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CD68 抗体

CD68 适用: 大鼠 FACS, WB, IHC (p), IP, IHC (fro) 宿主: 小鼠 Monoclonal ED1 unconjugated
产品编号 ABIN1106532
发货至: 中国
  • 抗原 See all CD68 抗体
    CD68 (CD68 Molecule (CD68))
    适用
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    大鼠
    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD68 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    This Monoclonal Antibody ED1 is useful for detecting Rat monocytes and macrophages and isolated dendritic (veiled) cells in the blood. The antibody recognises a single chain glycoprotein of 90-100 kDa. Weak cell surface expression also occurs. The antigen is expressed by the majority of tissue macrophages and weakly by peripheral blood granulocytes. Studies have shown that the antigen recognised by ED1 has many characteristics in common with Mouse macrosialin and Human CD68. Antigen, Epitope: CD68, ED1 recognises a 92 kDa cytoplasmic protein. The epitope has not been further characterized. Antigen Distribution: The antigen is found on 90 % of monocytes in the peripheral blood. It is also expressed by 98 % of isolated dendritic (veiled) cells.
    交叉反应 (详细)
    Species reactivity (tested):Rat: Monocytes Macrophages, Dendritic Cells.
    纯化方法
    Affinity Chromatography
    克隆位点
    ED1
    亚型
    IgG1
    Top Product
    Discover our top product CD68 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, pH 7.2, 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • 抗原
    CD68 (CD68 Molecule (CD68))
    别名
    CD68 (CD68 产品)
    别名
    Lamp4 antibody, Scard1 antibody, gp110 antibody, GP110 antibody, LAMP4 antibody, SCARD1 antibody, CD68 molecule antibody, CD68 antigen antibody, Cd68 molecule antibody, CD68 antibody, Cd68 antibody
    背景
    The CD68 antigen is a 37kD transmembrane protein that is post-translationally glycosylated to give a protein of 87-115kD. CD68 is specifically expressed by tissue macrophages, Langerhans cells and at low levels by dendritic cells. It could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. It binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin bearing substrates or other cells.Synonyms: Gp110, Macrophage marker, Macrosialin
    基因ID
    287435
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