anti-Methyl-CpG Binding Domain Protein 1 (MBD1) 抗体

The protein encoded by MBD1 is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). 再加上,我们可以发MBD1 蛋白 (4)MBD1 试剂盒 (3)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
MBD1 4152 Q9UIS9
MBD1 17190 Q9Z2E2
MBD1 291439  
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antibodies-online.cn销售最多的anti-MBD1 抗体

Showing 10 out of 76 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 交付 价格 详细
Cow 非结合性 WB WB Suggested Anti-MBD1 Antibody Titration:  0.2-1 ug/ml  Positive Control:  HepG2 cell lysate 100 μL 2至3个工作日
$289.00
详细
非结合性 WB WB Suggested Anti-MBD1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  HepG2 cell lysate 100 μL 2至3个工作日
$289.00
详细
Cow 非结合性 IHC, WB WB Suggested Anti-MBD1 Antibody   Titration: 1.0 ug/ml   Positive Control: 293T Whole Cell MBD1 is strongly supported by BioGPS gene expression data to be expressed in Human HEK293T cells Rabbit Anti-MBD1 antibody  Formalin Fixed Paraffin Embedded Tissue: Human Testis Primary antibody Concentration: 1:100 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20x Exposure Time: 0.5-2.0sec 100 μL 2至3个工作日
$289.00
详细
非结合性 WB 100 μg 2至3个工作日
$245.00
详细
非结合性 ChIP, ELISA, WB 25 μg 2至3个工作日
$245.00
详细
Bat 非结合性 IHC, IHC (p), WB Human Kidney (formalin-fixed, paraffin-embedded) stained with MBD1 antibody ABIN214123 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-MBD1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. This image was taken for the unconjugated form of this product. Other for ... 100 μL 11至14个工作日
$727.83
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小鼠 非结合性 WB 100 μg 11至14个工作日
$507.83
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Bat 非结合性 WB 100 μL 11至14个工作日
$493.17
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非结合性 WB 100 μg 11至14个工作日
$507.83
详细
非结合性 WB 100 μL 11至14个工作日
$551.83
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引用最多的anti-MBD1 抗体

  1. Human Monoclonal MBD1 Primary Antibody for ChIP, IP - ABIN252496 : Reese, Bachman, Baylin, Rountree: The methyl-CpG binding protein MBD1 interacts with the p150 subunit of chromatin assembly factor 1. in Molecular and cellular biology 2003 (PubMed)
    Show all 8 Pubmed References

  2. Human Polyclonal MBD1 Primary Antibody for IF, WB - ABIN517757 : Staples, Myers, Beveridge, Patil, Lee, Swanton, Howell, Boulton, Collis: The centriolar satellite protein Cep131 is important for genome stability. in Journal of cell science 2012 (PubMed)
    Show all 2 Pubmed References

  3. Cow (Bovine) Polyclonal MBD1 Primary Antibody for WB - ABIN2779420 : Villa, Morey, Raker, Buschbeck, Gutierrez, De Santis, Corsaro, Varas, Bossi, Minucci, Pelicci, Di Croce: The methyl-CpG binding protein MBD1 is required for PML-RARalpha function. in Proceedings of the National Academy of Sciences of the United States of America 2006 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal MBD1 Primary Antibody for ChIP, ELISA - ABIN542436 : Xiong, Dowdy, Eberhardt, Podratz, Jiang: hMLH1 promoter methylation and silencing in primary endometrial cancers are associated with specific alterations in MBDs occupancy and histone modifications. in Gynecologic oncology 2006 (PubMed)

更多抗MBD1的相互作用对抗体

Human Methyl-CpG Binding Domain Protein 1 (MBD1) interaction partners

  1. ZEB1 silenced SIRT3 expression via interaction with MBD1 to promote aerobic glycolysis in pancreatic cancer.

  2. MBD1 may be a tumor suppressor gene in advanced colorectal cancer (CRC)and affect the development and metastasis of CRC by regulating 8 tumor suppressor genes through binding with SP1.

  3. Our findings imply that reduced stability and enhanced dynamics of MBD1 or MBD6 is the origin of ATP7B dysfunction in Wilson disease patients with the G85V or G591D mutation.

  4. MBD1 regulates localization and activity of Tet1 in a CXXC3 domain-dependent manner.

  5. the binding of MBD1 to nucleosomes demonstrates sequence preferences depending on the position of the methyl groups on the nucleosome.

  6. c-myc plays a key role in MBD1 mediated epigenetic silencing of KEAP1.

  7. Molecular dynamic simulation reveals mechanism of the recognition of dimethylated CpG sites by MBD1 protein.

  8. MBD1 targets short interspersed nuclear elements, but does not exclude RNA Polymerase III.

  9. This study investigates the genetic association between methyl-CpG-binding domain (MBD) gene polymorphisms and schizophrenia.

