anti-Purine-Rich Element Binding Protein A (PURA) 抗体

PURA product is a sequence-specific, single-stranded DNA-binding protein. 再加上,我们可以发PURA 蛋白 (7)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
PURA 19290 P42669
PURA 307498  
PURA 5813 Q00577
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antibodies-online.cn销售最多的anti-PURA 抗体

Showing 10 out of 52 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 WB Host:  Rabbit  Target Name:  PURA  Sample Tissue:  Human THP-1 Whole Cell lysates  Antibody Dilution:  1ug/ml 100 μL Log in to see 2至3个工作日
$289.00
详细
Cow 非结合性 IHC, WB Immunohistochemistry with Brain, cerebellum tissue at an antibody concentration of 5µg/ml using anti-PURA antibody (ARP33202_P050) WB Suggested Anti-PURA Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  MCF7 cell lysate PURA is strongly supported by BioGPS gene expression data to be expressed in Human MCF7 cells 100 μL Log in to see 2至3个工作日
$289.00
详细
Cow 非结合性 WB WB Suggested Anti-PURA Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:1562500  Positive Control:  HepG2 cell lysate 100 μL Log in to see 2至3个工作日
$289.00
详细
Cow 非结合性 WB WB Suggested Anti-Pura Antibody   Titration: 1.0 ug/ml   Positive Control: Mouse Thymus 100 μL Log in to see 2至3个工作日
$289.00
详细
小鼠 非结合性 ELISA, IF, WB Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.84 KDa) . Dilution: 1:500~1000 PURA monoclonal antibody (M02), clone 1C10. Western Blot analysis of PURA expression in PC-12 ( (# ABIN394014 ) Dilution: 1:500~1000 100 μg Log in to see 8至11个工作日
$527.50
详细
Bat 非结合性 IHC, IHC (p), WB Anti-PURA antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN958320 concentration 5 ug/ml. Anti-PURA antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. ... 50 μg Log in to see 11至14个工作日
$727.83
详细
Cow 非结合性 WB 50 μg Log in to see 11至14个工作日
$551.83
详细
非结合性 IHC (p), WB PURA Antibody (C-term) (ABIN1881707) western blot analysis in A549,NCI-H292 cell line lysates (35 µg/lane). This demonstrates the PURA antibody detected the PURA protein (arrow). PURA Antibody (C-term) (ABIN1881707) western blot analysis in A549,NCI-H292 cell line lysates (35 µg/lane). This demonstrates the PURA antibody detected the PURA protein (arrow). 400 μL Log in to see 10至11个工作日
$385.00
详细
非结合性 WB Western Blot: PURA Antibody [NBP2-20012] - Sample (30 ug of whole cell lysate) A: NT2D1 10% SDS PAGE gel, diluted at 1:500. Western Blot: PURA Antibody [NBP2-20012] - Sample (50 ug of whole cell lysate) A: Mouse Brain, 10% SDS PAGE gel, diluted at 1:1000. 0.1 mL Log in to see 8至11个工作日
$516.98
详细
Bat 非结合性 WB 50 μg Log in to see 11至14个工作日
$551.83
详细

引用最多的anti-PURA 抗体

  1. Human Polyclonal PURA Primary Antibody for IHC (p), WB - ABIN1881707 : Gazla, Carracedo: Effect of intracellular Wolbachia on interspecific crosses between Drosophila melanogaster and Drosophila simulans. in Genetics and molecular research : GMR 2009 (PubMed)
    Show all 5 Pubmed References

更多抗PURA的相互作用对抗体

Mouse (Murine) Purine-Rich Element Binding Protein A (PURA) interaction partners

  1. Quantitative immunohistochemical assays of the vermal region of the cerebellum and CA1-3 regions of the hippocampus revealed reduced numbers of neurons in general, as well as reduced numbers of Pur-alpha+-immunopositive neurons and dendrites in heterozygous Pur-alpha mice, compared to wild-type littermates

  2. This study underlines the importance of Puralpha in the proliferation of neuronal precursor cells during postnatal brain development and suggest a role for Puralpha in the regulation of the expression and cellular distribution of dendritic and axonal proteins.

  3. Data suggest that Puralpha has a role in nucleotide excision repair and the repair of UVC-induced DNA damage.

  4. Overexpression of Purbeta, but not Puralpha, significantly downregulated GnRH1 mRNA Levels in transiently transfected GT1-7 cells, suggesting that Purbeta acts as a repressor of GnRH1 gene transcription.

  5. Identification of mrna/protein (mRNA) complexes and their association with rough endoplasmic reticulum equipped with a kinesin motor

  6. Pura is essential for postnatal brain development and developmentally coupled cellular proliferation as revealed by genetic inactivation.

  7. we also determined a region in Pur alpha which is required for the association with the purine rich element binding protein by using deletion mutants of Pur alpha

  8. Puralpha has been shown to colocalize with cyclin A/Cdk2 and to coimmunoprecipitate with cyclin A during S-phase and we show that this interaction is mediated by a specific affinity of Puralpha for Cdk2.

  9. analysis of of DNA binding and localized strand separation by Pur alpha and comparison with Pur beta

  10. Pur alpha and Pur beta repress smooth muscle alpha-actin gene transcription by means of DNA strand-selective cis-element binding and cell type-dependent protein-protein interactions

  11. E2F-1 and Puralpha interplay appears to be involved in the regulation of Puralpha expression and the cell cycle.

  12. These data demonstrate that Pur proteins collaborate with Sp3 to regulate a transcriptional program that enables muscle cells to remodel their phenotype.

