FOXA1 抗体
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- 抗原 See all FOXA1 抗体
- FOXA1 (Forkhead Box A1 (FOXA1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FOXA1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- Multiple isoforms of FOXA1 exists as a result of alternative splicing event.
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- Rabbit polyclonal FOXA1 antibody was raised against a 17 amino acid peptide near the center of human FOXA1.
- 亚型
- IgG
- Top Product
- Discover our top product FOXA1 Primary Antibody
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- 应用备注
- FOXA1 antibody can be used for detection of FOXA1 by Western blot at 1 - 2 μg/mL.
- 说明
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(IN) Forkhead box protein A1
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS containing 0.02 % Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- 储存条件
- 4 °C/-20 °C
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- 抗原
- FOXA1 (Forkhead Box A1 (FOXA1))
- 别名
- FOXA1 (FOXA1 产品)
- 别名
- HNF3A antibody, TCF3A antibody, Hnf-3a antibody, Hnf3a antibody, Tcf-3a antibody, Tcf3a antibody, fkd7 antibody, forkhead-7 antibody, HNF3-alpha antibody, HNF3alpha antibody, fkh2 antibody, foxa1 antibody, hnf3a antibody, tFoxA1 antibody, tcf3a antibody, xfkh2 antibody, fkh antibody, FOXA1 antibody, Ci-fkh antibody, HNF-3a antibody, forkhead box A1 antibody, forkhead box A1 S homeolog antibody, forkhead homolog antibody, forkhead box A1 L homeolog antibody, FOXA1 antibody, Foxa1 antibody, foxa1 antibody, foxa1.S antibody, fkh antibody, foxa1.L antibody
- 背景
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FOXA1 is one of three members of the FOXA family, a subset of the forkhead family of transcription factors which play vital roles in development. It has also been implicated in the development of a number of other organs including the androgen and estrogen regulated tissues of the breast and prostate. FOXA1 modulates the transcriptional activity of nuclear hormone receptors and regulates apoptosis by inhibiting the expression of BCL-2. It is an essential protein for the transcriptional activity of both androgen receptor (AR) and estrogen receptor-alpha (ER). FOXA1 plays a pivotal role from early stage cancer through to drug resistant and metastatic disease. FOXA1 is not only an attractive therapeutic target but could potentially function as a novel biomarker.
Synonyms: Forkhead box protein A1, hepatocyte nuclear factor 3-alpha, HNF3A, HNF-3A, HNF-3-alpha, Transcription factor 3A, TCF3A, TCF-3A - 分子量
- 52 kDa
- 基因ID
- 3169
- NCBI登录号
- NP_004487
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis
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