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Prior to reconstitution store at 2-8 °C. Following reconstitution store (in aliquots) at -20 °C.
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: "Induction and regulation of Fas-mediated apoptosis in human thyroid epithelial cells." in: Molecular endocrinology (Baltimore, Md.), Vol. 19, Issue 3, pp. 804-11, (2005) (PubMed).
: "Functional proteomic screen identifies a modulating role for CD44 in death receptor-mediated apoptosis." in: Cancer research, Vol. 65, Issue 5, pp. 1887-96, (2005) (PubMed).
: "Homocysteine enhances endothelial apoptosis via upregulation of Fas-mediated pathways." in: Hypertension, Vol. 43, Issue 6, pp. 1208-13, (2004) (PubMed).
: "Suppression of Akt signaling induces Fas ligand expression: involvement of caspase and Jun kinase activation in Akt-mediated Fas ligand regulation." in: Molecular and cellular biology, Vol. 22, Issue 2, pp. 680-91, (2001) (PubMed).
: "Fas drives cell cycle progression in glioma cells via extracellular signal-regulated kinase activation." in: Cancer research, Vol. 60, Issue 6, pp. 1766-72, (2000) (PubMed).
: "Vascular endothelial cells and smooth muscle cells differ in expression of Fas and Fas ligand and in sensitivity to Fas ligand-induced cell death: implications for vascular disease and therapy." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 20, Issue 2, pp. 309-16, (2000) (PubMed).
: "Functional Fas ligand expression in thyrocytes from patients with Graves' disease." in: The Journal of clinical endocrinology and metabolism, Vol. 84, Issue 8, pp. 2896-902, (1999) (PubMed).
: "The involvement of Fas-Fas ligand pathway in fibrosing lung diseases." in: American journal of respiratory cell and molecular biology, Vol. 20, Issue 1, pp. 53-60, (1999) (PubMed).
: "Fas ligand is present in human erythroid colony-forming cells and interacts with Fas induced by interferon gamma to produce erythroid cell apoptosis." in: Blood, Vol. 91, Issue 4, pp. 1235-42, (1998) (PubMed).
: "Perforin, Fas/Fas ligand, and TNF-alpha pathways as specific and bystander killing mechanisms of hepatitis C virus-specific human CTL." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 158, Issue 11, pp. 5283-91, (1997) (PubMed).
: "Stimulated human lamina propria T cells manifest enhanced Fas-mediated apoptosis." in: The Journal of clinical investigation, Vol. 98, Issue 11, pp. 2616-22, (1997) (PubMed).
: "Expression of Fas/Apo-1 (CD95) and apoptosis in tumor cells from patients with plasma cell disorders." in: Blood, Vol. 86, Issue 5, pp. 1939-45, (1995) (PubMed).
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: "Induction and regulation of Fas-mediated apoptosis in human thyroid epithelial cells." in: Molecular endocrinology (Baltimore, Md.), Vol. 19, Issue 3, pp. 804-11, (2005) (PubMed).
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- FAS (TNF Receptor Superfamily, Member 6 (FAS))
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别名
- CD95 / FAS
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背景
- It is now widely accepted that apoptosis plays an important role in the selection of immature thymocytes and Ag-primed peripheral T cells. Fas antigen is a cell-surface protein that mediates apoptosis. It is expressed in various tissues including the thymus and has structural homology with a number of cell-surface receptors, including tumor necrosis factor receptor and nerve growth factor receptor.Synonyms: APT1, Apo-1 antigen, FAS1, FASLG receptor, TNFRSF6, Tumor necrosis factor receptor superfamily member 6
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基因ID
- 355
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NCBI登录号
- NP_000034
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UniProt
- P25445
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途径
- p53 Pathway, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
抗原
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