  13. Activation of the normally silent SM alpha A gene in reprogrammed adult cardiomyocytes is linked to elevated interaction of serum response factor with Pur-alpha/Pur-beta.

  14. Expression patterns suggest an accessory role of C9orf10 for Puralpha in a limited brain region in addition to other possible functions that have not yet been determined.

  15. Tat stimulates the Rad51 promoter involving both Puralpha-dependent and Puralpha-independent mechanisms. Interaction between Puralpha and Tat may have opposing effects on Rad51 expression.

  16. analysis of how a bifunctional intronic element regulates the expression of the arginine/lysine transporter Cat-1 via mechanisms involving the purine-rich element binding protein A (Pur alpha)

Human Purine-Rich Element Binding Protein A (PURA) interaction partners

  1. Three genes in our epilepsy cohort (COQ4, DNM1, and PURA), accounting for 14% (3/21) of all novel genetic etiologies identified in patients with epilepsy, were subsequently confirmed in independent publications.

  2. PURA may be a potential target of miR-144 and observed downregulation of PURA may be caused by increased expression of miR-144. The other predicted target of miR-144 SPRED1, was found to be downregulated in 69 per cent EC tissues as compared to matched distant non-malignant tissues.

  3. The results of this study emphasizes the importance of stress granules in ALS pathogenesis and identifies Pur-alpha as a novel regulator of cytoplasmic stress granules dynamics.

  4. These findings provide definitive evidence for the role of PURA in causing a variable syndrome of neurodevelopmental delay, learning disability, neonatal hypotonia, feeding difficulties, abnormal movements and epilepsy in humans

  5. Mutations in PURA cause profound neonatal hypotonia, seizures, and encephalopathy in 5q31.3 microdeletion syndrome.

  6. Data show that protein PURalpha is specifically involved in the transcriptional activation of the secondary promoter and may exert its function by forming a complex with E2F-1 and RNA polymerase II.

  7. Suggest dynamic interplay between transcriptional activators Pur-alpha/Pur-beta and repressors in regulating SMalphaA gene output during myofibroblast differentiation.

  8. This study showed that Pur-alpha showed inadequate expression in monocytes, and the translation of Pur-alpha mRNA was repressed by cell-expressed microRNA.

  9. The study identifies three functionally distinct PURA promoters and show that these are utilized differentially in human cell types and that they respond differently to cytomegalovirus infection.

  10. The ability of Puralpha to activate the CD11c gene promoter increases in differentiating U937 monocytic cells.

  11. acts together with hnRNP-K to repress the transcriptional activity of the CD43 gene promoter during lymphocyte activation

  12. results show that PUR proteins are capable of binding to alpha-MHC mRNA and attenuate its translational efficiency; also show robust expression of PUR proteins in failing hearts where alpha-MHC mRNA levels are suppressed

  13. The N-terminal 72 amino acids of Pura were involved in E2F-1 binding, inhibition of promoter activation by E2F-1 and reversal of E2F-mediated growth inhibition.

  14. Puralpha has been shown to colocalize with cyclin A/Cdk2 and to coimmunoprecipitate with cyclin A during S-phase and we show that this interaction is mediated by a specific affinity of Puralpha for Cdk2.

  15. Hypoxia induces a coordinated up-regulation in beta2 integrin expression that is dependent upon transcriptional mechanisms mediated by HIF-1 and Pur alpha.

  16. the partnership of Puralpha with Rev is beneficial for Rev-mediated expression of the HIV-1 genome.

  17. that the recruitment of YB1, PURalpha, and H1.2 to the p53 target gene Bax is required for repression of p53-induced transcription.

  18. Stably overexpressing PURalpha in PC3 and DU145 cells negatively regulates cell proliferation, resulting in decreases in PCNA expression

  19. A transcriptional repressor complex that binds a specific sequence (repressor element) in the androgen recptor gene 5'-untranslated region in prostate cancer contains Pur alpha.

  20. Pur-alpha protein is associated with Alzheimer's disease.

Zebrafish Purine-Rich Element Binding Protein A (PURA) interaction partners

  1. repressor of gata2 gene expression in the nervous system

PURA 抗原简介

蛋白简介

This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia.

Gene names and symbols associated with PURA

  • purine-rich element binding protein A (pura) 抗体
  • purine rich element binding protein A (Pura) 抗体
  • purine rich element binding protein A (PURA) 抗体
  • purine-rich element binding protein Aa (puraa) 抗体
  • purine-rich element binding protein A L homeolog (pura.L) 抗体
  • CAGER-1 抗体
  • pur-alpha 抗体
  • pur1 抗体
  • puralpha 抗体
  • ssCRE-BP 抗体
  • zgc:103411 抗体

Protein level used designations for PURA

purine-rich element binding protein A , Pur alpha , purine-rich single-stranded DNA-binding protein alpha , transcriptional activator protein Pur-alpha , pur-alpha

GENE ID SPECIES
100135162 Xenopus (Silurana) tropicalis
19290 Mus musculus
307498 Rattus norvegicus
5813 Homo sapiens
487159 Canis lupus familiaris
782746 Bos taurus
415106 Danio rerio
446744 Xenopus laevis
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