AKR1C1 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for AKR1C1 抗体 (C-Term) (ABIN5514650)
抗原
See all AKR1C1 (DDH) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
原理
- AKR1C1 Antibody - C-terminal region
-
序列
- LVAYSALGSH REEPWVDPNS PVLLEDPVLC ALAKKHKRTP ALIALRYQLQ
-
产品特性
- This is a rabbit polyclonal antibody against AK1C1. It was validated on Western Blot.
-
纯化方法
- Affinity purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human AK1C1
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP76080-100UG
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.5 mg/mL
-
缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- prevent freeze-thaw cycles
-
储存条件
- 4 °C,-20 °C
-
储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
-
- AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))
-
别名
- AKR1C1
-
背景
-
Background Information: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Gene Name: aldo-keto reductase family 1 member C1
Alternative Symbols: C9, DD1, DDH, DDH1, H-37, HBAB, MBAB, HAKRC, DD1/DD2, 2-ALPHA-HSD, 20-ALPHA-HSD
Protein Name: aldo-keto reductase family 1 member C1
-
分子量
- 35kDa
-
基因ID
- 1645
-
NCBI登录号
- NP_001344
-
UniProt
- Q04828
-
途径
- Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process
抗原
-