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Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. 再加上，我们可以发SCNN1A 试剂盒 (13) 和 SCNN1A 蛋白 (7)和数多这个蛋白质的别的产品。
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Mouse (Murine) Polyclonal SCNN1A Primary Antibody for ICC, IF - ABIN863202
Jia, Liu, Sun, Kakizoe, Guan, Zhang, Zhou, Yang: mPGES-1-derived PGE2 mediates dehydration natriuresis. in American journal of physiology. Renal physiology 2013
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Hamster Polyclonal SCNN1A Primary Antibody for ICC, IF - ABIN863204
Gu: Effect of [Cl(-)]i on ENaC activity from mouse cortical collecting duct cells. in Journal of cellular physiology 2008
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Hamster Polyclonal SCNN1A Primary Antibody for ICC, IF - ABIN863203
Dyka, May, Enz: Subunits of the epithelial sodium channel family are differentially expressed in the retina of mice with ocular hypertension. in Journal of neurochemistry 2005
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Human Polyclonal SCNN1A Primary Antibody for FACS, ICC - ABIN261466
Williams, Chamarthi, Goodarzi, Pojoga, Sun, Garza, Raby, Adler, Hopkins, Brown, Jeunemaitre, Ferri, Fang, Leonor, Cui, Guo, Taylor, Ida Chen, Xiang, Raffel, Buchanan, Rotter, Williams, Shi: Lysine-specific demethylase 1: an epigenetic regulator of salt-sensitive hypertension. in American journal of hypertension 2012
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Human Polyclonal SCNN1A Primary Antibody for IF (p), IHC (p) - ABIN682243
Yamamoto, Hotta, Maeda, Kataoka, Maeda, Hamakawa, Sasaki, Yasui, Asai, Kimura: Mineralocorticoid receptor stimulation induces urinary storage dysfunction via upregulation of epithelial sodium channel expression in the rat urinary bladder epithelium. in Journal of pharmacological sciences 2016
mutation in the extracellular domain of alphaENaC causes Liddle syndrome by increasing intrinsic channel activity.
The mRNA and alpha-ENaC protein were overexpressed in platelets from hypertensive subjects versus control subjects.
The derlin-1 (显示 DERL1 抗体) pathway therefore may represent a significant early checkpoint in the recognition and degradation of ENaC in mammalian cells.
Data show that the expression of aquaporin (AQP) 1, AQP3, AQP5, epithelial Na+ channel (ENaC) and sodium potassium ATPase (Na-K-ATPase) are altered in patients with acute respiratory failure (ARF) due to diffuse alveolar damage (DAD), and the cause of DAD does not seem to influence the level of impairment of these channels.
The data indicate that the Lhs1 chaperone selectively recognizes an immature form of alphaENaC, one which has failed to correctly assemble with the other channel subunits via its transmembrane domain.
LEFTY2 (显示 LEFTY2 抗体) regulates the expression and activity of ENaC in endometrial epithelial cells via SGK1 (显示 SGK1 抗体).
Carriage of the p.W493R-SCNN1A polymorphism has been identified as a risk factor for bronchiectasis, but it is not invariably associated with the phenotype of a hyperactive ENaC channel in the lung.
although subgroup analysis showed alpha-ENaC T663A polymorphism was associated with essential hypertension in North American individuals, these meta-analysis results did not confirm such association overall; conclude that Alpha-ENaC T663A polymorphism might not be a risk factor for essential hypertension
Four nonsynonymous amino acid variants in SCNN1A in nonwhite Cystic fibrosis (显示 S100A8 抗体) patients with non-diagnostic CFTR (显示 CFTR 抗体) genotypes was identified.
The rs4149570 and rs7956915 polymorphisms of SCNN1A might play important roles in the susceptibility to respiratory distress syndrome, particularly in term infants.
ENaC activity is regulated by calpain-2 (显示 CAPN2 抗体) proteolysis of MARCKS (显示 MARCKS 抗体).
nonselective cation channels ( channels consist of at least one alpha-ENaC and one or more acid-sensing ion channel (显示 ACCN2 抗体) 1a (ASIC1a (显示 ACCN2 抗体)) proteins.
ENaC and ROMK (显示 KCNJ1 抗体) channel activity in kidney tubules are inhibited in TgWnk4(pseudoaldosteronism type II) mice. Wnk4 (显示 WNK4 抗体)(PHAII)-induced inhibition of ENaC and ROMK (显示 KCNJ1 抗体) may contribute to the suppression of K(+) secretion in the tubules.
Exosomal GAPDH (显示 GAPDH 抗体) from Proximal Tubule Cells Regulate ENaC Activity
depletion of Kir4.1 (显示 KCNJ10 抗体) stimulates the expression of ENaCbeta (显示 SCNN1B 抗体) and -gamma subunits in the cortical collecting duct
reducing ENaC expression in the connecting tubule induces clear pseudohypoaldosteronism type 1 symptoms during high dietary potassium loading
The findings demonstrated a substantial role of mitochondrial dysfunction in mediating the downregulation of NKCC2 (显示 SLC12A1 抗体) and ENaCalpha in obstructive kidney disease, possibly via iNOS (显示 NOS2 抗体)-derived nitric oxide and BNP (显示 BNC2 抗体).
PCSK9 (显示 PCSK9 抗体)(-/-) mice display normal sodium balance and blood pressure regulation despite an increase of cleaved alphaENaC under basal condition
Different subunits of ENaC expressed in various cell regions of the cochlea and endolymphatic sac (显示 ADCY10 抗体) in distinct patterns may form the functional sodium channel to regulate the endolymph and maintain homeostasis in inner ear.
Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
, amiloride-sensitive sodium channel subunit alpha
, epithelial Na(+) channel subunit alpha
, epithelial sodium channel alpha subunit
, nonvoltage-gated sodium channel 1 subunit alpha
, sodium channel, nonvoltage-gated, type I, alpha
, alpha ENaC-2
, amiloride-sensitive epithelial sodium channel alpha subunit
, amiloride-sensitive sodium channel subunit alpha 2
, nasal epithelial sodium channel alpha subunit
, sodium channel, nonvoltage-gated 1 alpha
, ENaC alpha
, amiloride-sensitive epithelial sodium channel
, sodium channel, nonvoltage-gated, type I, alpha polypeptide
, alpha ENaC
, epithelial sodium channel ENaC alpha subunit
, alpha cENaC 431
, amiloride-sensitve epithelial sodium channel alpha subunit
, alpha-subunit renal epithelial sodium channel
, epithelium sodium channel alpha subunit
, sodium channel, nonvoltage-gated 1, alpha
, amiloride-sensitive sodium channel alpha subunit