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AMPK alpha 产品

(SNF1A/AMP-Activated Protein Kinase (SNF1A))
The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq, Jul 2008].

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Featured AMPK alpha Categories

AMPK alpha 抗体

High quality antibodies with extensive validation data.

AMPK alpha ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Recommended AMPK alpha 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IF, ICC
Validations
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  • (4)
Cat. No. ABIN6255610
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, IF
Validations
  • (4)
Cat. No. ABIN7138633
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (2)
Cat. No. ABIN7138787
Quantity 100 μL
Datasheet Datasheet

Recommended AMPK alpha ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6971288
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6971290
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6971289
Quantity 96 tests
Datasheet Datasheet

Latest Publications for our AMPK alpha Products

Yuan, Xu, Jiang, Cai, Wang, Peng, Sun, Zhu, Zhang, Yue, He, Yang, Zeng, Du, Zhang, Ibrahimi, Schaul, Jiang, Wang, Sun, Wang, Liu, Wang, Wang, Zhu, Gao, Xi, Yin, Li, Xu, Zhang, Shu: "Exercise-induced α-ketoglutaric acid stimulates muscle hypertrophy and fat loss through OXGR1-dependent adrenal activation." in: The EMBO journal, Vol. 39, Issue 7, pp. e103304, (2020) (PubMed).

Li, Xiong, Xu, Duan, Yang, Zhou, Tu: "miR-29a regulated ER-positive breast cancer cell growth and invasion and is involved in the insulin signaling pathway." in: Oncotarget, Vol. 8, Issue 20, pp. 32566-32575, (2018) (PubMed).

Zhang, Xie, Wang, Zhang, Yang: "Anti-osteoporosis activity of Sanguinarine in preosteoblast MC3T3-E1 cells and an ovariectomized rat model." in: Journal of cellular physiology, Vol. 233, Issue 6, pp. 4626-4633, (2018) (PubMed).

Xie, Huang, Tang, Ye, Yang, Guo, Tian, Xie, Peng, Xie: "Diallyl Disulfide Inhibits Breast Cancer Stem Cell Progression and Glucose Metabolism by Targeting CD44/PKM2/AMPK Signaling." in: Current cancer drug targets, Vol. 18, Issue 6, pp. 592-599, (2018) (PubMed).

Li, Li, Zeng, Yang, Liu, Zhang, Song, Yao, Ma, Li, Wang, Wei: "Respiratory Syncytial Virus Replication Is Promoted by Autophagy-Mediated Inhibition of Apoptosis." in: Journal of virology, Vol. 92, Issue 8, (2018) (PubMed).

Arab Sadeghabadi, Nourbakhsh, Pasalar, Emamgholipour, Golestani, Larijani, Razzaghy-Azar: "Reduced gene expression of sirtuins and active AMPK levels in children and adolescents with obesity and insulin resistance." in: Obesity research & clinical practice, Vol. 12, Issue 2, pp. 167-173, (2018) (PubMed).

Yang, He, Yao, Tan, Zhu, Li, Guo, Wei: "Regulation of AMPK-related glycolipid metabolism imbalances redox homeostasis and inhibits anchorage independent growth in human breast cancer cells." in: Redox biology, Vol. 17, pp. 180-191, (2018) (PubMed).

Koroglu, Tola, Temel Yuksel, Aslan Cetin, Turhan, Topcu, Dag: "Maternal serum AMP-activated protein kinase levels in mild and severe preeclampsia." in: The journal of maternal-fetal & neonatal medicine, pp. 1-6, (2018) (PubMed).

Huang, Li, Xie, Ye, Chen, Song, Tang, Xie: "High expressions of LDHA and AMPK as prognostic biomarkers for breast cancer." in: Breast (Edinburgh, Scotland), Vol. 30, pp. 39-46, (2017) (PubMed).

Deng, Luo, Lai, Song, Peng, Wei: "Myostatin inhibits eEF2K-eEF2 by regulating AMPK to suppress protein synthesis." in: Biochemical and biophysical research communications, Vol. 494, Issue 1-2, pp. 278-284, (2017) (PubMed).

Synonyms and alternative names related to AMPK alpha

protein kinase AMP-activated catalytic subunit alpha 2 (PRKAA2), AMPK, AMPK2, AMPKa2, PRKAA

Protein level used designations for AMPK alpha

  • 5'-AMP-activated protein kinase catalytic subunit alpha-2
  • 5'-AMP-activated protein kinase, catalytic alpha-2 chain
  • ACACA kinase
  • AMPK subunit alpha-2
  • AMPK-alpha-2 chain
  • HMGCR kinase
  • acetyl-CoA carboxylase kinase
  • hydroxymethylglutaryl-CoA reductase kinase
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