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RFX3 is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. 再加上，我们可以发RFX3 抗体 (56) 和 RFX3 蛋白 (4)和数多这个蛋白质的别的产品。
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RFX3 interacts with the D sequence of adeno-associated virus inverted terminal repeat and regulates AAV transduction.
findings reveal a regulation of RFX3 transcription factor and link fatty acid metabolism and protein lipidation to the regulation of ciliogenesis.
FOXJ1 is an important regulator of cilia gene expression during ciliated cell differentiation, with RFX3 as a transcriptional co-activator to FOXJ1.
Taken together, this study suggests ciliogenic RFX transcription factors regulate FGF-1B promoter activity and the maintenance of F1BGFP(+) NSPCs and GBM-SCs.
Data show that two regulatory factor for X box (RFX1 and 3) binding sites in exon1 of both the mouse and human microtubule-associated protein (MAP1A) gene are important for effective transcriptional repression in non-neuronal cells.
novel role for the RFX family of transcription factors as modulators of Ras signalling in epithelial cells.
RFX3 controls the expression of genes involved in primary ciliary dyskinesia.
The ciliogenic transcription factor Rfx3 is required for the formation of the thalamocortical tract by regulating the patterning of prethalamus and ventral telencephalon
This study unravels a crucial role of RFX3 during early brain development by indirectly regulating GLI3 activity, which leads to FGF8 upregulation and ultimately to disturbed distribution of guidepost neurons required for CC morphogenesis
High dosage of resveratrol pretreatment inhibited the injury-induced up-regulation of eIF2alpha-CHOP and IRE1alpha-XBP1 pathways.
Rfx3 is required for the differentiation and function of mature beta-cells and regulates the beta-cell promoter of the glucokinase gene.
RFX3 may play roles in haploid cells during mouse spermatogenesis
RFX3 is essential for the differentiation of nodal monocilia and hence for LR body axis determination.
These results demonstrate that regulatory factor X3 is necessary for ciliated ependymal cell differentiation in the mouse.
RFX3 participates in the mechanisms that govern pancreatic endocrine cell differentiation and the presence of primary cilia on islet cells may play a key role in this process.
RFX3 is also necessary for biogenesis of motile cilia.
This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. Two transcript variants encoding different isoforms have been described for this gene, and at least one of the variants utilizes alternative polyadenylation signals.
regulatory factor X3
, transcription factor RFX3
, DNA binding protein RFX3
, regulatory factor X 3