SCNN1A 抗体 (AA 617-638) (PE)
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Quick Overview for SCNN1A 抗体 (AA 617-638) (PE) (ABIN2486415)
抗原
See all SCNN1A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 617-638
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特异性
- Detects ~87 kDa.
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交叉反应
- Hamster, 人, 小鼠, 大鼠, 非洲爪蟾
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纯化方法
- Protein A Purified
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免疫原
- Produced against the C-terminal tail (amino acids 617-638) of rat beta ENaC (antibody designation 3755-2)
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anti-Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A) (AA 617-638) antibody
SCNN1A 适用: 大鼠 WB, IHC, IP, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A) (AA 629-650) antibodySCNN1A 适用: 大鼠 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A) (AA 46-68) antibodySCNN1A 适用: 大鼠 WB, IHC, IP, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A) (AA 201-300) antibodySCNN1A 适用: 大鼠, 人, 小鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A) (AA 617-638) antibody (HRP)SCNN1A 适用: 大鼠 WB, IHC, IP, ICC, IF 宿主: 兔 Polyclonal HRP
anti-Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A) (AA 617-638) antibody (FITC)SCNN1A 适用: 大鼠 WB, IHC, IP, ICC, IF 宿主: 兔 Polyclonal FITC
anti-Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A) (AA 617-638) antibody (Biotin)SCNN1A 适用: 大鼠 WB, IHC, IP, ICC, IF 宿主: 兔 Polyclonal Biotin
anti-Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A) (AA 617-638) antibody (PerCP)SCNN1A 适用: 大鼠 WB, IHC, IP, ICC, IF 宿主: 兔 Polyclonal PerCP
anti-Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A) (AA 617-638) antibody (APC)SCNN1A 适用: 大鼠 WB, IHC, IP, ICC, IF 宿主: 兔 Polyclonal APC
anti-Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A) (AA 617-638) antibody (Atto 488)SCNN1A 适用: 大鼠 WB, IHC, IP, ICC, IF 宿主: 兔 Polyclonal Atto 488
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应用备注
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- WB (1:1000)
- IHC (1:100)
- optimal dilutions for assays should be determined by the user.
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说明
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1 μg/ml of ABIN2486415 was sufficient for detection of beta-ENaC in 20 μg of rat kidney tissue lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Conjugated antibodies should be stored at 4°C
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- SCNN1A (Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A))
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别名
- ENaC
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背景
- The Epithelial Sodium Channel (ENaC) is a membrane ion channel permeable to Na+ ions. It is located in the apical plasma membrane of epithelia in the kidneys, lung, colon, and other tissues where it plays a role in trans epithelial Na+-ion transport (1). Specifically Na+ transport via ENaC occurs across many epithelial surfaces, and plays a key role in regulating salt and water absorption (2). ENaCs are composed of three structurally related subunits that form a tetrameric channel, α, β, and γ. The expression of its alpha and beta subunits is enhanced as keratinocytes differentiate (3, 4). The beta and gamma-ENaC subunits are essential for edema fluid to exert its maximal effect on net fluid absorption by distal lung epithelia(5). And it has been concluded that the subunits are differentially expressed in the retina of mice with ocular hypertension, therefore the up-regulation of alpha-ENaC proteins could serve as a protection mechanism against elevated intraocular pressure (6).
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基因ID
- 24767
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NCBI登录号
- NP_036780
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UniProt
- P37090
抗原
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