AKAP12 抗体 (C-Term)
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- 抗原 See all AKAP12 抗体
- AKAP12 (A Kinase (PRKA) Anchor Protein 12 (AKAP12))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This AKAP12 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- This anrtibody is expected to recognize both reported isoforms of AKAP12.
- 交叉反应 （详细）
- Species reactivity (tested):Human.
- 纯化方法
- Affinity Chromatography
- 免疫原
- Peptide with sequence C-KQERESAKSELTES, from the C-Terminus of the protein sequence according to NP_005091.2, NP_653080.1. Genename: AKAP12
- Top Product
- Discover our top product AKAP12 Primary Antibody
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anti-A Kinase (PRKA) Anchor Protein 12 (AKAP12) (AA 1485-1782) antibody
AKAP12 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 12 (AKAP12) (AA 701-900) antibodyAKAP12 适用: 大鼠, 小鼠 WB, ELISA, IHC (p), IHC (fro), FACS, IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 12 (AKAP12) (AA 1675-1782) antibodyAKAP12 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C5 unconjugated
anti-A Kinase (PRKA) Anchor Protein 12 (AKAP12) (C-Term) antibodyAKAP12 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 12 (AKAP12) antibodyAKAP12 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 12 (AKAP12) antibodyAKAP12 适用: Cow WB, IHC, IP 宿主: 绵羊 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 12 (AKAP12) antibodyAKAP12 适用: 大鼠 WB 宿主: 绵羊 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 12 (AKAP12) (C-Term) antibodyAKAP12 适用: 人 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 12 (AKAP12) (C-Term) antibodyVerified AKAP12 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 12 (AKAP12) antibodyAKAP12 适用: 大鼠, Cow WB, IHC, IP 宿主: 绵羊 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- AKAP12 (A Kinase (PRKA) Anchor Protein 12 (AKAP12))
- 别名
- AKAP12 (AKAP12 产品)
- 别名
- akap12 antibody, cb27 antibody, esr1 antibody, fb72g12 antibody, id:ibd1202 antibody, sb:cb27 antibody, si:ch73-192g21.1 antibody, wu:fb72g12 antibody, wu:fc21c03 antibody, AKAP12 antibody, AI317366 antibody, SSeCKS antibody, Srcs5 antibody, Tsga12 antibody, AKAP12A antibody, AKAP12B antibody, AKAP12G antibody, AKAP250 antibody, A kinase (PRKA) anchor protein 12b antibody, A-kinase anchoring protein 12 antibody, A kinase (PRKA) anchor protein (gravin) 12 antibody, akap12b antibody, AKAP12 antibody, Akap12 antibody
- 背景
- Gravin (also known as A Kinase Anchor Protein 12, AKAP12) was cloned from a cDNA expression library screened with serum, from a myasthenia gravis patient. Antibodies to Gravin were found in 22 out of 72 myasthemia gravis patients and absent in sera of normal individuals. This protein is a myristoylated high molecular weight cytoplasmic protein expressed in endothelial cells, cultured fibroblasts and osteosarcoma cells and highly expressed in the brain. Gravin can bind kinases like PKA and PKC by different domains of the protein and can localize these kinases to specific domains in the cell. Upon differentiation of NT2 cells to neurons (NT2 N), Gravin expression is up regulated and enriched at the inner peripheral cortex in close proximity to the plasma membrane. In differentiated cells, gravin is co-localized with PKCbII, PKCa and PKA. Decreased binding of PKCa to gravin was found after activation of PKC.Synonyms: A-kinase anchor protein 12, A-kinase anchor protein 250 kDa, AKAP250, Gravin, Myasthenia gravis autoantigen, PRKA12
- 分子量
- 191 kDa (NP_005091.2) and 181 kDa (NP_653080.1).
- 基因ID
- 9590
- NCBI登录号
- NP_005091
- 途径
- cAMP Metabolic Process
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