anti-Potassium Channel, Subfamily K, Member 5 (KCNK5) 抗体

KCNK5 encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. 再加上,我们可以发和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
KCNK5 8645 O95279
KCNK5 16529  
KCNK5 364241  
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产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB WB Suggested Anti-KCNK5 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  HepG2 cell lysate 100 μL Log in to see 2至3个工作日
Cow 非结合性 WB WB Suggested Anti-Kcnk5 Antibody   Titration: 1.0 ug/ml   Positive Control: Mouse Liver 100 μL Log in to see 2至3个工作日
Bat 非结合性 IF, IHC, IHC (p), WB Human Placenta (formalin-fixed, paraffin-embedded) stained with KCNK5 antibody ABIN214786 at 2.5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-KCNK5 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other f ... 50 μg Log in to see 11至14个工作日
Cow 非结合性 WB 50 μg Log in to see 7至9个工作日
非结合性 ELISA, WB   200 μL Log in to see 16 Days
非结合性 ELISA, WB 50 μg Log in to see 2至3个工作日
非结合性 WB KCNK5 antibody used at 0.5 ug/ml to detect target protein. 50 μg Log in to see 2至3个工作日
非结合性 IHC, IHC (p) Immunohistochemistry: KCNK5 Antibody [NBP2-32432] - Immunohistochemical staining of human kidney shows positivity in a subset of renal tubules. Immunohistochemistry: KCNK5 Antibody [NBP2-32432] - liver 0.1 mL Log in to see 10至13个工作日
小鼠 非结合性 ELISA Detection limit for recombinant GST tagged KCNK5 is 1 ng/ml as a capture antibody. 100 μg Log in to see 11至12个工作日
非结合性 IHC, WB   100 μL Log in to see 7至8个工作日


Human Potassium Channel, Subfamily K, Member 5 (KCNK5) interaction partners

  1. As a novel finding, our study suggests a role for KCNK5 in the regulation of platelet size and maturity. Furthermore, our findings confirm an association between the SH2B3 (显示 SH2B3 抗体)-locus and platelet count.

  2. In human aldosterone-producing adrenocortical cancer cell lines, roxithromycin inhibited KCNJ5MUT-induced induction of CYP11B2 (显示 CYP11B2 抗体) (encoding aldosterone synthase (显示 CYP11B2 抗体)) expression and aldosterone production.

  3. HLA-DQB1 (显示 HLA-DQB1 抗体)*06:02 does not seem to be associated with hypoxic ventilatory response or hypercapnic ventilatory response; however there are point wise, uncorrected significant associations between two TASK2/KCNK5 variants (rs2815118 and rs150380866) and hypercapnic ventilatory response

  4. These results therefore provide further structural and functional insights into the possible pathophysiological effects of this missense variant in TASK-2.

  5. Results show that up-regulated KCNK5 in activated human T cells does not play a volume regulatory role, due to decreased Cl- permeability suggesting that the KCNK5 upregulation might play a role in hyperpolarization of the cell membrane leading to increased Ca2 (显示 CA2 抗体)+ influx and proliferation of T cells.

  6. Potassium channel (显示 KCNAB2 抗体) TASK2 drives human NK-cell proliferation and cytolytic function.

  7. Mutant genes (CELA1 (显示 CELA1 抗体), HSPG2 (显示 HSPG2 抗体), and KCNK5) in Balkan endemic nephropathy patients encode proteins involved in basement membrane/extracellular matrix and vascular tone, tightly connected to process of angiogenesis.

  8. The TASK-2 channel lower expression represents a hallmark of aldosterone-producing adenoma causing aldosteronism and is associated with a higher expression of hsa (显示 CD24 抗体)-miR (显示 MLXIP 抗体)-23 and hsa (显示 CD24 抗体)-miR (显示 MLXIP 抗体)-34.

  9. Potassium channels, in particular K2P channels, are expressed and functional in the apical membrane of airway epithelial cells

  10. Disease activity in rheumatoid arthritis patients correlates strongly with K(2P)5.1 expression levels in CD4 (显示 CD4 抗体)+ T lymphocytes in the peripheral blood

Mouse (Murine) Potassium Channel, Subfamily K, Member 5 (KCNK5) interaction partners

  1. KCNK5 channels are indispensable for the maintenance of hearing. KCNK5 is mainly found in outer sulcus Claudius', Boettcher's and root cells.

  2. The data identify GPR4 (显示 GPR4 抗体) and TASK-2 as distinct, parallel, and essential central mediators of respiratory chemosensitivity.

  3. TASK-2 is upregulated under hypoxia in a HIF-1alpha (显示 HIF1A 抗体)-dependent manner in B cells.

  4. The strong physiological impairment of KCNK5 in Ehrlich cells after long-term hypotonic stimulation is predominantly due to down-regulation of the KCNK5 protein synthesis.

  5. data are compatible with the concept that TASK-2 channels are modulated by Gbetagamma subunits of heterotrimeric G protein; propose that this modulation is a novel way in which TASK-2 can be tuned to its physiological functions

  6. alkaline-activated TASK-2 channels contribute to pH sensitivity in retrotrapezoid nucleus neurons

  7. Kv1.3 (显示 KCNA3 抗体)/TASK2 channels appear to be mainly responsible for regulatory volume decrease in murine T-lymphocytes.

  8. a cycle of protonation/deprotonation of pH(o)-sensing arginine 224 side chain gates the TASK-2 channel by electrostatically tuning the conformational stability of its selectivity filter.

  9. The authors report for the first time the expression of TASK-2 in B cells and surmise that the upregulation of TASK-2 by B cell receptor ligation is associated with the apoptosis of immature B cells.

  10. intracellular pH, together with pH(o), is a critical determinant of TASK-2 activity and therefore of its physiological function

KCNK5 抗原简介


This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The message for this gene is mainly expressed in the cortical distal tubules and collecting ducts of the kidney. The protein is highly sensitive to external pH and this, in combination with its expression pattern, suggests it may play an important role in renal potassium transport.

Gene names and symbols associated with KCNK5

  • potassium channel, subfamily K, member 5b (kcnk5b) 抗体
  • potassium two pore domain channel subfamily K member 5 (KCNK5) 抗体
  • potassium channel, two pore domain subfamily K, member 5 S homeolog (kcnk5.S) 抗体
  • potassium channel, subfamily K, member 5 (Kcnk5) 抗体
  • potassium two pore domain channel subfamily K member 5 (Kcnk5) 抗体
  • K2p5.1 抗体
  • kcnk5 抗体
  • TASK-2 抗体
  • TASK2 抗体
  • zgc:63921 抗体

Protein level used designations for KCNK5

potassium channel, subfamily K, member 5 , potassium channel subfamily K member 5-like , K2P5.1 potassium channel , TWIK-related acid-sensitive K(+) channel 2 , TWIK-related acid-sensitive K+ channel 2 , acid-sensitive potassium channel protein TASK-2 , potassium channel subfamily K member 5 , potassium channel, subfamily K, member 1 (TASK-2) , potassium inwardly-rectifying channel, subfamily K, member 5

393606 Danio rerio
421424 Gallus gallus
496362 Xenopus laevis
100436248 Pongo abelii
8645 Homo sapiens
481780 Canis lupus familiaris
782166 Bos taurus
100009446 Oryctolagus cuniculus
16529 Mus musculus
364241 Rattus norvegicus
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