Vitamin K-dependent protein C (PROC) ELISA试剂盒

PROC encodes a vitamin K-dependent plasma glycoprotein. 再加上,我们可以发PROC 抗体 (216)PROC 蛋白 (37)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
PROC 25268 P31394
PROC 19123 P33587
PROC 5624 P04070
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产品编号 适用 灵敏度 范围 图像 规格 供应商 交付 价格 详细
小鼠 6.9 pg/mL 15.6 pg/mL - 1000 pg/mL 96 Tests Log in to see 13至16个工作日
$682.11
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0.78 ng/mL 3.12-200 ng/mL Typical standard curve 96 Tests Log in to see 13至16个工作日
$1,026.67
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大鼠 0.58 ng/mL 1.56 ng/mL - 100 ng/mL 96 Tests Log in to see 13至16个工作日
$720.00
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0.1 ng/mL 1.0-25 ng/mL   96 Tests Log in to see 15至18个工作日
$707.14
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豚鼠 0.1 ng/mL 1.0-25 ng/mL   96 Tests Log in to see 15至18个工作日
$707.14
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Pig 3.75 ng/mL 6.25-400 ng/mL   96 Tests Log in to see 12至14个工作日
$715.00
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小鸡 9.375 ng/mL 15.625-1000 ng/mL   96 Tests Log in to see 12至14个工作日
$715.00
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0.188 ng/mL 0.313-20 ng/mL   96 Tests Log in to see 12至14个工作日
$715.00
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0.1 ng/mL 1.0-25 ng/mL   96 Tests Log in to see 15至18个工作日
$707.14
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绵羊
  96 Tests Log in to see 15至18个工作日
$707.14
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引用最多的PROC ELISA试剂盒

  1. Mouse (Murine) PROC ELISA Kit for Sandwich ELISA - ABIN415711 : Kawasaki, Okamoto, Kawasaki, Sata: Thrombomodulin improved liver injury, coagulopathy, and mortality in an experimental heatstroke model in mice. in Anesthesia and analgesia 2014 (PubMed)

  2. Human PROC ELISA Kit for Competition ELISA - ABIN612753 : Foster, Yoshitake, Davie: The nucleotide sequence of the gene for human protein C. in Proceedings of the National Academy of Sciences of the United States of America 1985 (PubMed)
    Show all 8 Pubmed References

适于 PROC 相互作用对的更多 ELISA 试剂盒

Mouse (Murine) Vitamin K-dependent protein C (PROC) interaction partners

  1. Data show that activated protein C signals via protease activated receptors PAR2 (显示 F2RL1 ELISA试剂盒)/PAR3 (显示 F2RL2 ELISA试剂盒) to expand Treg cells, mitigating the disease in mice.

  2. insulin (显示 INS ELISA试剂盒) and aPC (显示 APC ELISA试剂盒) converge on a common spliced-X-box binding protein-1 (显示 XBP1 ELISA试剂盒) (sXBP1) signaling pathway to maintain endoplasmic reticulum (ER) homeostasis.

  3. loss of the convertase furin (显示 FURIN ELISA试剂盒) or PC5 (显示 PCSK5 ELISA试剂盒)/6 in hepatocytes results in a approximately 30% decrease in APC (显示 APC ELISA试剂盒) levels, with no significant contribution from PACE4. We conclude that prior convertase cleavage of protein C in hepatocytes is critical for its thrombin (显示 F2 ELISA试剂盒) activation.

  4. APC (显示 APC ELISA试剂盒) modifies pulmonary fibrosis by limiting thrombin (显示 F2 ELISA试剂盒)-dependent macrophage recruitment.

  5. Small interfering RNA-mediated silencing of protein C in apolipoprotein E (显示 APOE ELISA试剂盒)-deficient mice creates a condition that allows the occurrence of spontaneous atherothrombosis.

  6. These findings reveal a novel biological function and mechanism of the protein C pathway in which protein S and the aPC (显示 APC ELISA试剂盒)-cleaved form of fV are cofactors for anti-inflammatory cell signaling by aPC (显示 APC ELISA试剂盒) in the context of endotoxemia and infection

  7. activated PC-EPCR-PAR1 signaling promotes hematopoietic stem cell retention in bone marrow.

  8. impaired EPCR (显示 PROCR ELISA试剂盒)/protein C-binding interactions not only result in procoagulant and proinflammatory effects, but also impact hematopoiesis

  9. SOD prevents thrombomodulin (显示 THBD ELISA试剂盒) methionine oxidation, promotes protein C activation, and protects against arterial and venous thrombosis in mice.

  10. sPLA2 (显示 PLA2G2A ELISA试剂盒)-V plays a thrombogenic role by impairing the ability of EPCR (显示 PROCR ELISA试剂盒) to promote protein C activation.

Human Vitamin K-dependent protein C (PROC) interaction partners

  1. Laboratory tests and direct sequencing of PROC and SERPINC1 (显示 SERPINC1 ELISA试剂盒) were conducted for the patient and his family members. Coagulation tests revealed that the patient presented type I antithrombin (显示 SERPINC1 ELISA试剂盒) deficiency combined with decreased protein C activity resulting from a small insertion mutation c.848_849insGATGT in SERPINC1 (显示 SERPINC1 ELISA试剂盒) and a short deletion variant c.572_574delAGA in PROC.

