CBLL1 抗体
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- 抗原 See all CBLL1 抗体
- CBLL1 (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence-Like 1 (CBLL1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CBLL1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
- This antibody reacts with human Hakai, a c-Cbl-like protein.
- 交叉反应 （详细）
- Species reactivity (tested):Human
- 纯化方法
- Protein A
- 亚型
- IgG
- Top Product
- Discover our top product CBLL1 Primary Antibody
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anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence-Like 1 (CBLL1) (AA 1-100) antibody
CBLL1 适用: 人 WB, IF, ELISA 宿主: 小鼠 Monoclonal 3B12 unconjugated
anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence-Like 1 (CBLL1) (C-Term) antibodyCBLL1 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 斑马鱼, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence-Like 1 (CBLL1) (AA 413-462) antibodyCBLL1 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence-Like 1 (CBLL1) (N-Term) antibodyCBLL1 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence-Like 1 (CBLL1) (C-Term) antibodyCBLL1 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.1 mg/mL
- 缓冲液
- PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store at 2 - 8 °C.
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- 抗原
- CBLL1 (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence-Like 1 (CBLL1))
- 别名
- CBLL1 / RNF188 (CBLL1 产品)
- 别名
- HAKAI antibody, RNF188 antibody, zgc:55308 antibody, CBLL1 antibody, AI467391 antibody, Hakai antibody, c-Cbl-like antibody, cbll1 antibody, hakai antibody, rnf188 antibody, Cbl proto-oncogene like 1 antibody, Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase S homeolog antibody, Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase antibody, Casitas B-lineage lymphoma-like 1 antibody, Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase L homeolog antibody, CBLL1 antibody, cbll1.S antibody, Cbll1 antibody, cbll1 antibody, cbll1.L antibody
- 背景
- Hakai is an E-cadherin binding protein, which has been identified as an E3 ubiquitin-ligase. Hakai contains SH2, RING, zinc-finger and proline-rich domains. Hakai interacts with E-cadherin in a tyrosine phosphorylation-dependent manner, inducing ubiquitination of the E-cadherin complex. Expression of Hakai in epithelial cells disrupts cell-cell contacts and enhances endocytosis of E-cadherin and cell motility. By promoting the endocytosis and dynamic recycling or destruction of E-cadherin complexes, Hakai is able to control epithelial-mesenchymal transitions under physiological and pathological conditions.Synonyms: Casitas B-lineage lymphoma-transforming sequence-like protein 1, E3 ubiquitin-protein ligase Hakai, HAKAI, RING finger protein 188, c-Cbl-like protein 1
- 基因ID
- 79872
- NCBI登录号
- NP_079090
- UniProt
- Q75N03
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