AKR1C1 抗体
(Dihydrodiol Dehydrogenase (DDH))
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| AKR1C1 抗体 (N-Term) | 人 | 兔 Polyclonal |
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| AKR1C1 抗体 (AA 1-323) | 人 | 小鼠 Monoclonal |
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| AKR1C1 抗体 (AA 2-218) | 人 | 兔 Polyclonal |
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| AKR1C1 抗体 (N-Term) | 人, 小鼠, 大鼠, 豚鼠, Cow, 犬, 马, 兔, 绵羊 | 兔 Polyclonal |
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| AKR1C1 抗体 (N-Term) | 人, 大鼠, Cow, 犬, 马, 兔, Pig | 兔 Polyclonal |
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| AKR1C1 抗体 (AA 22-248) | 人 | 兔 Polyclonal |
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| AKR1C1 抗体 (AA 22-218) | 人 | 兔 Polyclonal |
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| AKR1C1 抗体 (AA 219-323) (FITC) | 人 | 兔 Polyclonal |
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| AKR1C1 抗体 (Alexa Fluor 680) | 人, 大鼠 | 兔 Polyclonal |
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| AKR1C1 抗体 (Alexa Fluor 555) | 人, 大鼠 | 兔 Polyclonal |
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| AKR1C1 抗体 (Alexa Fluor 647) | 人, 大鼠 | 兔 Polyclonal |
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| AKR1C1 抗体 (Alexa Fluor 750) | 人, 大鼠 | 兔 Polyclonal |
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| AKR1C1 抗体 (Biotin) | 人, 大鼠 | 兔 Polyclonal |
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| AKR1C1 抗体 (Alexa Fluor 488) | 人, 大鼠 | 兔 Polyclonal |
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| AKR1C1 抗体 (Alexa Fluor 594) | 人, 大鼠 | 兔 Polyclonal |
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| AKR1C1 抗体 (AA 22-248) | 人, 小鼠 | 兔 Polyclonal |
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| AKR1C1 抗体 (AA 30-110) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| AKR1C1 抗体 | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| AKR1C1 抗体 (full length) | 人, 小鼠, 大鼠, 豚鼠, Hamster | 小鼠 Monoclonal |
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| AKR1C1 抗体 (full length) | 人, 小鼠, 大鼠, 豚鼠, Hamster | 小鼠 Monoclonal |
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Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- N-Term
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- AT6D10
- 标记
- unconjugated
- 抗体亚型
- IgG1 kappa
- 抗原表位
- AA 1-323
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 2-218
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠, 豚鼠, Cow, 犬, 马, 兔, 绵羊
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- N-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人, 大鼠, Cow, 犬, 马, 兔, Pig
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- N-Term
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IF/ICC (Immunofluorescence (fixed cells): 所列应用)
- IHC (fp) (Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 22-248
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 22-218
Primary Antibody
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- FITC
- 抗体亚型
- IgG
- 抗原表位
- AA 219-323
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 22-248
Primary Antibody
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 30-110
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 质量等级
- Carrier-free
- 适用
- 人, 小鼠, 大鼠, 豚鼠, Hamster
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- AKR1C1-9318
- 标记
- unconjugated
- 抗体亚型
- IgG2b, kappa
- 抗原表位
- full length
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人, 小鼠, 大鼠, 豚鼠, Hamster
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- AKR1C1-9318
- 标记
- unconjugated
- 抗体亚型
- IgG2b, kappa
- 抗原表位
- full length
Latest Publications for our AKR1C1 抗体
: "The SIRT2-mediated deacetylation of AKR1C1 is required for suppressing its pro-metastasis function in Non-Small Cell Lung Cancer." in: Theranostics, Vol. 10, Issue 5, pp. 2188-2200, (2020) (PubMed).
: "Liquiritin, as a Natural Inhibitor of AKR1C1, Could Interfere With the Progesterone Metabolism." in: Frontiers in physiology, Vol. 10, pp. 833, (2019) (PubMed).
: "AKR1C1 Activates STAT3 to Promote the Metastasis of Non-Small Cell Lung Cancer." in: Theranostics, Vol. 8, Issue 3, pp. 676-692, (2018) (PubMed).
