Pellino 1 抗体 (C-Term)
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- 抗原 See all Pellino 1 (PELI1) 抗体
- Pellino 1 (PELI1) (Pellino E3 Ubiquitin Protein Ligase 1 (PELI1))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Pellino 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- Rabbit polyclonal Pellino 1 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human Pellino 1.
- 亚型
- IgG
- Top Product
- Discover our top product PELI1 Primary Antibody
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anti-Pellino E3 Ubiquitin Protein Ligase 1 (PELI1) (AA 1-250) antibody
PELI1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pellino E3 Ubiquitin Protein Ligase 1 (PELI1) (C-Term) antibodyPELI1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Pellino E3 Ubiquitin Protein Ligase 1 (PELI1) (AA 107-156) antibodyPELI1 适用: 人, 小鼠, 大鼠, Cow, 马, 斑马鱼, 犬, 兔, 豚鼠, Hamster, 非洲爪蟾, Bat, 猴, 小鸡, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Pellino E3 Ubiquitin Protein Ligase 1 (PELI1) (AA 17-242) antibodyPELI1 适用: 人, Cow WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Pellino 1 antibody can be used for detection of Pellino 1 by Western blot at 1 - 2 μg/mL.
- 说明
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(CT) Pellino E3 ubiquitin protein ligase 1
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS containing 0.02 % Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- 储存条件
- 4 °C
- 储存方法
- Pellino 1 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
- 有效期
- 12 months
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- 抗原
- Pellino 1 (PELI1) (Pellino E3 Ubiquitin Protein Ligase 1 (PELI1))
- 别名
- PELI1 (PELI1 产品)
- 别名
- 2810468L03Rik antibody, A930031K15Rik antibody, AA409794 antibody, AI586297 antibody, D11Ertd676e antibody, peli1 antibody, peli1.L antibody, pellino1 antibody, xpellino1 antibody, wu:fd12d01 antibody, zgc:153297 antibody, pellino E3 ubiquitin protein ligase 1 antibody, pellino 1 antibody, pellino E3 ubiquitin protein ligase 1 S homeolog antibody, pellino E3 ubiquitin protein ligase 1b antibody, PELI1 antibody, Peli1 antibody, peli1.S antibody, peli1b antibody
- 背景
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The Pellino proteins are a highly homologous family of E3 ubiquitin ligases that act as upstream mediators in Toll-like receptor (TLR) pathways that lead to activation of MAP kinases and transcription factors. Pellino 1 is required for interleukin-1-mediated signaling through its interaction with the IRAK4-IRAK-TRAF6 complex, ultimately resulting in the activation of NF-kB. Like other members of the Pellino family, Pellino 1 is an E3 ubiquitin ligase, able to catalyze the polyubiquitination of IRAK1. It is activated via phosphorylation by either IRAK1 and IRAK4 or the IKK-related kinases IKK-epsilon and TBK1. In addition to phosphorylation, Pellino 1 activity is also modulated via ubiquitination and sumoylation.
Synonyms: Pellino E3 ubiquitin protein ligase 1, PELI1, pellino1, pellino-1 - 分子量
- 46 kDa
- 基因ID
- 57162
- NCBI登录号
- NP_065702
- 途径
- Activation of Innate immune Response, Toll-Like Receptors Cascades
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