Oxysterol Binding Protein-Like 5 蛋白 (OSBPL5)

OSBPL5 encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors that play a key role in the maintenance of cholesterol balance in the body. 再加上,我们可以发Oxysterol Binding Protein-Like 5 抗体 (24)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
大鼠 OSBPL5 OSBPL5 361686  
OSBPL5 114879 Q9H0X9
OSBPL5 79196 Q9ER64
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产品编号 Origin 资源 标记 图像 规格 供应商 交付 价格 详细
Insect Cells rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 60至65个工作日
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Insect Cells 小鼠 rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 60至65个工作日
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HEK-293 Cells Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
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小麦胚 GST tag 10 μg Log in to see 11至12个工作日
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OSBPL5 蛋白 by Origin and Source

Origin 在表达 标记
Human , ,
, ,
Mouse (Murine)

更多Oxysterol Binding Protein-Like 5 (OSBPL5)互动伙伴

Cow (Bovine) Oxysterol Binding Protein-Like 5 (OSBPL5) interaction partners

  1. imprinting status of four cattle genes (Tssc4 (显示 TSSC4 蛋白),Nap1l4 (显示 NAP1L4 蛋白), Phlda2 (显示 PHLDA2 蛋白) and Osbpl5) in seven types of tissues, were assessed in cattle.

Human Oxysterol Binding Protein-Like 5 (OSBPL5) interaction partners

  1. ORP5/8 are endoplasmic reticulum (ER) membrane proteins implicated in lipid trafficking that localize to ER-plasma membrane (PM) contacts and maintain membrane homeostasis. Here the authors show that PtdIns(4,5)P 2 plays a critical role in the targeting and function of ORP5/8 at the PM.

  2. mammalian ORP5 and ORP8 (显示 OSBPL8 蛋白) proteins localize to ER-mitochondrial MCS (显示 SMCP 蛋白), in addition to ER-PM contact sites.

  3. Results show that OSBPL5 and CALU (显示 CALU 蛋白) were expressed at higher levels in the lung tissues of metastasis-positive cases than that in the metastasis-negative cases suggesting they can promote invasiveness of lung cancer cells.

  4. ORP5 and ORP8 (显示 OSBPL8 蛋白) could mediate PI4P/phosphatidylserine (PS) countertransport between the endoplasmic reticulum (ER) and the plasma membrane (PM), thus delivering PI4P to the ER-localized PI4P phosphatase Sac1 (显示 SACM1L 蛋白) for degradation and PS from the ER to the PM.

  5. ORP5 may cooperate with NPC1 (显示 NPC1 蛋白) to mediate the exit of cholesterol from endosomes/lysosomes.

  6. OBPH1/Obph1 gene is imprinted, with preferential expression from the maternal allele in human and mouse.

  7. Telomeric NAP1L4 (显示 NAP1L4 蛋白) and OSBPL5 of the KCNQ1 (显示 KCNQ1 蛋白) cluster, and the DECORIN (显示 DCN 蛋白) gene are not imprinted in human trophoblast stem cells.

  8. OSBPL5 is relatd to invasion and poor prognosis in pancreatic cancer.

Mouse (Murine) Oxysterol Binding Protein-Like 5 (OSBPL5) interaction partners

  1. OBPH1/Obph1 gene is imprinted, with preferential expression from the maternal allele in human and mouse.

  2. OSBP (显示 OSBP 蛋白) regulates hepatic TG metabolism and suggest the involvement of OSBP (显示 OSBP 蛋白) in the insulin (显示 INS 蛋白) signaling pathways that control hepatic lipogenesis.

蛋白简介Oxysterol Binding Protein-Like 5 (OSBPL5)

蛋白简介

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors that play a key role in the maintenance of cholesterol balance in the body. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. This gene has been shown to be imprinted, with preferential expression from the maternal allele only in placenta. Transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with OSBPL5

  • oxysterol binding protein-like 5 (Osbpl5)
  • oxysterol binding protein like 5 (OSBPL5)
  • oxysterol binding protein like 5 (osbpl5)
  • 1110006M06Rik 蛋白
  • AI462538 蛋白
  • MGC109308 蛋白
  • Obph1 蛋白
  • ORP5 蛋白
  • Osbp2 蛋白
  • OSBPL5 蛋白

Protein level used designations for OSBPL5

oxysterol binding protein-like 5 , oxysterol-binding protein-related protein 5-like , ORP-5 , OSBP-related protein 5 , oxysterol-binding protein homolog 1 , oxysterol-binding protein homologue 1 , oxysterol-binding protein-related protein 5 , oxysterol binding protein 2 , oxysterol binding protein homolog 1 , oxysterol-binding protein-like protein 5

GENE ID SPECIES
361686 Rattus norvegicus
483671 Canis lupus familiaris
532690 Bos taurus
770816 Gallus gallus
100431919 Pongo abelii
100466215 Ailuropoda melanoleuca
100515995 Sus scrofa
100539452 Meleagris gallopavo
100564429 Anolis carolinensis
114879 Homo sapiens
79196 Mus musculus
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