Acetyl-CoA Carboxylase beta 抗体 (Internal Region)
-
- 抗原 See all Acetyl-CoA Carboxylase beta (ACACB) 抗体
- Acetyl-CoA Carboxylase beta (ACACB)
-
抗原表位
- Internal Region
-
适用
- 人
-
宿主
- 山羊
-
克隆类型
- 多克隆
-
标记
- This Acetyl-CoA Carboxylase beta antibody is un-conjugated
-
应用范围
- Enzyme Immunoassay (EIA)
- 序列
- C-QLGEPDLSDK DRKD
- 特异性
- This antibody recognizes ACACB
- 交叉反应 (详细)
- Species reactivity (tested):Human.
- 纯化方法
- Affinity Chromatography
- 免疫原
- Synthetic Peptide (C-QLGEPDLSDKDRKD) from the internal region of Human ACACB (NP_001084.2). Genename: ACACB
- Top Product
- Discover our top product ACACB Primary Antibody
-
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 浓度
- 0.5 mg/mL
- 缓冲液
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
- 抗原
- Acetyl-CoA Carboxylase beta (ACACB)
- 别名
- Acetyl-CoA Carboxylase 2 (ACACB 产品)
- 别名
- F15C21.2 antibody, F15C21_2 antibody, acetyl-CoA carboxylase 2 antibody, ACC2 antibody, ACCB antibody, HACC275 antibody, Acc2 antibody, AI597064 antibody, AW743042 antibody, Accb antibody, acetyl-CoA carboxylase 2 antibody, acetyl-CoA carboxylase beta antibody, acetyl-Coenzyme A carboxylase beta antibody, ACC2 antibody, ACACB antibody, Acacb antibody
- 背景
- Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. Exercise diminishes the activity of acetyl-CoA carboxylase in human muscle. ACC alpha (ACC1) is the rate-limiting enzyme in the biogenesis of long-chain fatty acids, and ACC beta (ACC2) is thought to control mitochondrial fatty acid oxidation. These two isoforms of ACC control the amount of fatty acids in the cells. ACC beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. The gene encoding ACC beta maps to human chromosome 12 and encodes a mitochondiral protein expressed in heart and skeletal muscle. The catalytic core of ACC beta is homologous to that of ACC alpha, except for an additional peptide of about 150 amino acids at the N-terminusSynonyms: ACACB, ACC2, ACCB
- 基因ID
- 32
- NCBI登录号
- NP_001084
- 途径
- AMPK Signaling, Ribonucleoside Biosynthetic Process
-