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MBD2 抗体 (Center)

MBD2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2856140
发货至: 中国
  • 抗原 See all MBD2 抗体
    MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))
    抗原表位
    • 10
    • 8
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    适用
    • 49
    • 24
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 46
    • 2
    • 1
    克隆类型
    • 45
    • 4
    多克隆
    标记
    • 27
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MBD2 antibody is un-conjugated
    应用范围
    • 42
    • 22
    • 6
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    交叉反应
    小鼠, 大鼠, 非洲爪蟾
    交叉反应 (详细)
    Mouse (98 %), Rat (98 %), Xenopus laevis (89 %)
    产品特性
    Rabbit polyclonal antibody to MBD2 (methyl-CpG binding domain protein 2)
    MBD2 antibody [N2C3]
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human MBD2. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product MBD2 Primary Antibody
  • 应用备注
    Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*
    说明

    Positive Control: A431 , Jurkat , Raji

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.48 mg/mL
    缓冲液
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))
    别名
    MBD2 (MBD2 产品)
    别名
    MBD2 antibody, DMTase antibody, NY-CO-41 antibody, MBD2a antibody, wu:fa97f06 antibody, zgc:111862 antibody, methyl-CpG binding domain protein 2 antibody, methyl-CpG binding domain protein 2 S homeolog antibody, MBD2 antibody, Mbd2 antibody, mbd2 antibody, mbd2.S antibody
    背景
    DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. The protein encoded by this gene may function as a mediator of the biological consequences of the methylation signal. It is also reported that the this protein functions as a demethylase to activate transcription, as DNA methylation causes gene silencing.

    Cellular Localization: Nucleus
    分子量
    43 kDa
    基因ID
    8932
    途径
    Chromatin Binding
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