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Phosphomannose isomerase catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate and plays a critical role in maintaining the supply of D-mannose derivatives, which are required for most glycosylation reactions. 再加上，我们可以发Mannose Phosphate Isomerase 抗体 (87) 和 Mannose Phosphate Isomerase 蛋白 (16)和数多这个蛋白质的别的产品。
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This work provides mechanistic evidence by which mannose phosphate isomerase loss induces p53 (显示 TP53 ELISA试剂盒), and identifies mannose phosphate isomerase as a novel regulator of p53 (显示 TP53 ELISA试剂盒) and Warburg metabolism.
Phosphomannose isomerase inhibitors improve N-glycosylation in selected phosphomannomutase-deficient fibroblasts
Data indicate that reduced phosphomannose isomerase (MPI) alters mannose flux in hypomorphic mice.
Phosphomannose isomerase activity and mRNA levels increased at 1 month, and the values in the ileum were lower than in jejunum.
Results suggest that mannose toxicity in phosphomannose isomerase(-/-) embryos is caused by mannose-6-P accumulation, which inhibits glucose metabolism and depletes intracellular ATP.
Data conclude that PMI-null cells can salvage mannose from both endogenous and external glycoconjugates via lysosomal and nonlysosomal degradation pathways.
MPI deficiencies resulted in 50% embryonic lethality by 4 dpf. Multi-systemic abnormalities, including small eyes, dysmorphic jaws, pericardial edema, a small liver and curled tails, occurred in 82% of the surviving larvae.
Phosphomannose isomerase catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate and plays a critical role in maintaining the supply of D-mannose derivatives, which are required for most glycosylation reactions. Mutations in the MPI gene were found in patients with carbohydrate-deficient glycoprotein syndrome, type Ib.
mannose-6- phosphate isomerase
, mannose-6-phosphate isomerase
, phosphomannose isomerase 1
, mannose phosphate isomerase 1
, phosphomannose isomerase
, mannosephosphate isomerase
, mannose phosphate isomerase
, mannose-6-phosphate isomerase-like
, Phosphomannose isomerase