Meprin A, beta (MEP1B) ELISA试剂盒

Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes, and in leukocytes and certain cancer cells. 再加上,我们可以发Meprin B 抗体 (18)Meprin B 蛋白 (10)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
MEP1B 17288 Q61847
MEP1B 25727 P28826
MEP1B 4225 Q16820
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适于 Meprin B 相互作用对的更多 ELISA 试剂盒

Zebrafish Meprin A, beta (MEP1B) interaction partners

Mouse (Murine) Meprin A, beta (MEP1B) interaction partners

  1. Results provide evidence that meprin beta is involved in collagen deposition in vivo in the lung of bleomycin treated mice and it localized in region with immature collagen. This suggests that meprin beta can favor the progression of the fibrotic process enhancing collagen processing and deposition.

  2. This secreted cysteine protease (显示 CTSW ELISA试剂盒) potently converts membrane-bound meprin beta into its active form, impairing meprin beta shedding and its function as a mucus-detaching protease

  3. no significant dentin malformation was observed in Mep1b (-/-) or Mep1a (显示 MEP1A ELISA试剂盒) (-/-) deficient mice.

  4. meprin alpha (显示 MEP1A ELISA试剂盒) and meprin beta join the modulators of Reelin (显示 RELN ELISA试剂盒) signalling as they cleave Reelin (显示 RELN ELISA试剂盒) at a specific site and are upregulated under specific pathological conditions.

  5. These studies provide strong evidence for a pathophysiological link between meprin beta and urinary excretion of cleaved nidogen-1 (显示 NID1 ELISA试剂盒) during cisplatin-induced acute kidney injury.

  6. While meprin A only cleaved protein kinase A (PKA) catalytic subunit beta1, meprin B cleaved all three PKA catalytic isoforms.

  7. Meprin beta is an endogenous zinc-dependent metalloprotease (显示 ADAMTS7 ELISA试剂盒) now shown to cleave the N-terminal region of the MUC2 (显示 MUC2 ELISA试剂盒) mucin (显示 SLC13A2 ELISA试剂盒) at two specific sites.

  8. Suggest role for in meprin-beta-Fra2 (显示 FOSL2 ELISA试剂盒) axis in mediating vascular remodelling in pulmonary hypertension.

  9. meprin alpha (显示 MEP1A ELISA试剂盒) and meprin beta are unique in their ability to process and release both C- and N-propeptides from type I procollagen (显示 COL1A2 ELISA试剂盒) in vitro and in vivo

  10. of the 151 new extracellular substrates identified, it was notable that ADAM10 (显示 ADAM10 ELISA试剂盒) the constitutive alpha-secretase-is activated by meprin beta through cleavage of the propeptide

Human Meprin A, beta (MEP1B) interaction partners

  1. Results provide evidence that meprin beta is involved in collagen deposition in vivo in the lung of bleomycin treated mice and it localized in region with immature collagen. This suggests that meprin beta can favor the progression of the fibrotic process enhancing collagen processing and deposition.

  2. This secreted cysteine protease (显示 CTSB ELISA试剂盒) potently converts membrane-bound meprin beta into its active form, impairing meprin beta shedding and its function as a mucus-detaching protease

  3. For meprin beta a reduction and for BMP-1 (显示 BMP1 ELISA试剂盒) an increase in activity was reported under increasing calcium concentrations.

  4. In this review we report on recent findings that summarize the complex molecular regulation of meprins, particular folding, activation and shedding. Dysregulation of meprin alpha (显示 MEP1A ELISA试剂盒) and meprin beta is often associated with pathological conditions such as neurodegeneration, inflammatory bowel disease and fibrosis

  5. TSPAN8 (显示 TSPAN8 ELISA试剂盒) might be important for the orchestration of meprin beta at the cell surface with impact on certain proteolytic processes

  6. n conclusion, we show that the concept of cleavable linkers specific for meprin beta is feasible, as the peptides are rapidly cleaved by the enzyme while retaining their biological properties

  7. Meprin Beta was found to be activated at the cell surface by matriptase-2 (显示 TMPRSS6 ELISA试剂盒).

  8. promotes inflammation in macrophages via ADAM-10 (显示 ADAM10 ELISA试剂盒) dependent pathway

  9. Overexpression of MEP1B is associated with pancreatic neuroendocrine tumors.

  10. Suggest role for in meprin-beta-Fra2 (显示 FOSL2 ELISA试剂盒) axis in mediating vascular remodelling in pulmonary hypertension.

Meprin B (MEP1B) 抗原简介

Antigen Summary

Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes, and in leukocytes and certain cancer cells. They are involved in the hydrolysis of a variety of peptide and protein substrates, and have been implicated in cancer and intestinal inflammation. Mature meprins are oligomers of evolutionarily related, but separately encoded alpha and/or beta subunits. Homooligomers of alpha subunit are secreted, whereas, oligomers containing the beta subunit are plasma membrane-bound. This gene encodes the beta subunit. Targeted disruption of this gene in mice affects embryonic viability, renal gene expression profiles, and distribution of the membrane-associated alpha subunit in kidney and intestine.

Gene names and symbols associated with Meprin A, beta (MEP1B) ELISA试剂盒

  • meprin A subunit beta (MEP1B) 抗体
  • meprin A subunit beta (LOC100031050) 抗体
  • meprin A subunit beta (mep1b) 抗体
  • meprin A, beta (mep1b) 抗体
  • meprin A subunit beta (LOC100545010) 抗体
  • meprin 1 beta (Mep1b) 抗体
  • meprin A subunit beta (Mep1b) 抗体
  • Mep-1b 抗体
  • MEP1B 抗体
  • si:ch211-191a24.6 抗体
  • zgc:153272 抗体

Protein level used designations for Meprin A, beta (MEP1B) ELISA试剂盒

meprin A, beta , N-benzoyl-L-tyrosyl-p-amino-benzoic acid hydrolase beta , meprin A subunit beta , meprin A subunit beta-like , endopeptidase-2 , meprin B , meprin beta , meprin A beta , N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta , N-benzoyl-L-tyrosyl-p-amino-benzoic acid hydrolase beta subunit , PABA peptide hydrolase , PPH beta

GENE ID SPECIES
421097 Gallus gallus
468515 Pan troglodytes
490497 Canis lupus familiaris
540701 Bos taurus
707036 Macaca mulatta
100031050 Monodelphis domestica
100124942 Xenopus (Silurana) tropicalis
100151009 Danio rerio
100406280 Callithrix jacchus
100461703 Pongo abelii
100474827 Ailuropoda melanoleuca
100516141 Sus scrofa
100545010 Meleagris gallopavo
100563868 Anolis carolinensis
100587715 Nomascus leucogenys
17288 Mus musculus
25727 Rattus norvegicus
4225 Homo sapiens
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