PRMT6 抗体 (AA 301-375)
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- 抗原 See all PRMT6 抗体
- PRMT6 (Protein Arginine Methyltransferase 6 (PRMT6))
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抗原表位
- AA 301-375
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PRMT6 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Dog,Cow,Pig,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human PRMT6
- 亚型
- IgG
- Top Product
- Discover our top product PRMT6 Primary Antibody
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anti-Protein Arginine Methyltransferase 6 (PRMT6) (AA 1-316) antibody
PRMT6 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3C3 unconjugated
anti-Protein Arginine Methyltransferase 6 (PRMT6) (AA 19-48) antibodyPRMT6 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 6 (PRMT6) (AA 119-375) antibodyPRMT6 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 6 (PRMT6) (AA 1-316) antibodyPRMT6 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 6 (PRMT6) (AA 1-316) antibodyPRMT6 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 6 (PRMT6) antibodyPRMT6 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 6 (PRMT6) (N-Term) antibodyPRMT6 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 6 (PRMT6) (Internal Region) antibodyVerified PRMT6 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 6 (PRMT6) (C-Term) antibodyPRMT6 适用: 人, 大鼠, 犬, 马, Cow, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 6 (PRMT6) (AA 275-324) antibodyPRMT6 适用: 人, 犬, 猴 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- PRMT6 (Protein Arginine Methyltransferase 6 (PRMT6))
- 别名
- Prmt6 (PRMT6 产品)
- 别名
- CG9927 antibody, DART6 antibody, Dmel\\CG9927 antibody, PRMT6 antibody, HRMT1L6 antibody, ARABIDOPSIS THALIANA PROTEIN ARGININE METHYLTRANSFERASE 6 antibody, ATPRMT6 antibody, protein arginine methyltransferase 6 antibody, DKFZp459B1431 antibody, Hrmt1l6 antibody, hrmt1l6 antibody, hrmt6 antibody, im:6908706 antibody, AW124876 antibody, BB233495 antibody, Arginine methyltransferase 6 antibody, protein arginine methyltransferase 6 antibody, protein arginine methyltransferase 6 S homeolog antibody, arginine N-methyltransferase, type I antibody, protein arginine N-methyltransferase 6 antibody, Art6 antibody, PRMT6 antibody, prmt6.S antibody, prmt6 antibody, Prmt6 antibody
- 背景
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Synonyms: HRMT1L6, Protein arginine N-methyltransferase 6, Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6, Histone-arginine N-methyltransferase PRMT6, PRMT6
Background: Arginine methyltransferase that can catalyze the formation of both omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA), with a strong preference for the formation of aDMA. Preferentially methylates arginyl residues present in a glycine and arginine-rich domain and displays preference for monomethylated substrates. Specifically mediates the asymmetric dimethylation of histone H3 'Arg-2' to form H3R2me2a. H3R2me2a represents a specific tag for epigenetic transcriptional repression and is mutually exclusive with methylation on histone H3 'Lys-4' (H3K4me2 and H3K4me3). Acts as a transcriptional repressor of various genes such as HOXA2, THBS1 and TP53. Repression of TP53 blocks cellular senescence (By similarity). Also methylates histone H2A and H4 'Arg-3' (H2AR3me and H4R3me, respectively). Acts as a regulator of DNA base excision during DNA repair by mediating the methylation of DNA polymerase beta (POLB), leading to the stimulation of its polymerase activity by enhancing DNA binding and processivity. Methylates HMGA1. Regulates alternative splicing events. Acts as a transcriptional coactivator of a number of steroid hormone receptors including ESR1, ESR2, PGR and NR3C1. Promotes fasting-induced transcriptional activation of the gluconeogenic program through methylation of the CRTC2 transcription coactivator. May play a role in innate immunity against HIV-1 in case of infection by methylating and impairing the function of various HIV-1 proteins such as Tat, Rev and Nucleocapsid protein p7 (NC).
- 基因ID
- 55170
- UniProt
- Q96LA8
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