: "Cisplatin resistance in human cervical, ovarian and lung cancer cells." in: Cancer chemotherapy and pharmacology, Vol. 75, Issue 6, pp. 1217-27, (2015) (PubMed).
: "An endogenous inhibitor of angiogenesis inversely correlates with side population phenotype and function in human lung cancer cells." in: Oncogene, Vol. 33, Issue 9, pp. 1198-206, (2014) (PubMed).
: "The sensitivity of cancer cells to pheophorbide a-based photodynamic therapy is enhanced by Nrf2 silencing." in: PLoS ONE, Vol. 9, Issue 9, pp. e107158, (2014) (PubMed).
: "Proteasome inhibitors MG-132 and bortezomib induce AKR1C1, AKR1C3, AKR1B1, and AKR1B10 in human colon cancer cell lines SW-480 and HT-29." in: Chemico-biological interactions, Vol. 191, Issue 1-3, pp. 239-49, (2011) (PubMed).
: "Molecular effectors and modulators of hypericin-mediated cell death in bladder cancer cells." in: Oncogene, Vol. 27, Issue 13, pp. 1916-29, (2008) (PubMed).
: "Mint2/X11-like colocalizes with the Alzheimer's disease amyloid precursor protein and is associated with neuritic plaques in Alzheimer's disease." in: The European journal of neuroscience, Vol. 11, Issue 6, pp. 1988-94, (1999) (PubMed).
: "Identification of an evolutionarily conserved heterotrimeric protein complex involved in protein targeting." in: The Journal of biological chemistry, Vol. 273, Issue 48, pp. 31633-6, (1998) (PubMed).
: "Liquiritin, as a Natural Inhibitor of AKR1C1, Could Interfere With the Progesterone Metabolism." in: Frontiers in physiology, Vol. 10, pp. 833, (2019) (PubMed).
: "AKR1C1 Activates STAT3 to Promote the Metastasis of Non-Small Cell Lung Cancer." in: Theranostics, Vol. 8, Issue 3, pp. 676-692, (2018) (PubMed).
: "Cisplatin resistance in human cervical, ovarian and lung cancer cells." in: Cancer chemotherapy and pharmacology, Vol. 75, Issue 6, pp. 1217-27, (2015) (PubMed).
: "An endogenous inhibitor of angiogenesis inversely correlates with side population phenotype and function in human lung cancer cells." in: Oncogene, Vol. 33, Issue 9, pp. 1198-206, (2014) (PubMed).
: "The sensitivity of cancer cells to pheophorbide a-based photodynamic therapy is enhanced by Nrf2 silencing." in: PLoS ONE, Vol. 9, Issue 9, pp. e107158, (2014) (PubMed).
: "Proteasome inhibitors MG-132 and bortezomib induce AKR1C1, AKR1C3, AKR1B1, and AKR1B10 in human colon cancer cell lines SW-480 and HT-29." in: Chemico-biological interactions, Vol. 191, Issue 1-3, pp. 239-49, (2011) (PubMed).
: "Molecular effectors and modulators of hypericin-mediated cell death in bladder cancer cells." in: Oncogene, Vol. 27, Issue 13, pp. 1916-29, (2008) (PubMed).
: "Mint2/X11-like colocalizes with the Alzheimer's disease amyloid precursor protein and is associated with neuritic plaques in Alzheimer's disease." in: The European journal of neuroscience, Vol. 11, Issue 6, pp. 1988-94, (1999) (PubMed).
: "Identification of an evolutionarily conserved heterotrimeric protein complex involved in protein targeting." in: The Journal of biological chemistry, Vol. 273, Issue 48, pp. 31633-6, (1998) (PubMed).
Aliases for AKR1C1 抗体
aldo-keto reductase family 1 member C1 (AKR1C1) 抗体aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) (AKR1C1) 抗体
2-ALPHA-HSD 抗体
20-ALPHA-HSD 抗体
C9 抗体
DD1 抗体
DD1/DD2 抗体
DDH 抗体
DDH1 抗体
H-37 抗体
HAKRC 抗体
HBAB 抗体
MBAB 抗体
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