anti-Protein Arginine Methyltransferase 6 (PRMT6) 抗体

The protein encoded by PRMT6 belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated a. 再加上,我们可以发Protein Arginine Methyltransferase 6 蛋白 (11)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
PRMT6 55170 Q96LA8
PRMT6 295384  
PRMT6 99890 Q6NZB1
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antibodies-online.cn销售最多的anti-Protein Arginine Methyltransferase 6 抗体

Showing 10 out of 115 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 交付 价格 详细
Cow 非结合性 ChIP, WB WB Suggested Anti-PRMT6 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:1562500  Positive Control:  293T cell lysate Quiescent human colon carcinoma HCT116 cultures were treated with 10% FBS for three time points (0, 15, 30min) or (0, 30, 60min) were used in Matrix-ChIP and real-time PCR assays at EGR1 gene (Exon1) and 15kb upstream site. 100 μL 2至3个工作日
$289.00
详细
Cow 非结合性 WB WB Suggested Anti-Prmt6 Antibody Titration: 1.0 ug/ml Positive Control: Rat Muscle 100 μL 2至3个工作日
$289.00
详细
非结合性 WB 100 μg 2至3个工作日
$245.00
详细
小鼠 非结合性 ELISA, WB 100 μL 14至16个工作日
$247.82
详细
山羊 非结合性 ELISA, WB   100 μg 6至7个工作日
$429.84
详细
非结合性 EIA, IHC (p), WB 0.4 mL 6至8个工作日
$484.00
详细
非结合性 IP, WB 100 μL 14至16个工作日
$247.82
详细
非结合性 IHC, IHC (p), WB Human Breast (formalin-fixed, paraffin-embedded) stained with PRMT6 antibody ABIN218313 at 1:100 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-PRMT6 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100. 50 μL 11至14个工作日
$484.00
详细
豚鼠 山羊 非结合性 ELISA, WB 100 μg 11至14个工作日
$610.50
详细
非结合性 WB 100 μL 11至14个工作日
$551.83
详细

引用最多的anti-Protein Arginine Methyltransferase 6 抗体

  1. Human Polyclonal PRMT6 Primary Antibody for WB - ABIN4347359 : Herrmann, Bossert, Schwander, Akgün, Fackelmayer: Arginine methylation of scaffold attachment factor A by heterogeneous nuclear ribonucleoprotein particle-associated PRMT1. in The Journal of biological chemistry 2004 (PubMed)
    Show all 18 Pubmed References

  2. Human Polyclonal PRMT6 Primary Antibody for IHC (p), ELISA - ABIN543138 : Rho, Choi, Seong, Cho, Kim, Im: Prmt5, which forms distinct homo-oligomers, is a member of the protein-arginine methyltransferase family. in The Journal of biological chemistry 2001 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal PRMT6 Primary Antibody for ICC, IF - ABIN258292 : Mitchell, Glenfield, Jeyanthan, Zhu: Arginine methylation regulates telomere length and stability. in Molecular and cellular biology 2009 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal PRMT6 Primary Antibody for IHC (p), IHC - ABIN258293 : Iberg, Espejo, Cheng, Kim, Michaud-Levesque, Richard, Bedford: Arginine methylation of the histone H3 tail impedes effector binding. in The Journal of biological chemistry 2008 (PubMed)
    Show all 2 Pubmed References

  5. Human Monoclonal PRMT6 Primary Antibody for ELISA, WB - ABIN966895 : Maruyama, Sugano: Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. in Gene 1994 (PubMed)
    Show all 3 Pubmed References

  6. Human Polyclonal PRMT6 Primary Antibody for ELISA, WB - ABIN4347361 : Michaud-Levesque, Richard: Thrombospondin-1 is a transcriptional repression target of PRMT6. in The Journal of biological chemistry 2009 (PubMed)

更多抗Protein Arginine Methyltransferase 6的相互作用对抗体

Human Protein Arginine Methyltransferase 6 (PRMT6) interaction partners

  1. H3R2me2as is a strong prognostic indicator of gastric cancer (GC) patients, and PRMT6-overexpressing GC cells may acquire invasiveness through direct transcriptional inhibition of PCDH7 by increasing H3R2me2as level.

  2. Loss of PPARalpha from the intestine promotes colon carcinogenesis by increasing DNMT1/PRMT6-mediated DNA methylation.

  3. Our data reveal that PRMT6 plays a role in the control of erythroid/megakaryocytic differentiation and open up the possibility that manipulation of PRMT6 activity could facilitate enhanced erythropoiesis for therapeutic use.

  4. PRMT6 is physically associated with PTEN, promotes asymmetrical dimethylation of PTEN, and regulates the PI3K-AKT cascade through PTEN R159 methylation.

  5. This study indicated that the hypomethylation of PRMT6 promoter could be a novel diagnostic biomarker for colorectal cancer.

  6. PRMT6 negatively regulates DNA methylation in cancer. PRMT6 overexpression impairs chromatin association of UHRF1, an accessory factor of DNMT1, resulting in passive DNA demethylation.

  7. Data suggest that histone-arginine N-methyltransferase PRMT6 (PRMT6) plays an oncogenic role in prostate cancer (PCa) and predicts for more clinically aggressive disease, constituting a potential target for patients with Prostate cancer (CRPC).

