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SCNN1A 抗体 (AA 201-300)

This 兔 多克隆 antibody specifically detects SCNN1A in WB, ELISA, FACS, IHC (p), IF (cc), IF (p) 和 IHC (fro). It exhibits reactivity toward 大鼠, 人 和 小鼠. It has been mentioned in 3+ publications
产品编号 ABIN682243
发货至: 中国
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Quick Overview for SCNN1A 抗体 (AA 201-300) (ABIN682243)

抗原

See all SCNN1A 抗体
SCNN1A (Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A))

适用

  • 96
  • 43
  • 37
  • 20
  • 10
大鼠, 人, 小鼠

宿主

  • 83
  • 41

克隆类型

  • 83
  • 41
多克隆

标记

  • 31
  • 11
  • 10
  • 10
  • 10
  • 10
  • 9
  • 9
  • 9
  • 9
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SCNN1A antibody is un-conjugated

应用范围

  • 114
  • 103
  • 36
  • 35
  • 31
  • 21
  • 11
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 60
    • 22
    • 20
    • 10
    • 10
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 201-300

    交叉反应

    人, 小鼠, 大鼠

    预测反应

    Dog,Cow,Sheep,Pig,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Alpha-ENaC

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Scortegagna, Berthon, Settas, Giannakou, Garcia, Li, James, Liddington, Vilches-Moure, Stratakis, Ronai: "The E3 ubiquitin ligase Siah1 regulates adrenal gland organization and aldosterone secretion." in: JCI insight, Vol. 2, Issue 23, (2019) (PubMed).

    Yamamoto, Hotta, Maeda, Kataoka, Maeda, Hamakawa, Sasaki, Yasui, Asai, Kimura: "Mineralocorticoid receptor stimulation induces urinary storage dysfunction via upregulation of epithelial sodium channel expression in the rat urinary bladder epithelium." in: Journal of pharmacological sciences, Vol. 130, Issue 4, pp. 219-25, (2016) (PubMed).

  • 抗原

    SCNN1A (Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A))

    别名

    Alpha-ENaC

    背景

    Synonyms: BESC2, ENaCa, SCNEA, SCNN1, ENaCalpha, Amiloride-sensitive sodium channel subunit alpha, Alpha-NaCH, Epithelial Na(+) channel subunit alpha, Alpha-ENaC, Nonvoltage-gated sodium channel 1 subunit alpha, SCNN1A

    Background: Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.

    基因ID

    6337

    UniProt

    P37088
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