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beta-2 Microglobulin 抗体

B2M 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 2D3E5 unconjugated
产品编号 ABIN1045266
发货至: 中国
  • 抗原 See all beta-2 Microglobulin (B2M) 抗体
    beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
    适用
    • 202
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This beta-2 Microglobulin antibody is un-conjugated
    应用范围
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    ELISA, Immunohistochemistry (IHC)
    特异性
    Specific for B2M denatured and native forms
    交叉反应
    纯化方法
    Protein G purified
    纯度
    > 95 %
    免疫原
    Recombinant human Beta-2-microglobulin protein
    克隆位点
    2D3E5
    亚型
    IgG1, IgG1 kappa
    Top Product
    Discover our top product B2M Primary Antibody
  • 应用备注
    Recommended dilution:IHC:1:50-1:500,
    说明

    Other species are not tested. Please decide the specificity by homology

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Avoid freeze and thaw cycles.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Stefanović, Djukanović, Cukuranović, Bukvić, Ležaić, Marić, Ogrizovic, Jovanović, Vlahovic, Pešić, Djordjević: "Beta2-microglobulin and alpha1-microglobulin as markers of Balkan endemic nephropathy, a worldwide disease." in: Renal failure, Vol. 33, Issue 2, pp. 176-83, (2011) (PubMed).

    Sharifiaghdas, Kashi, Eshratkhah: "Evaluating percutaneous nephrolithotomy-induced kidney damage by measuring urinary concentrations of β2-microglobulin." in: Urology journal, Vol. 8, Issue 4, pp. 277-82, (2011) (PubMed).

    Johnston, Cassidy, OConnell, ORiordan, Gallagher, Maguire, Wynne, Cagney, Ryan, Conlon, McMorrow: "Identification of β2-microglobulin as a urinary biomarker for chronic allograft nephropathy using proteomic methods." in: Proteomics. Clinical applications, Vol. 5, Issue 7-8, pp. 422-31, (2011) (PubMed).

    Kals, Zagura, Serg, Kampus, Zilmer, Unt, Lieberg, Eha, Peetsalu, Zilmer: "β2-microglobulin, a novel biomarker of peripheral arterial disease, independently predicts aortic stiffness in these patients." in: Scandinavian journal of clinical and laboratory investigation, Vol. 71, Issue 4, pp. 257-63, (2011) (PubMed).

    Dieterle, Perentes, Cordier, Roth, Verdes, Grenet, Pantano, Moulin, Wahl, Mahl, End, Staedtler, Legay, Carl, Laurie, Chibout, Vonderscher, Maurer: "Urinary clusterin, cystatin C, beta2-microglobulin and total protein as markers to detect drug-induced kidney injury." in: Nature biotechnology, Vol. 28, Issue 5, pp. 463-9, (2010) (PubMed).

  • 抗原
    beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
    别名
    B2M (B2M 产品)
    别名
    Ly-m11 antibody, beta2-m antibody, beta2m antibody, bwm antibody, wu:fa94c05 antibody, wu:fb10a09 antibody, b2m-W01 antibody, b2m-W03 antibody, b2m-Z01 antibody, b2m-Z02 antibody, b2m-Z03 antibody, B2M antibody, b2m antibody, B2MG antibody, wu:fb66f11 antibody, wu:fj01f08 antibody, zgc:64161 antibody, b-2-m antibody, beta-2-microglobulin antibody, beta-2 microglobulin antibody, beta-2-microglobulin S homeolog antibody, beta-2-microglobulin, like antibody, B2M antibody, B2m antibody, b2m antibody, b2m.S antibody, b2ml antibody
    背景

    Background: Beta 2 Microglobulin non-covalently associates with the 44 kDa alpha chain to form the HLA Class I antigen complex. Human beta 2 Microglobulin associated with HLA Class I antigens are expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes.

    Aliases: B2M, CDABP0092, HDCMA22P

    UniProt
    P61769
    途径
    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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