Siglece 抗体
(Sialic Acid Binding Ig-Like Lectin E (Siglece))
Putative adhesion molecule that mediates sialic-acid dependent binding to cells. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules.
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Latest Publications for our Siglece 抗体
: "MYC-driven synthesis of Siglec ligands is a glycoimmune checkpoint." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 120, Issue 11, pp. e2215376120, (2023) (PubMed).: "Siglec-7 restores β-cell function and survival and reduces inflammation in pancreatic islets from patients with diabetes." in: Scientific reports, Vol. 7, pp. 45319, (2017) (PubMed).
: "Siglec-E Negatively Regulates the Activation of TLR4 by Controlling Its Endocytosis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 197, Issue 8, pp. 3336-3347, (2016) (PubMed).
Aliases for Siglece 抗体
sialic acid binding Ig-like lectin E (Siglece) 抗体Cd170 抗体
mSiglec-E 抗体
Siglec5 抗体
Siglec9 抗体
Siglec12 抗体
Siglecl1 抗体
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- SIGLEC9 抗体
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- SIGLEC5 抗体
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