AMPK alpha 抗体
(SNF1A/AMP-Activated Protein Kinase (SNF1A))
The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| AMPK alpha 抗体 (AA 353-367) | 人 | 兔 Polyclonal |
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| AMPK alpha 抗体 (C-Term) | 大鼠 | 兔 Polyclonal |
|
|
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| AMPK alpha 抗体 (C-Term) | 人 | 兔 Polyclonal |
|
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Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 353-367
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- C-Term
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- C-Term
Latest Publications for our AMPK alpha 抗体
: "Exercise-induced α-ketoglutaric acid stimulates muscle hypertrophy and fat loss through OXGR1-dependent adrenal activation." in: The EMBO journal, Vol. 39, Issue 7, pp. e103304, (2020) (PubMed).
: "miR-29a regulated ER-positive breast cancer cell growth and invasion and is involved in the insulin signaling pathway." in: Oncotarget, Vol. 8, Issue 20, pp. 32566-32575, (2018) (PubMed).
: "Anti-osteoporosis activity of Sanguinarine in preosteoblast MC3T3-E1 cells and an ovariectomized rat model." in: Journal of cellular physiology, Vol. 233, Issue 6, pp. 4626-4633, (2018) (PubMed).
: "Diallyl Disulfide Inhibits Breast Cancer Stem Cell Progression and Glucose Metabolism by Targeting CD44/PKM2/AMPK Signaling." in: Current cancer drug targets, Vol. 18, Issue 6, pp. 592-599, (2018) (PubMed).
: "Respiratory Syncytial Virus Replication Is Promoted by Autophagy-Mediated Inhibition of Apoptosis." in: Journal of virology, Vol. 92, Issue 8, (2018) (PubMed).
: "Regulation of AMPK-related glycolipid metabolism imbalances redox homeostasis and inhibits anchorage independent growth in human breast cancer cells." in: Redox biology, Vol. 17, pp. 180-191, (2018) (PubMed).
: "High expressions of LDHA and AMPK as prognostic biomarkers for breast cancer." in: Breast (Edinburgh, Scotland), Vol. 30, pp. 39-46, (2017) (PubMed).
: "Myostatin inhibits eEF2K-eEF2 by regulating AMPK to suppress protein synthesis." in: Biochemical and biophysical research communications, Vol. 494, Issue 1-2, pp. 278-284, (2017) (PubMed).
: "Anhydroicaritin improves diet-induced obesity and hyperlipidemia and alleviates insulin resistance by suppressing SREBPs activation." in: Biochemical pharmacology, Vol. 122, pp. 42-61, (2017) (PubMed).
: "Enhancement of Glucose Metabolism via PGC-1α Participates in the Cardioprotection of Chronic Intermittent Hypobaric Hypoxia." in: Frontiers in physiology, Vol. 7, pp. 219, (2016) (PubMed).
: "miR-29a regulated ER-positive breast cancer cell growth and invasion and is involved in the insulin signaling pathway." in: Oncotarget, Vol. 8, Issue 20, pp. 32566-32575, (2018) (PubMed).
: "Anti-osteoporosis activity of Sanguinarine in preosteoblast MC3T3-E1 cells and an ovariectomized rat model." in: Journal of cellular physiology, Vol. 233, Issue 6, pp. 4626-4633, (2018) (PubMed).
: "Diallyl Disulfide Inhibits Breast Cancer Stem Cell Progression and Glucose Metabolism by Targeting CD44/PKM2/AMPK Signaling." in: Current cancer drug targets, Vol. 18, Issue 6, pp. 592-599, (2018) (PubMed).
: "Respiratory Syncytial Virus Replication Is Promoted by Autophagy-Mediated Inhibition of Apoptosis." in: Journal of virology, Vol. 92, Issue 8, (2018) (PubMed).
: "Regulation of AMPK-related glycolipid metabolism imbalances redox homeostasis and inhibits anchorage independent growth in human breast cancer cells." in: Redox biology, Vol. 17, pp. 180-191, (2018) (PubMed).
: "High expressions of LDHA and AMPK as prognostic biomarkers for breast cancer." in: Breast (Edinburgh, Scotland), Vol. 30, pp. 39-46, (2017) (PubMed).
: "Myostatin inhibits eEF2K-eEF2 by regulating AMPK to suppress protein synthesis." in: Biochemical and biophysical research communications, Vol. 494, Issue 1-2, pp. 278-284, (2017) (PubMed).
: "Anhydroicaritin improves diet-induced obesity and hyperlipidemia and alleviates insulin resistance by suppressing SREBPs activation." in: Biochemical pharmacology, Vol. 122, pp. 42-61, (2017) (PubMed).
: "Enhancement of Glucose Metabolism via PGC-1α Participates in the Cardioprotection of Chronic Intermittent Hypobaric Hypoxia." in: Frontiers in physiology, Vol. 7, pp. 219, (2016) (PubMed).
Aliases for AMPK alpha 抗体
protein kinase AMP-activated catalytic subunit alpha 2 (PRKAA2) 抗体AMPK 抗体
AMPK2 抗体
AMPKa2 抗体
PRKAA 抗体
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