SCN1A 抗体
(Sodium Channel, Voltage-Gated, Type I, alpha Subunit (SCN1A))
The vertebrate sodium channel is a voltage-gated ion channel essential for the generation and propagation of action potentials, mainly in nerve and muscle. Voltage-sensitive sodium channels are heteromeric complexes consisting of a large central pore-forming glycosylated alpha subunit, and two smaller auxiliary beta subunits. This gene encodes the large alpha subunit, and mutations in this gene have been associated with several epilepsy, convulsion and migraine disorders. Alternative splicing results in multiple transcript variants. The RefSeq Project has decided to create four representative RefSeq records. Three of the transcript variants are supported by experimental evidence and the fourth contains alternate 5' untranslated exons, the exact combination of which have not been experimentally confirmed for the full-length transcript.[provided by RefSeq, Jan 2011].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| SCN1A 抗体 (Intracellular) | 大鼠 | 兔 Polyclonal |
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| SCN1A 抗体 (AA 481-515) | 人 | 兔 Polyclonal |
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| SCN1A 抗体 | 人, 大鼠 | 兔 Polyclonal |
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| SCN1A 抗体 (Extracellular, Loop 3) | 小鼠 | 兔 Polyclonal |
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| SCN1A 抗体 (Internal Region) | 人 | 兔 Polyclonal |
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| SCN1A 抗体 (AA 1901-2009) | 人 | 兔 Polyclonal |
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| Recombinant SCN1A 抗体 | – | 小鼠 Monoclonal |
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| SCN1A 抗体 (AA 274-399) | 人 | 兔 Polyclonal |
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| SCN1A 抗体 | 人, 大鼠 | 兔 Polyclonal |
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| SCN1A 抗体 | 人 | 小鼠 Monoclonal |
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| SCN1A 抗体 (AA 33-82) | 人, 大鼠, 小鼠 | 兔 Polyclonal |
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| SCN1A 抗体 (C-Term) | 人, 大鼠, 小鼠 | 兔 Polyclonal |
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| SCN1A 抗体 (Intracellular) (Atto 594) | 大鼠 | 兔 Polyclonal |
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| SCN1A 抗体 (Intracellular) | 大鼠 | 豚鼠 Polyclonal |
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| SCN1A 抗体 (Center) | 人, 大鼠, 小鼠 | 兔 Polyclonal |
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| Rockland Original | SCN1A 抗体 (C-Term) | 大鼠 | 小鼠 Monoclonal |
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| SCN1A 抗体 (Extracellular, Loop 3) | 人, 大鼠, 小鼠 | 兔 Polyclonal |
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| SCN1A 抗体 (N-Term) | 人 | 兔 Polyclonal |
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| SCN1A 抗体 | 人, 大鼠, 小鼠 | 兔 Polyclonal |
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| SCN1A 抗体 (C-Term) (APC) | 人, 大鼠, 小鼠 | 兔 Polyclonal |
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Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- WB (Western Blotting: 有验证图片)
- M (Molecule: 有验证图片)
- ICC (Immunocytochemistry: 有验证图片)
- IF (Immunofluorescence: 所列应用)
- IP (Immunoprecipitation: 所列应用)
- IC (Immunochromatography: 所列应用)
KO 验证
- 质量等级
- KO Validated
- 适用
- 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 465-481, Intracellular
Primary Antibody
- WB (Western Blotting: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB57630
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 481-515
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- WB (Western Blotting: 有验证图片)
- M (Molecule: 有验证图片)
- 适用
- 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 311-324, Extracellular, Loop 3
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- Internal Region
Primary Antibody
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1901-2009
Primary Antibody
- IHC (Immunohistochemistry: 所列应用)
- WB (Western Blotting: 所列应用)
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- K74-53
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG2a, kappa
Primary Antibody
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 274-399
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 大鼠, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 33-82
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人, 大鼠, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- C-Term
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- M (Molecule: 有验证图片)
- IF (Immunofluorescence: 所列应用)
KO 验证
- 质量等级
- KO Validated
- 适用
- 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Atto 594
- 抗体亚型
- IgG
- 抗原表位
- AA 465-481, Intracellular
Primary Antibody
- WB (Western Blotting: 有验证图片)
- M (Molecule: 有验证图片)
- 适用
- 大鼠
- 宿主
- 豚鼠
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 465-481, Intracellular
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- WB (Western Blotting: 有验证图片)
- 适用
- 人, 大鼠, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- Center
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- WB (Western Blotting: 所列应用)
- IP (Immunoprecipitation: 所列应用)
- FM (Fluorescence Microscopy: 所列应用)
- Supplier Product No.
