anti-Inhibitor of DNA Binding 4, Dominant Negative Helix-Loop-Helix Protein (ID4) 抗体

ID4 encodes a member of the inhibitor of DNA binding (ID) protein family.

列出全部抗体 基因 基因ID UniProt
小鼠 ID4 ID4 15904 P41139
大鼠 ID4 ID4 291023  
 ID4 ID4 3400 P47928
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antibodies-online.cn销售最多的anti-ID4 抗体

Showing 10 out of 91 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB WB Suggested Anti-ID4 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  293T cell lysate ID4 is strongly supported by BioGPS gene expression data to be expressed in Human HEK293T cells Lanes :  Lane 1: 10ug MDA-MB231 lysateLane 2: 10ug MCF7 lysate   Primary Antibody Dilution :   1:1000    Secondary Antibody :  Anti-rabbit-HRP   Secondary Antibody Dilution :   1:10,000   Gene Name :  ID4   Submitted by :  Maria Teresita Branham. Facultad de Cs Médicas-UNCuyo 100 μL Log in to see 2至3个工作日
$289.00
详细
非结合性 WB WB Suggested Anti-ID4 Antibody Titration:  1.25ug/ml  ELISA Titer:  1:1562500  Positive Control:  HepG2 cell lysate Host:  Rabbit  Target Name:  ID4  Sample Type:  HepG2  Lane A:  Primary Antibody  Lane B:  Primary Antibody + Blocking Peptide  Primary Antibody Concentration:  2.5ug/mL  Peptide Concentration:  2.0ug/mL  Lysate Quantity:  25ug/lane  Gel Concentration:  12% 100 μL Log in to see 2至3个工作日
$229.00
详细
非结合性 IHC, WB Immunohistochemical analysis of ID4 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with t Western blot analysis of ID4 expression in HEK293T (A), HepG2 (B) whole cell lysates. 200 μL Log in to see 13至14个工作日
$487.50
详细
非结合性 ELISA, WB Western blot analysis of extracts from HepG2 cells, using ID4 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2至3个工作日
$302.50
详细
非结合性 WB 100 μg Log in to see 7至9个工作日
$493.17
详细
非结合性 WB 50 μg Log in to see 7至9个工作日
$551.83
详细
非结合性 FACS, IHC (p), WB Western blot analysis of ID4 Antibody (N-term) (ABIN653935) in mouse bladder tissue lysates (35 µg/lane). ID4 (arrow) was detected using the purified polyclonal antibody. ID4 Antibody (N-term) (ABIN653935) IHC analysis in formalin fixed and paraffin embedded bladder followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10至11个工作日
$324.50
详细
非结合性 IHC (p), WB Flow cytometric analysis of 293 cells using ID4 Antibody (N-term) Cat.-No AP52145PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Immunohistochemistry analysis in formalin fixed and paraffin embedded bladder carcinoma reated with ID4 Antibody (N-term) followed which was peroxidase conjugated to the secondary antibody and followed by DAB staining. 0.4 mL Log in to see 6至8个工作日
$390.50
详细
非结合性 IHC (p), IHC, WB Western Blot: ID4 Antibody [NBP1-00882] - Analysis of Id4 (S5) pAb at 1:500 dilution Lane1:A549 whole cell lysate Lane2:Raw264.7 whole cell lysate Lane3:H9C2 whole cell lysate Western Blot: ID4 Antibody [NBP1-00882] - Western blot (WB) analysis of ID4 (S5) antibody in extracts from HepG2 cells 0.1 mL Log in to see 7至9个工作日
$490.19
详细
非结合性 ELISA, IHC, IHC (p), WB Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 7至9个工作日
$484.00
详细

引用最多的anti-ID4 抗体

  1. Human Polyclonal ID4 Primary Antibody for WB - ABIN516801 : Oatley, Kaucher, Racicot, Oatley: Inhibitor of DNA binding 4 is expressed selectively by single spermatogonia in the male germline and regulates the self-renewal of spermatogonial stem cells in mice. in Biology of reproduction 2011 (PubMed)

