The protein encoded by this gene is a type I transmembrane protein. It is thought to modulate bone morphogenetic protein (BMP) receptor function by serving as an accessory or coreceptor, and thus facilitates or hinders BMP binding. It is known that the mouse AMN gene is expressed in the extraembryonic visceral endoderm layer during gastrulation, but it is found to be mutated in amnionless mouse. The encoded protein has sequence similarity to short gastrulation (Sog) and procollagen IIA proteins in Drosophila. [provided by RefSeq, Jul 2008].
Pannérec, Migliavacca, De Castro, Michaud, Karaz, Goulet, Rezzi, Ng, Bosco, Larbi, Feige: "Vitamin B12 deficiency and impaired expression of amnionless during aging." in: Journal of cachexia, sarcopenia and muscle, Vol. 9, Issue 1, pp. 41-52, (2019) (PubMed).
Galamb, Sipos, Spisák, Galamb, Krenács, Valcz, Tulassay, Molnár et al.: "Potential biomarkers of colorectal adenoma-dysplasia-carcinoma progression: mRNA expression profiling and in situ protein detection on TMAs reveal 15 sequentially upregulated and 2 downregulated ..." in: Cellular oncology : the official journal of the International Society for Cellular Oncology, Vol. 31, Issue 1, pp. 19-29, (2008) (PubMed).
Aliases for AMN 抗体
amnion associated transmembrane protein L homeolog (amn.L) 抗体 amnion associated transmembrane protein (AMN) 抗体 amnionless (Amn) 抗体 5033428N14Rik 抗体 amnionless 抗体 AV002116 抗体 MGC81896 抗体 PRO1028 抗体