  10. We demonstrated the importance of Aire's interaction with the ATF7ip-MBD1 protein complex in maintaining central tolerance

  11. an important function of MBD1 in DNA repair and mediation of chemoradioresistance of cancer cells

  12. higher MBD1 expression correlated with lymph node metastasis and poor survival in pancreatic cancer; gain- and loss-of-function studies in vitro validated MBD1 as a potent oncogene promoting pancreatic cancer cell invasion and epithelial-mesenchymal transition

  13. MBD1-containing chromatin associated factor 2, epithelial malignancy-related vimentin and exocytosis-related annexin A2 were changed upon exposure to airborne nanoparticle PM(0.056).

  14. This review tries to match MeCP2 structural domains, or their lack, and specific chromatin features needed for proper recruitment of MeCP2 to its functions as either activator or repressor. We specifically focused on MeCP2's role in Rett syndrome

  15. lack of binding to mCpG and interaction with NuRD/Mi2 components HDAC1 and MTA2

  16. investigation of role of specific mutations in autism

  17. Results show that methyl-CpG binding domain protein 1 (MBD1) is expressed in tumor cells, but methyl-CpG binding domain protein 2 (MBD2) and methyl CpG binding protein 2 (MeCP2) are not.

  18. MCAF interacts with the transcriptional repression domain of MBD1

  19. Suv39h1 enhanced MBD1-mediated transcriptional repression via MBD, not the C-terminal transcriptional repression domain of MBD1. MBD1 links to histone deacetylases through Suv39h1, causing methylation and deacetylation of histones for gene inactivation

  20. Additional evidence of variable expression in the Rett disorder phenotype is presented by a small mixed gender group of children with autistic disorder.

Mouse (Murine) Methyl-CpG Binding Domain Protein 1 (MBD1) interaction partners

  1. Knock-out MBD1 mice displayed reduced responses in the dorsal root ganglia to acute pain and neuropathic pain.

  2. MBD1 regulates localization and activity of Tet1 in a CXXC3 domain-dependent manner.

  3. MBD1 has a role in neural stem cell maintenance and epigenetic regulation.

  4. MBD1 targets short interspersed nuclear elements, but does not exclude RNA Polymerase III.

  5. We demonstrated the importance of Aire's interaction with the ATF7ip-MBD1 protein complex in maintaining central tolerance

  6. H19 lncRNA controls gene expression of the Imprinted Gene Network by recruiting MBD1.

  7. regulatory loop formed by MBD1 and miR-195 is an important component of the epigenetic network that controls aNSC fate

  8. MBD1, miR-184, and Numbl form a regulatory network that helps control the balance between proliferation and differentiation of adult neural stem/progenitor cells.

  9. Results indicate that MBD1 can interpret the CpG dinucleotide as a repressive signal in vivo regardless of its methylation status.

  10. These data show, for the first time, the involvement of methyl-CpG binding domain proteins in the regulation of the MAGE-A genes.

  11. Mbd1(-/-) mice exhibit several core deficits associated with autism, including reduced social interaction, learning deficits, anxiety, defective sensory motor gating, depression and abnormal brain serotonin activity.

  12. Mbd1 and DNA methylation-mediated epigenetic mechanism regulated the expression of stem cell mitogen Fgf-2 in adult neural stem/progenitor cells.

MBD1 抗原简介

蛋白简介

The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains multiple domains: MBD at the N-terminus that functions both in binding to methylated DNA and in protein interactions\; several CXXC-type zinc finger domains that mediate binding to non-methylated CpG dinucleotides\; transcriptional repression domain (TRD) at the C-terminus that is involved in transcription repression and in protein interactions. Numerous alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Gene names and symbols associated with MBD1

  • methyl-CpG binding domain protein 1 (MBD1) 抗体
  • methyl-CpG binding domain protein 1 (Mbd1) 抗体
  • CCDC11 抗体
  • Cxxc3 抗体
  • PCM1 抗体
  • RFT 抗体

Protein level used designations for MBD1

CXXC-type zinc finger protein 3 , methyl-CpG binding domain protein 1 isoform PCM1 , methyl-CpG-binding domain protein 1 , protein containing methyl-CpG-binding domain 1 , the regulator of fibroblast growth factor 2 (FGF-2) transcription , methyl-CpG-binding protein MBD1 , coiled-coil domain containing 11

GENE ID SPECIES
4152 Homo sapiens
17190 Mus musculus
291439 Rattus norvegicus
480218 Canis lupus familiaris
540558 Bos taurus
100724675 Cavia porcellus
101116619 Ovis aries musimon
100340239 Oryctolagus cuniculus
100053867 Equus caballus
100156150 Sus scrofa
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