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AKR1C1 抗体

(Dihydrodiol Dehydrogenase (DDH))
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq, Jul 2008].

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  • 抗原: AKR1C1 (DDH)
  • Primary
Catalog no. 产品 适用 宿主 / 克隆类型 应用 价格和交货时间
ABIN5514650
AKR1C1 抗体 (C-Term) DDH · Primary Antibody 人 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • 100 μL
  • 25 μL
发货至: 中国
Primary Antibody
  • WB (Western Blotting: 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
unconjugated
抗原表位
C-Term
产品编号 ABIN5514650
100 μL (More quantities available)
发货至: 中国
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Latest Publications for our AKR1C1 抗体

Zhu, Hu, Zeng, Chang, Ge, Wang, Yan, Zhao, Cao, Ying, Gu, Zheng, He, Yang: "The SIRT2-mediated deacetylation of AKR1C1 is required for suppressing its pro-metastasis function in Non-Small Cell Lung Cancer." in: Theranostics, Vol. 10, Issue 5, pp. 2188-2200, (2020) (PubMed).

Zeng, Zhu, You, Dong, Yang, Zhu, He: "Liquiritin, as a Natural Inhibitor of AKR1C1, Could Interfere With the Progesterone Metabolism." in: Frontiers in physiology, Vol. 10, pp. 833, (2019) (PubMed).

Zhu, Chang, Yan, Hu, Zeng, Zhou, Yuan, Ying, Cao, He, Yang: "AKR1C1 Activates STAT3 to Promote the Metastasis of Non-Small Cell Lung Cancer." in: Theranostics, Vol. 8, Issue 3, pp. 676-692, (2018) (PubMed).

Chen, Solomides, Parekh, Simpkins, Simpkins: "Cisplatin resistance in human cervical, ovarian and lung cancer cells." in: Cancer chemotherapy and pharmacology, Vol. 75, Issue 6, pp. 1217-27, (2015) (PubMed).

Han, Bourboulia, Jensen-Taubman, Isaac, Wei, Stetler-Stevenson: "An endogenous inhibitor of angiogenesis inversely correlates with side population phenotype and function in human lung cancer cells." in: Oncogene, Vol. 33, Issue 9, pp. 1198-206, (2014) (PubMed).

Choi, Ryoo, Kang, Kwak: "The sensitivity of cancer cells to pheophorbide a-based photodynamic therapy is enhanced by Nrf2 silencing." in: PLoS ONE, Vol. 9, Issue 9, pp. e107158, (2014) (PubMed).

Ebert, Kisiela, Wsól, Maser: "Proteasome inhibitors MG-132 and bortezomib induce AKR1C1, AKR1C3, AKR1B1, and AKR1B10 in human colon cancer cell lines SW-480 and HT-29." in: Chemico-biological interactions, Vol. 191, Issue 1-3, pp. 239-49, (2011) (PubMed).

Buytaert, Matroule, Durinck, Close, Kocanova, Vandenheede, de Witte, Piette, Agostinis: "Molecular effectors and modulators of hypericin-mediated cell death in bladder cancer cells." in: Oncogene, Vol. 27, Issue 13, pp. 1916-29, (2008) (PubMed).

McLoughlin, Irving, Brownlees, Brion, Leroy, Miller: "Mint2/X11-like colocalizes with the Alzheimer's disease amyloid precursor protein and is associated with neuritic plaques in Alzheimer's disease." in: The European journal of neuroscience, Vol. 11, Issue 6, pp. 1988-94, (1999) (PubMed).

Borg, Straight, Kaech, de Taddéo-Borg, Kroon, Karnak, Turner, Kim, Margolis: "Identification of an evolutionarily conserved heterotrimeric protein complex involved in protein targeting." in: The Journal of biological chemistry, Vol. 273, Issue 48, pp. 31633-6, (1998) (PubMed).

Aliases for AKR1C1 抗体

aldo-keto reductase family 1 member C1 (AKR1C1) 抗体
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) (AKR1C1) 抗体
2-ALPHA-HSD 抗体
20-ALPHA-HSD 抗体
C9 抗体
DD1 抗体
DD1/DD2 抗体
DDH 抗体
DDH1 抗体
H-37 抗体
HAKRC 抗体
HBAB 抗体
MBAB 抗体
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