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- 抗原 See all MBD1 抗体
- MBD1 (Methyl-CpG Binding Domain Protein 1 (MBD1))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MBD1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Chromatin Immunoprecipitation (ChIP)
- 交叉反应 （详细）
- Cross reactivity with other species was not tested.
- 纯化方法
- Anti-MBD1 Antibody was purified by affinity purification.
- 免疫原
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Immunogen: Anti-MBD1 Antibody was produced in rabbits by repeated immunizations with a synthetic peptide containing a sequence from the N-terminus of human MBD1.
Immunogen Type: Peptide
- 亚型
- IgG
- Top Product
- Discover our top product MBD1 Primary Antibody
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anti-Methyl-CpG Binding Domain Protein 1 (MBD1) (AA 415-508) antibody
MBD1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2C7 unconjugated
anti-Methyl-CpG Binding Domain Protein 1 (MBD1) (AA 415-508) antibodyMBD1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4F6 unconjugated
anti-Methyl-CpG Binding Domain Protein 1 (MBD1) (AA 1-605) antibodyMBD1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 1 (MBD1) (C-Term) antibodyMBD1 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 1 (MBD1) (N-Term) antibodyMBD1 适用: 人 ELISA, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 1 (MBD1) (AA 106-355) antibodyMBD1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 1 (MBD1) (AA 376-405), (C-Term) antibodyMBD1 适用: 人 WB 宿主: 兔 Polyclonal RB2371 unconjugated
anti-Methyl-CpG Binding Domain Protein 1 (MBD1) (N-Term) antibodyMBD1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 1 (MBD1) (C-Term) antibodyMBD1 适用: 人, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 小鼠, 猴, Bat, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 1 (MBD1) (C-Term) antibodyMBD1 适用: 人, 大鼠, 犬, Cow, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Application Note: Anti-MBD1 Antibody is suitable for Chromatin Immunoprecipitation, ELISA and Western Blots. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 75 kDa in the appropriate cell lysate or extract.
ChIP Dilution: 1.5 μg per IP
ELISA Dilution: 1:1,000
Western Blot Dilution: 1:500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Buffer: 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
0.05 % (w/v) Sodium Azide and 0.05 % ProClin 300/p>Stabilizer: None
- 储存液
- ProClin, Sodium azide
- 注意事项
- This product contains Sodium azide and ProClin: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 储存条件
- RT,4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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- 抗原
- MBD1 (Methyl-CpG Binding Domain Protein 1 (MBD1))
- 别名
- MBD1 (MBD1 产品)
- 别名
- CXXC3 antibody, PCM1 antibody, RFT antibody, Cxxc3 antibody, CCDC11 antibody, methyl-CpG binding domain protein 1 antibody, MBD1 antibody, Mbd1 antibody
- 背景
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Synonyms: Methyl-CpG-binding domain protein 1, CXXC-type zinc finger protein 3, Methyl-CpG-binding protein MBD1, Protein containing methyl-CpG-binding domain 1, CXXC3, PCM1
Background: MBD1 is a transcriptional repressor that specifically binds to methylated CpG dinucleotides in promoter sequences. MBD1 acts by recruiting a variety of histone deacetylases (HDAC's) and chromatin remodelling factors. MBD1-dependent transcriptional repression is mediated by ATF7IP through the recruitment of factors such as the histone methyltransferase SETDB1. MBD1 probably forms a complex with SETDB1 and ATF7IP which couples DNA methylation to H3K9 trimethylation and represses transcription. Anti-MBD1 Antibody is ideal for research in Epigenetics, Gene Expression and Chromatin Remodeling.
Gene Name: MBD1
- 基因ID
- 4152
- NCBI登录号
- NP_001191065
- UniProt
- Q9UIS9
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