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MBD2 抗体

(Methyl-CpG Binding Domain Protein 2 (MBD2))
DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. The protein encoded by this gene may function as a mediator of the biological consequences of the methylation signal. It is also reported that the this protein functions as a demethylase to activate transcription, as DNA methylation causes gene silencing. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011].
MBD2 抗体  (Internal Region) MBD2 抗体  (Internal Region) MBD2 抗体 (Internal Region) (ABIN334432)

Verified MBD2 适用: 人 IHC, ELISA, WB 宿主: 山羊 Polyclonal unconjugated

MBD2 抗体  (N-Term) MBD2 抗体  (N-Term) MBD2 抗体 (N-Term) (ABIN2779675)

MBD2 适用: 人, 小鼠, 大鼠 IHC, WB 宿主: 兔 Polyclonal unconjugated

MBD2 抗体  (Middle Region) MBD2 抗体  (Middle Region) MBD2 抗体 (Middle Region) (ABIN2778640)

MBD2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 IHC, WB 宿主: 兔 Polyclonal unconjugated

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MBD2 抗体 by 适用

Find MBD2 抗体 for a variety of species such as anti-Human MBD2, anti-Mouse MBD2, anti-Rat MBD2. The species listed below are among those available. Click on a link to go to the corresponding products.

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Popular MBD2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application IHC, WB
Validations
  • (3)
Cat. No. ABIN6569193
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN3043613
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB
Validations
  • (2)
Cat. No. ABIN5531571
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN2856140
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, ICC, IF, WB
Validations
  • (1)
Cat. No. ABIN6263148
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF, WB
Validations
  • (3)
Cat. No. ABIN1881531
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application IP, IHC, ELISA, WB
Validations
  • (1)
Cat. No. ABIN347698
Quantity 200 μL
Datasheet Datasheet
Reactivity Bat, Chicken, Cow, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN202197
Quantity 100 μL
Datasheet Datasheet
Reactivity Bat, Human, Monkey, Mouse, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6742279
Quantity 100 μL
Datasheet Datasheet
Reactivity Dog, Guinea Pig, Human, Mouse, Pig
Application IF, IHC, IHC (p), IP, WB
Validations
  • (1)
Cat. No. ABIN2625251
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application EIA, IHC (fro), IP, WB
Validations
  • (1)
Cat. No. ABIN1108166
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human, Rat
Application ELISA, WB
Validations
Cat. No. ABIN7116241
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ICC, IHC, IP, WB
Validations
Cat. No. ABIN6997044
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB
Validations
Cat. No. ABIN629604
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
Cat. No. ABIN7134754
Quantity 150 μL
Datasheet Datasheet

Latest Publications for our MBD2 抗体

Zhao, Sentürk, Song, Grummt: "lncRNA PAPAS tethered to the rDNA enhancer recruits hypophosphorylated CHD4/NuRD to repress rRNA synthesis at elevated temperatures." in: Genes & development, Vol. 32, Issue 11-12, pp. 836-848, (2018) (PubMed).

Kim, Kwak, Weitz: "Specificity in circadian clock feedback from targeted reconstitution of the NuRD corepressor." in: Molecular cell, Vol. 56, Issue 6, pp. 738-48, (2014) (PubMed).

Bartels, Spruijt, Brinkman, Jansen, Vermeulen, Stunnenberg: "A SILAC-based screen for Methyl-CpG binding proteins identifies RBP-J as a DNA methylation and sequence-specific binding protein." in: PLoS ONE, Vol. 6, Issue 10, pp. e25884, (2012) (PubMed).

Spruijt, Bartels, Brinkman, Tjeertes, Poser, Stunnenberg, Vermeulen: "CDK2AP1/DOC-1 is a bona fide subunit of the Mi-2/NuRD complex." in: Molecular bioSystems, Vol. 6, Issue 9, pp. 1700-6, (2010) (PubMed).

Liu, Wu, Chen, Ter-Minassian, Asomaning, Zhai, Wang, Su, Heist, Kulke, Lin, Liu, Christiani: "A Large-scale genetic association study of esophageal adenocarcinoma risk." in: Carcinogenesis, Vol. 31, Issue 7, pp. 1259-63, (2010) (PubMed).

Guey, García-Closas, Murta-Nascimento, Lloreta, Palencia, Kogevinas, Rothman, Vellalta, Calle, Marenne, Tardón, Carrato, García-Closas, Serra, Silverman, Chanock, Real, Malats: "Genetic susceptibility to distinct bladder cancer subphenotypes." in: European urology, Vol. 57, Issue 2, pp. 283-92, (2010) (PubMed).

Hosgood, Menashe, He, Chanock, Lan: "PTEN identified as important risk factor of chronic obstructive pulmonary disease." in: Respiratory medicine, Vol. 103, Issue 12, pp. 1866-70, (2009) (PubMed).

Zhao, Wu, Bu, Lu, Liang, Cao, Tong, Lu, Wu, Guo et al.: "Epigenetic silence of ankyrin-repeat-containing, SH3-domain-containing, and proline-rich-region- containing protein 1 (ASPP1) and ASPP2 genes promotes tumor growth in hepatitis B virus-positive ..." in: Hepatology (Baltimore, Md.), Vol. 51, Issue 1, pp. 142-53, (2009) (PubMed).

Tan, Nakielny: "Control of the DNA methylation system component MBD2 by protein arginine methylation." in: Molecular and cellular biology, Vol. 26, Issue 19, pp. 7224-35, (2006) (PubMed).

Le Guezennec, Vermeulen, Brinkman, Hoeijmakers, Cohen, Lasonder, Stunnenberg: "MBD2/NuRD and MBD3/NuRD, two distinct complexes with different biochemical and functional properties." in: Molecular and cellular biology, Vol. 26, Issue 3, pp. 843-51, (2006) (PubMed).

Aliases for MBD2 抗体

methyl-CpG binding domain protein 2 (MBD2) 抗体
methyl-CpG binding domain protein 2 (Mbd2) 抗体
methyl-CpG binding domain protein 2 (mbd2) 抗体
methyl-CpG binding domain protein 2 S homeolog (mbd2.S) 抗体
DMTase 抗体
MBD2 抗体
MBD2a 抗体
NY-CO-41 抗体
wu:fa97f06 抗体
zgc:111862 抗体
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