Waglerin 1
-
- 抗原
- Waglerin 1
- 应用范围
- Blocking Reagent (BR)
- 原理
- Waglerin is a nAChR blocker
- 序列
- Gly-Gly-Lys-Pro-Asp-Leu-Arg-Pro-Cys9-His-Pro-Pro-Cys13-His-Tyr-Ile-Pro-Arg-Pro-Lys-Pro-Arg-OH(Disulfide bonds between Cys9-Cys13)
-
- 限制
- 仅限研究用
-
-
- 抗原
- Waglerin 1
- 背景
- Waglerin 1 (Wtx-1) is a peptide originally isolated from the venom of the Wagler's pit viper (Trimeresurus wagleri). This 22 amino-acid peptide is a competitive antagonist of muscle nicotinic acetylcholine receptors. Waglerin 1 binds selectively to epsilon subunit of nAChR. Some studies have demonstrated that Waglerin 1 has an effect on ionotropic GABA receptors. It may potentiate or depress I(GABA) depending on the neurons. Some derivatives of Waglerin 1 are currently used in cosmetics to reduce wrinkles.
- 分子量
- 2520 Da
-
You are here:
