omega-conotoxin MVIIC (omega contoxin MVIIC)
-
- 抗原
- Conotoxin MVIIC omega
- 应用范围
- Blocking Reagent (BR)
- 原理
- omega-conotoxin MVIIC is a calcium channel blocker
- 序列
- Cys1-Lys-Gly-Lys-Gly-Ala-Pro-Cys8-Arg-Lys-Thr-Met-Tyr-Asp-Cys15-Cys16-Ser-Gly-Ser-Cys20-Gly-Arg-Arg-Gly-Lys-Cys26-NH2Disulfide bonds between Cys1-Cys16, Cys8-Cys20and Cys15-Cys26
-
- 限制
- 仅限研究用
-
-
- 抗原
- Conotoxin MVIIC omega
- 背景
- Omega-conotoxin MVIIC has been isolated from the venom of the cone Conus magus. omega-conotoxin MVIIC inhibits presynaptic Ca2+ channels, including the Ca2+ channels responsible for Ca2+ uptake by rat brain synaptosomes, the P-type Ca2+ channels in cerebellar Purkinje cells, and a significant fraction of omega-conotoxin GVIA-resistant currents in hippocampal CA1 neurons. omega-conotoxin MVIIC also presents an inhibition of omega-conotoxin GVIA-resistant depolarization-induced neurotransmitter release in cerebellar neurons of rats.
- 分子量
- 2750.2 Da
- CAS-编号
- 147794-23-8
-
You are here:
