Succinate Dehydrogenase Complex, Subunit C, Integral Membrane Protein, 15kDa (SDHC) ELISA试剂盒

SDHC encodes one of four nuclear-encoded subunits that comprise succinate dehydrogenase, also known as mitochondrial complex II, a key enzyme complex of the tricarboxylic acid cycle and aerobic respiratory chains of mitochondria. 再加上,我们可以发SDHC 抗体 (49)SDHC 蛋白 (6)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
SDHC 66052 Q9CZB0
大鼠 SDHC SDHC 289217  
SDHC 6391 Q99643
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小鼠 0.071 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Log in to see 13至16个工作日
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引用最多的SDHC ELISA试剂盒

  1. Mouse (Murine) SDHC ELISA Kit for Sandwich ELISA - ABIN1874402 : Yan, Zhang, Jiao, Wang, He, Zhang, Zhang, Lv, Peng, Cai, Tian: Quantitative proteomics in A30P*A53T α-synuclein transgenic mice reveals upregulation of Sel1l. in PLoS ONE 2018 (PubMed)

适于 SDHC 相互作用对的更多 ELISA 试剂盒

Mouse (Murine) Succinate Dehydrogenase Complex, Subunit C, Integral Membrane Protein, 15kDa (SDHC) interaction partners

  1. Studies indicate that the Tet-mev-1 conditional transgenic system can induce mutated SDHC gene in complex II.

  2. complex II plays an essential role in hypoxic reactive oxygen species production.

  3. a sensor for apoptosis induction

Human Succinate Dehydrogenase Complex, Subunit C, Integral Membrane Protein, 15kDa (SDHC) interaction partners

  1. Targeted analysis of DNA methylation array revealed the mesenchymal stem cells in infants born to obese mothers had hypermethylation in genes regulating Fatty Acid Oxidation (PRKAG2, ACC2, CPT1A, SDHC) and corresponding lower mRNA content of these genes. Moreover, mesenchymal stem cells methylation was positively correlated with infant adiposity.

  2. SDHC Promoter hypermethylation is associated with Parasympathetic Paragangliomas.

  3. SDH-deficient gastrointestinal stromal tumors (GISTs) account for approximately 8% of gastric GISTs and are associated with a high rate of distant metastasis, regardless of conventional risk category.

  4. 31% of the paragangliomas in the French Canadian can be explained by the SDHC mutation (c.397C>T, p.[Arg133Ter]).

  5. For classification, tumors were characterized by SDHA, B, C, or D (SDHX) mutations and other genetic and epigenetic alterations, including presence of mutations in germline

  6. Heterozygous germline deletions of up to 104 kb in size were identified in SDHB, SDHC, SDHD and flanking genes in 20 paraganglioma-pheochromocytoma patients. The exact breakpoint could be determined in 16 paraganglioma-pheochromocytoma patients of which 15 were novel deletions

  7. According to international guidelines, SDHB, SDHC, and SDHD genetic testing were performed in this patient, but not SDHA, which would have been prescribed only after surgery, in case of SDHA negative immunohistochemistry

  8. Loss of the SDHC gene is associated with metastatic sympathetic paraganglioma.

  9. This report provides evidence that SDHC promoter methylation can cause Paragangliomas due to SDHC inactivation

  10. significant association with overall survival were confirmed for SDHC gene, SDHD gene and FH gene ... SDHC gene and FH gene were the primary factors contributing to the different overall survival time of colorectal carcinoma

  11. This study strengthens the etiological association of SDH genes with pituitary neoplasia, renal tumorigenesis, and gastric gastrointestinal stromal tumors. Also, pancreatic neuroendocrine tumor falls within the SDH-related tumor spectrum.

  12. Both germline and somatic SDHx mutations/variants occur in sporadic differentiated thyroid cancer (DTC) but are very rare in sporadic breast cancer, and overall loss of SDHx gene expression is a signature of DTC

  13. The discovery of SDHC epimutation provides a unifying explanation for the pathogenesis of SDH-deficient gastrointestinal stromal tumors.

  14. Variant in rs3935401 in the 3' untranslated region of SDHC is associated with hepatocellular carcinoma.

  15. these data suggest epigenetic inactivation of the SDHC gene locus with functional impairment of the SDHC as a plausible alternate mechanism of tumorigenesis in Carney Triad

  16. Overall, 9 of the 34 patients with KIT/PDGFRA wild-type GIST carried mutations in one of the four subunits of the SDH complex (six patients in SDHA, two in SDHB, one in SDHC

  17. Thoracic paragangliomas are common in patients with SDHC mutations, and imaging of this area should be included in surveillance of mutation carriers.

  18. this study reports the first patient affected by malignant paraganglioma and< moreover, it reports two more unrelated patients with the same genotype and very different clinical presentations.

  19. SDH deficiency may promote tumorigenesis through accumulation of succinate and inhibition of dioxygenase enzymes. Inhibition of TET activity may, in turn, alter global DNA methylation and gene expression in SDH-deficient tumors.

  20. Studies indicate that an array of tumor syndromes caused by complex II-associated mutations in genes SDHA, SDHB, SDHC, SDHD, SDHAF1 and SDHAF2 have been identified over a decade.

Cow (Bovine) Succinate Dehydrogenase Complex, Subunit C, Integral Membrane Protein, 15kDa (SDHC) interaction partners

  1. assignment to chromosome 2

SDHC 抗原简介

Antigen Summary

This gene encodes one of four nuclear-encoded subunits that comprise succinate dehydrogenase, also known as mitochondrial complex II, a key enzyme complex of the tricarboxylic acid cycle and aerobic respiratory chains of mitochondria. The encoded protein is one of two integral membrane proteins that anchor other subunits of the complex, which form the catalytic core, to the inner mitochondrial membrane. Several related pseudogenes are located in different genomic regions. Mutations in this gene have been associated with paragangliomas. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene names and symbols associated with SDHC

  • succinate dehydrogenase complex subunit C (SDHC) 抗体
  • succinate dehydrogenase complex subunit C (sdhc) 抗体
  • succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa (SdhC) 抗体
  • succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa (SDHC) 抗体
  • succinate dehydrogenase complex, subunit C, integral membrane protein (Sdhc) 抗体
  • succinate dehydrogenase complex subunit C (Sdhc) 抗体
  • 0610010E03Rik 抗体
  • AI316496 抗体
  • AU019277 抗体
  • CYB560 抗体
  • CYBL 抗体
  • PGL3 抗体
  • QPS1 抗体
  • SDH3 抗体
  • SDHC 抗体

Protein level used designations for SDHC

succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa , ENSANGP00000017418-like protein , OXPHOS complex II cytochrome B560 subunit , succinate dehydrogenase C , succinate dehydrogenase cytochrome b560 subunit, mitochondrial , QPs-1 , QPs1 , integral membrane protein CII-3 , succinate dehydrogenase complex, subunit C , cytochrome B large subunit of complex II , integral membrane protein CII-3b , succinate dehydrgenase cytochrome b , succinate dehydrogenase 3, integral membrane subunit , succinate-ubiquinone oxidoreductase cytochrome B large subunit , succinate dehydrogenase complex subunit C

GENE ID SPECIES
478983 Canis lupus familiaris
496650 Xenopus (Silurana) tropicalis
719978 Macaca mulatta
747462 Pan troglodytes
100114948 Nasonia vitripennis
100126849 Sus scrofa
66052 Mus musculus
289217 Rattus norvegicus
6391 Homo sapiens
327696 Bos taurus
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