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MBD1 抗体 (C-Term)

MBD1 适用: 人, 大鼠, 犬, Cow, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2777532
发货至: 中国
  • 抗原 See all MBD1 抗体
    MBD1 (Methyl-CpG Binding Domain Protein 1 (MBD1))
    抗原表位
    • 15
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term
    适用
    • 42
    • 18
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 大鼠, 犬, Cow, 豚鼠, 马, 兔
    宿主
    • 33
    • 9
    克隆类型
    • 35
    • 7
    多克隆
    标记
    • 24
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MBD1 antibody is un-conjugated
    应用范围
    • 34
    • 14
    • 13
    • 13
    • 5
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    EEDKEENKDD SASKLAPEEE AGGAGTPVIT EIFSLGGTRF RDTAVWLPRS
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Rabbit: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against MBD1. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    Top Product
    Discover our top product MBD1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 629 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    MBD1 (Methyl-CpG Binding Domain Protein 1 (MBD1))
    别名
    MBD1 (MBD1 产品)
    别名
    CXXC3 antibody, PCM1 antibody, RFT antibody, Cxxc3 antibody, CCDC11 antibody, methyl-CpG binding domain protein 1 antibody, MBD1 antibody, Mbd1 antibody
    背景
    The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains multiple domains: MBD at the N-terminus that functions both in binding to methylated DNA and in protein interactions, several CXXC-type zinc finger domains that mediate binding to non-methylated CpG dinucleotides, transcriptional repression domain (TRD) at the C-terminus that is involved in transcription repression and in protein interactions. Numerous alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
    Alias Symbols: CXXC3, PCM1, RFT
    Protein Interaction Partner: SUMO1, HTT, UBC, ECT2, APP, ATXN1L, TENM1, SUMO2, HIST1H3A, PCNA, ATF7IP2, ATF7IP, CHAF1A, SETDB1, PIAS1, STAT1, PRAM1, HDAC3, PIAS2, ZNF512B, Rnf2, CBX4, CBX5, HIPK3, SMAD9, OASL, SMAD5, SMAD3, SMAD7, SMAD1, SUV39H1,
    Protein Size: 629
    分子量
    69 kDa
    基因ID
    4152
    NCBI登录号
    NM_001204138, NP_001191067
    UniProt
    Q9UIS9
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