- Rockland 200-301-g18
- 适用
- 大鼠
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- S74-71
- 标记
- unconjugated
- 抗体亚型
- IgG1
- 抗原表位
- C-Term
Rockland Original
Primary Antibody
- M (Molecule: 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- WB (Western Blotting: 所列应用)
- 质量等级
- Carrier-free
- 适用
- 人, 大鼠, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 311-324, Extracellular, Loop 3
Primary Antibody
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- WB (Western Blotting: 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- EIA (Enzyme Immunoassay: 所列应用)
- 适用
- 人, 大鼠, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 人, 大鼠, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- APC
- 抗体亚型
- IgG
- 抗原表位
- C-Term
Latest Publications for our SCN1A 抗体
: "Sodium channel β1 subunit localizes to axon initial segments of excitatory and inhibitory neurons and shows regional heterogeneity in mouse brain." in: The Journal of comparative neurology, Vol. 523, Issue 5, pp. 814-30, (2015) (PubMed).
: "Acceleration of conduction velocity linked to clustering of nodal components precedes myelination." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 3, pp. E321-8, (2015) (PubMed).
: "Molecular identity of axonal sodium channels in human cortical pyramidal cells." in: Frontiers in cellular neuroscience, Vol. 8, pp. 297, (2014) (PubMed).
: "Action potential initiation in neocortical inhibitory interneurons." in: PLoS biology, Vol. 12, Issue 9, pp. e1001944, (2014) (PubMed).
: "Altered sleep regulation in a mouse model of SCN1A-derived genetic epilepsy with febrile seizures plus (GEFS+)." in: Epilepsia, Vol. 54, Issue 4, pp. 625-34, (2013) (PubMed).
: "FGF14 localization and organization of the axon initial segment." in: Molecular and cellular neurosciences, Vol. 56, pp. 393-403, (2013) (PubMed).
: "Interaction between the transcriptional corepressor Sin3B and voltage-gated sodium channels modulates functional channel expression." in: Scientific reports, Vol. 3, pp. 2809, (2013) (PubMed).
: "NaV1.1 channels in axon initial segments of bipolar cells augment input to magnocellular visual pathways in the primate retina." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 41, pp. 16045-59, (2013) (PubMed).
: "Changes in the physiology of CA1 hippocampal pyramidal neurons in preplaque CRND8 mice." in: Neurobiology of aging, Vol. 33, Issue 8, pp. 1609-23, (2012) (PubMed).
: "Reduced sodium channel Na(v)1.1 levels in BACE1-null mice." in: The Journal of biological chemistry, Vol. 286, Issue 10, pp. 8106-16, (2011) (PubMed).
: "Acceleration of conduction velocity linked to clustering of nodal components precedes myelination." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 3, pp. E321-8, (2015) (PubMed).
: "Molecular identity of axonal sodium channels in human cortical pyramidal cells." in: Frontiers in cellular neuroscience, Vol. 8, pp. 297, (2014) (PubMed).
: "Action potential initiation in neocortical inhibitory interneurons." in: PLoS biology, Vol. 12, Issue 9, pp. e1001944, (2014) (PubMed).
: "Altered sleep regulation in a mouse model of SCN1A-derived genetic epilepsy with febrile seizures plus (GEFS+)." in: Epilepsia, Vol. 54, Issue 4, pp. 625-34, (2013) (PubMed).
: "FGF14 localization and organization of the axon initial segment." in: Molecular and cellular neurosciences, Vol. 56, pp. 393-403, (2013) (PubMed).
: "Interaction between the transcriptional corepressor Sin3B and voltage-gated sodium channels modulates functional channel expression." in: Scientific reports, Vol. 3, pp. 2809, (2013) (PubMed).
: "NaV1.1 channels in axon initial segments of bipolar cells augment input to magnocellular visual pathways in the primate retina." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 41, pp. 16045-59, (2013) (PubMed).
: "Changes in the physiology of CA1 hippocampal pyramidal neurons in preplaque CRND8 mice." in: Neurobiology of aging, Vol. 33, Issue 8, pp. 1609-23, (2012) (PubMed).
: "Reduced sodium channel Na(v)1.1 levels in BACE1-null mice." in: The Journal of biological chemistry, Vol. 286, Issue 10, pp. 8106-16, (2011) (PubMed).
Aliases for SCN1A 抗体
sodium voltage-gated channel alpha subunit 1 (SCN1A) 抗体sodium voltage-gated channel alpha subunit 9 (SCN9A) 抗体
sodium channel, voltage-gated, type I, alpha (Scn1a) 抗体
sodium voltage-gated channel alpha subunit 1 (Scn1a) 抗体
B230332M13 抗体
EIEE6 抗体
FEB3 抗体
FEB3A 抗体
FHM3 抗体
GEFSP2 抗体
HBSCI 抗体
NAC1 抗体
Nav1.1 抗体
SCN1 抗体
SCN1A 抗体
SCN9A 抗体
SMEI 抗体
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