MBD1 抗体
(Methyl-CpG Binding Domain Protein 1 (MBD1))
The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains multiple domains: MBD at the N-terminus that functions both in binding to methylated DNA and in protein interactions\; several CXXC-type zinc finger domains that mediate binding to non-methylated CpG dinucleotides\; transcriptional repression domain (TRD) at the C-terminus that is involved in transcription repression and in protein interactions. Numerous alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Feb 2011].
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MBD1 抗体 by 适用
Find MBD1 抗体 for a variety of species such as anti-Human MBD1, anti-Rat MBD1, anti-Dog MBD1. The species listed below are among those available. Click on a link to go to the corresponding products.
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Find MBD1 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
MBD1 抗体 by 抗原表位
Find MBD1 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.
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Cat. No.
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Quantity
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Cat. No.
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Quantity
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Datasheet
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Bat, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
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Cat. No.
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Cat. No.
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Quantity
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Cat. No.
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Quantity
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Datasheet
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Reactivity
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Cat. No.
ABIN208588
Quantity
0.1 mg
Datasheet
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Reactivity
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Datasheet
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Latest Publications for our MBD1 抗体
: "SUMO-2 Orchestrates Chromatin Modifiers in Response to DNA Damage." in: Cell reports, (2015) (PubMed).: "SINE transcription by RNA polymerase III is suppressed by histone methylation but not by DNA methylation." in: Nature communications, Vol. 6, pp. 6569, (2015) (PubMed).
: "Ccdc13 is a novel human centriolar satellite protein required for ciliogenesis and genome stability." in: Journal of cell science, Vol. 127, Issue Pt 13, pp. 2910-9, (2014) (PubMed).
: "The transcriptional regulator Aire coopts the repressive ATF7ip-MBD1 complex for the induction of immunotolerance." in: Nature immunology, Vol. 15, Issue 3, pp. 258-65, (2014) (PubMed).
: "The centriolar satellite protein Cep131 is important for genome stability." in: Journal of cell science, Vol. 125, Issue Pt 20, pp. 4770-9, (2012) (PubMed).
: "Epigenetic silence of ankyrin-repeat-containing, SH3-domain-containing, and proline-rich-region- containing protein 1 (ASPP1) and ASPP2 genes promotes tumor growth in hepatitis B virus-positive ..." in: Hepatology (Baltimore, Md.), Vol. 51, Issue 1, pp. 142-53, (2009) (PubMed).
: "Methods in cancer epigenetics and epidemiology." in: Methods in molecular biology (Clifton, N.J.), Vol. 471, pp. 273-88, (2008) (PubMed).
: "Dynamic changes in the localization of five members of the methyl binding domain (MBD) gene family during murine and bovine preimplantation embryo development." in: Molecular reproduction and development, Vol. 75, Issue 1, pp. 48-59, (2007) (PubMed).
: "Role of the polycomb repressive complex 2 in acute promyelocytic leukemia." in: Cancer cell, Vol. 11, Issue 6, pp. 513-25, (2007) (PubMed).
: "hMLH1 promoter methylation and silencing in primary endometrial cancers are associated with specific alterations in MBDs occupancy and histone modifications." in: Gynecologic oncology, Vol. 103, Issue 1, pp. 321-8, (2006) (PubMed).
Aliases for MBD1 抗体
methyl-CpG binding domain protein 1 (MBD1) 抗体methyl-CpG binding domain protein 1 (Mbd1) 抗体
CCDC11 抗体
CXXC3 抗体
Cxxc3 抗体
PCM1 抗体
RFT 抗体
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