  8. Based on the structural information here and available in the PDB database, we proposed a mechanism that can rationalize the distinctive arginine methylation product specificity of different types of arginine methyltransferases and pinpoint the structural determinant of such a specificity

  9. PRMT6, which was down-regulated by androgen receptors and influenced cell migration and apoptosis of germ cells, could play a potentially important role in spermatogenesis.

  10. PRMT6 methylates tumor cell p21 at arginine 156 and promotes phosphorylation of threonine 145 on p21, increasing the cytoplasmic localization of p21 and inducing resistance to anticancer drugs.

  11. PRMT6 influences PRC-mediated gene silencing at the rostral HOXA genes locus.

  12. Data show that HIV-1 Tat methylation by protein arginine methyltransferase 6 (PRMT6) can inhibit nucleolar retention.

  13. N terminus is methylated by PRMT6 and that this critically affects the functions of pUL69 for efficient mRNA export and replication of human cytomegalovirus.

  14. TBL1 is required to protect GPS2 from degradation, with methylation of GPS2 by arginine methyltransferase PRMT6 regulating the interaction with TBL1 and inhibiting proteasome-dependent degradation.

  15. PRMT6 mediates cigarette smoke extract induced apoptosis and inflammation through H3R2me2a in HUVECs.

  16. PRMT6 specifically interacts with ERalpha at its ligand-binding domain.

  17. Authors show that PRMT6 requires the activation domain, but surprisingly not the basic domain, of HIV-1 Tat for protein interaction.

  18. Data show arginine methyltransferase PRMT6 methylates the AT-hook motif of regulatory factor RFX5 and downregulates HLA-DQ expression.

  19. Arginine 42 of histone H3 (H3R42), is dimethylated by the methyltransferases coactivator arginine methyltransferase 1 (CARM1) and protein arginine methyltransferase 6 (PRMT6) in vitro and in vivo.

  20. these data demonstrate that PRMT6 overexpression is associated with regulation of motility and invasion through up-regulation of TSP-1 and down-regulation of MMPs in human cancer cells.

Zebrafish Protein Arginine Methyltransferase 6 (PRMT6) interaction partners

  1. these results suggest that maternal Prmt6 is essential to early zebrafish development by directly repressing gadd45alphaa.

Mouse (Murine) Protein Arginine Methyltransferase 6 (PRMT6) interaction partners

  1. Loss of PPARalpha from the intestine promotes colon carcinogenesis by increasing DNMT1/PRMT6-mediated DNA methylation.

  2. It was confirmed that PRMT6 was involved in the process of adipocyte differentiation. In addition, PRMT6 interacted with, but did not methylate, PPARgamma. PRMT6 bound to the PPARresponsive regulatory element of the adipocyte Protein 2 (aP2) promoter in conjunction with PPARgamma and generated the repressive epigenetic mark arginine 2 on histone H3 asymmetric dimethylation, which suppressed aP2 gene expression.

  3. Six crystal structures of PRMT6 from Mus musculus, solved and refined at 1.34 A for the highest resolution structure are described.

  4. Prmt6 is important for embryonic stem cell pluripotency and self-renewal.

  5. The findings define a new regulator of p53 transcriptional regulation and define a role for PRMT6 and arginine methylation in cellular senescence.

Protein Arginine Methyltransferase 6 (PRMT6) 抗原简介

蛋白简介

The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity.

Gene names and symbols associated with PRMT6

  • Arginine methyltransferase 6 (Art6) 抗体
  • protein arginine methyltransferase 6 (PRMT6) 抗体
  • protein arginine methyltransferase 6 S homeolog (prmt6.S) 抗体
  • arginine N-methyltransferase, type I (PRMT6) 抗体
  • protein arginine methyltransferase 6 (prmt6) 抗体
  • protein arginine methyltransferase 6 (Prmt6) 抗体
  • protein arginine N-methyltransferase 6 (Prmt6) 抗体
  • ARABIDOPSIS THALIANA PROTEIN ARGININE METHYLTRANSFERASE 6 抗体
  • ATPRMT6 抗体
  • AW124876 抗体
  • BB233495 抗体
  • CG9927 抗体
  • DART6 抗体
  • DKFZp459B1431 抗体
  • Dmel\\CG9927 抗体
  • hrmt1l6 抗体
  • hrmt6 抗体
  • im:6908706 抗体
  • PRMT6 抗体
  • protein arginine methyltransferase 6 抗体

Protein level used designations for PRMT6

arginine methyltransferase 6 , CG9927-PA , Art6-PA , protein arginine methyltransferase 6 , HMT1 hnRNP methyltransferase-like 6 , Histone-arginine N-methyltransferase PRMT6 , protein arginine N-methyltransferase 6 , arginine N-methyltransferase, type I , heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6 , histone-arginine N-methyltransferase PRMT6

GENE ID SPECIES
41699 Drosophila melanogaster
457073 Pan troglodytes
447344 Xenopus laevis
694284 Macaca mulatta
821541 Arabidopsis thaliana
5067888 Leishmania infantum JPCM5
100145123 Xenopus (Silurana) tropicalis
100172901 Pongo abelii
55170 Homo sapiens
295384 Rattus norvegicus
490133 Canis lupus familiaris
540228 Bos taurus
100156688 Sus scrofa
448867 Danio rerio
99890 Mus musculus
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