anti-MBD1 抗体

蛋白简介

The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains multiple domains: MBD at the N-terminus that functions both in binding to methylated DNA and in protein interactions\; several CXXC-type zinc finger domains that mediate binding to non-methylated CpG dinucleotides\; transcriptional repression domain (TRD) at the C-terminus that is involved in transcription repression and in protein interactions. Numerous alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Gene names and symbols associated with MBD1

• methyl-CpG binding domain protein 1 (MBD1) 抗体
• methyl-CpG binding domain protein 1 (Mbd1) 抗体

• CCDC11 抗体
• Cxxc3 抗体
• PCM1 抗体
• RFT 抗体

Protein level used designations for MBD1

CXXC-type zinc finger protein 3 , methyl-CpG binding domain protein 1 isoform PCM1 , methyl-CpG-binding domain protein 1 , protein containing methyl-CpG-binding domain 1 , the regulator of fibroblast growth factor 2 (FGF-2) transcription , methyl-CpG-binding protein MBD1 , coiled-coil domain containing 11