  2. Using protein C-factor VII (显示 TH ELISA试剂盒) chimera demonstrate that APC (显示 APC ELISA试剂盒) light chain amino acid residues outside the EPCR (显示 PROCR ELISA试剂盒)-binding site enable cytoprotective PAR1 signaling.

  3. We recently identified a venous thrombosis patient whose plasma level of protein C antigen is normal, but its anticoagulant activity is only 34 % of the normal level. Genetic analysis revealed that the proband and her younger brother carry a novel heterozygous mutation c.346G>A, p.Gly74Ser (G74S) in PROC.

  4. Developed functional protein S assays that measure both the activated protein C- and TFPI (显示 TFPI ELISA试剂盒)-cofactor activities of protein S in plasma, which are hardly if at all affected by the FV Leiden mutation.

  5. Protein C seems inversely associated with mortality in patients with advanced prostate, lung and pancreatic cancer. Further research should validate protein C as a biomarker for mortality, and explore the effects of protein C on progression of cancer.

  6. Genetically higher protein C was associated with a lower risk of ischaemic heart disease.

  7. EPCR (显示 PROCR ELISA试剂盒) occupancy recruits G-protein coupled receptor kinase 5 (显示 GRK5 ELISA试剂盒), thereby inducing beta-arrestin-2 (显示 ARRB2 ELISA试剂盒) biased PAR1 signaling by both APC (显示 APC ELISA试剂盒) and thrombin (显示 F2 ELISA试剂盒). In

  8. A novel mutation of A309V in PROC was determined in a family of two patients with late onset protein C deficiency

  9. loss of the convertase furin (显示 FURIN ELISA试剂盒) or PC5 (显示 PCSK5 ELISA试剂盒)/6 in hepatocytes results in a approximately 30% decrease in APC (显示 APC ELISA试剂盒) levels, with no significant contribution from PACE4. We conclude that prior convertase cleavage of protein C in hepatocytes is critical for its thrombin (显示 F2 ELISA试剂盒) activation.

  10. Both probands had hereditary protein C deficiencies, for which their parents were all carriers.

Cow (Bovine) Vitamin K-dependent protein C (PROC) interaction partners

  1. Activated protein c is a ghrelin (显示 GHRL ELISA试剂盒) endopeptidase.

  2. Activated protein C(APC (显示 APC ELISA试剂盒)) combined with protein S(PS) had significant antithrombotic effect. APC (显示 APC ELISA试剂盒) combined with PS prolonged clotting time. Dependence on APC (显示 APC ELISA试剂盒)-cofactor activity of PS for expression of anticoagulant activity by APC (显示 APC ELISA试剂盒).

PROC 抗原简介

Antigen Summary

This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.

Gene names and symbols associated with PROC

  • protein C (inactivator of coagulation factors Va and VIIIa), a (proca) 抗体
  • protein C, inactivator of coagulation factors Va and VIIIa (PROC) 抗体
  • protein C (inactivator of coagulation factors Va and VIIIa) (PROC) 抗体
  • protein C, inactivator of coagulation factors Va and VIIIa S homeolog (proc.S) 抗体
  • protein C, inactivator of coagulation factors Va and VIIIa (proc) 抗体
  • vitamin K-dependent protein C (CpipJ_CPIJ000393) 抗体
  • vitamin K-dependent protein C (CpipJ_CPIJ002754) 抗体
  • vitamin K-dependent protein C (CpipJ_CPIJ003717) 抗体
  • vitamin K-dependent protein C (CpipJ_CPIJ003718) 抗体
  • vitamin K-dependent protein C (CpipJ_CPIJ014440) 抗体
  • vitamin K-dependent protein C (CpipJ_CPIJ018032) 抗体
  • vitamin K-dependent protein C (CpipJ_CPIJ018737) 抗体
  • protein C, inactivator of coagulation factors Va and VIIIa (Proc) 抗体
  • protein C (Proc) 抗体
  • APC 抗体
  • MGC64425 抗体
  • PC 抗体
  • PROC 抗体
  • PROC1 抗体
  • si:ch1073-188c16.3 抗体
  • THPH3 抗体
  • THPH4 抗体
  • zgc:63987 抗体

Protein level used designations for PROC

protein C , procl , anticoagulant protein C , vitamin K-dependent protein C , protein C (inactivator of coagulation factors Va and VIIIa) , vitamin K-dependent protein C-like , autoprothrombin IIA , blood coagulation factor XIV , inactivator of coagulation factors Va, VIII , catalytic region , protein C (precursor of vitamin K-dependent serine protease)

GENE ID SPECIES
393327 Danio rerio
395085 Gallus gallus
459593 Pan troglodytes
100302329 Ovis aries
380116 Xenopus laevis
548476 Xenopus (Silurana) tropicalis
100231143 Taeniopygia guttata
100448857 Pongo abelii
6031231 Culex quinquefasciatus
6033948 Culex quinquefasciatus
6035053 Culex quinquefasciatus
6035054 Culex quinquefasciatus
6047546 Culex quinquefasciatus
6052150 Culex quinquefasciatus
6052641 Culex quinquefasciatus
25268 Rattus norvegicus
19123 Mus musculus
5624 Homo sapiens
281428 Bos taurus
101096161 Felis catus
476104 Canis lupus familiaris
100051306 Equus caballus
396954 Sus scrofa
100009223 Oryctolagus cuniculus
699077 Macaca mulatta
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