WIPI2 抗体 (N-Term)
-
- 抗原 See all WIPI2 抗体
- WIPI2 (WD Repeat Domain, Phosphoinositide Interacting 2 (WIPI2))
-
抗原表位
- N-Term
-
适用
- 人, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This WIPI2 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA
- 特异性
- WIPI2 antibody is human and rat reactive. Multiple isoforms of WIPI2 are known to exist. WIPI2 antibody is predicted to not cross-react with WIPI1.
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- Rabbit polyclonal WIPI2 antibody was raised against a 17 amino acid peptide near the amino terminus of human WIPI2.
- 亚型
- IgG
- Top Product
- Discover our top product WIPI2 Primary Antibody
-
-
- 应用备注
- WIPI2 antibody can be used for detection of WIPI2 by Western blot at 1 - 2 μg/mL.
- 说明
-
(NT) WD repeat domain phosphoinositide interacting 2
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS containing 0.02 % Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- WIPI2 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
- 有效期
- 12 months
-
- 抗原
- WIPI2 (WD Repeat Domain, Phosphoinositide Interacting 2 (WIPI2))
- 别名
- WIPI2 (WIPI2 产品)
- 别名
- ATG18B antibody, Atg21 antibody, WIPI-2 antibody, 1110018O08Rik antibody, 2510001I10Rik antibody, WD repeat domain, phosphoinositide interacting 2 L homeolog antibody, WD repeat domain, phosphoinositide interacting 2 antibody, wipi2.L antibody, WIPI2 antibody, Wipi2 antibody
- 背景
-
WD repeat proteins play a role in many essential biologic functions, regulating the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. WIPI2, also known as ATG18B or ATG21, is a human homolog to yeast ATG18 and contains three WD repeats and has a 7-bladed propeller structure with a conserved motif that facilitates its interaction with other proteins. It is recruited to early autophagosomal structures along with Atg16L and ULK1 and is required for the formation of LC3-positive autophagosomes. Along with the highly related WIPI1, WIPI2 is found at the plasma membrane in addition to autophagosomal membranes.
Synonyms: WD repeat domain phosphoinositide interacting 2, WIPI-2, WD40 repeat protein interacting with phosphoinositides 2, WIPI49-like protein 2, ATG18B, ATG21, CGI-50 - 分子量
- 50 kDa
- 基因ID
- 26100
- NCBI登录号
- NP_056425
-