  2. Human Polyclonal ID4 Primary Antibody for IHC (p), IHC - ABIN314651 : Vincent, Li, Lee, Liu, Etter, Diaz-Perez, Taylor, Gkountela, Lindgren, Clark: Single cell analysis facilitates staging of Blimp1-dependent primordial germ cells derived from mouse embryonic stem cells. in PLoS ONE 2011 (PubMed)

  3. Dog (Canine) Polyclonal ID4 Primary Antibody for WB - ABIN2780374 : Yu, Liu, Vandeusen, Becknell, Dai, Wu, Raval, Liu, Ding, Mao, Liu, Smith, Lee, Rassenti, Marcucci, Byrd, Caligiuri, Plass: Global assessment of promoter methylation in a mouse model of cancer identifies ID4 as a putative tumor-suppressor gene in human leukemia. in Nature genetics 2005 (PubMed)
    Show all 2 Pubmed References

更多抗ID4的相互作用对抗体

Mouse (Murine) Inhibitor of DNA Binding 4, Dominant Negative Helix-Loop-Helix Protein (ID4) interaction partners

  1. ID4 has a role in stem cell or progenitor capacity in spermatogonia and dictates the interface of transition between the different functional states

  2. results indicate that Id4 marks spermatogonial stem cells in the mouse testis.

  3. ID4 marks a stem cell-enriched subset of the mammary basal cell population. ID4 maintains the mammary stem cell pool by suppressing key factors required for luminal differentiation.

  4. Id4 regulates NKX3.1, Sox9 and PTEN.

  5. Id4 is a novel regulator of estrogen signaling, where Id4 restrains ERalpha (显示 ESR1 抗体) expression in the basal and luminal cellular compartments of the mammary gland and regulates estrogen biosynthesis in the ovary

  6. High expression levels of Id1 (显示 ID1 抗体)-4 proteins may play important roles in regulating retinal progenitor cell proliferation and differentiation.

  7. CpG-rich islands within the Id2 and Id4 genes were bound by PRMT5 (显示 PRMT5 抗体) and were hypomethylated in PRMT5 (显示 PRMT5 抗体)-deficient cells, suggesting that PRMT5 (显示 PRMT5 抗体) plays a role in gene silencing during glial cell

  8. ID4 promotes mammary gland development by suppressing p38MAPK (显示 MAPK14 抗体) activity.

  9. Study confirms the importance of the silencing of ID4 in murine and human CLL pathogenesis.

  10. Id4 was identified as a key transcription factors enriched in the early phase of differentiation and affecting the differentiation of both osteoblasts and adipocyte cell types.

Zebrafish Inhibitor of DNA Binding 4, Dominant Negative Helix-Loop-Helix Protein (ID4) interaction partners

  1. id4 appears to control the number of endocardial cells that contribute to the AV valves by regulating Wnt (显示 WNT2 抗体) signaling in the developing AVC endocardium

Human Inhibitor of DNA Binding 4, Dominant Negative Helix-Loop-Helix Protein (ID4) interaction partners

  1. These findings indicate that ID4 acts as a tumour suppressor in myeloid malignancies, and ID4 methylation is a potential biomarker in predicting disease progression and treatment outcome.

  2. results highlight a key role for MALAT1 in control of VEGFA (显示 VEGFA 抗体) isoforms expression in breast cancer cells expressing gain-of-function mutant p53 (显示 TP53 抗体) and ID4 proteins.

  3. Study demonstrates that ID4, can promote p53 (显示 TP53 抗体)- dependent apoptosis and senescence in prostate cancer cells by specifically modifying the acetylation of p53 (显示 TP53 抗体), which increases its transcriptional activity and promotes the expression of pro-apoptotic and cell cycle regulatory genes.

  4. The cellular uptake of inhibitor of DNA binding 4 protein (ID4) resulted in increased apoptosis, decreased proliferation and colony formation.

  5. Several lines of evidence suggest ID4 may suppress BRCA1 function in basal-like breast cancer (BLBC) and in doing so, define a subset of BLBC patients who may respond to therapies traditionally used in BRCA1-mutant cancers. This review highlights recent advances in our understanding of the requirement for ID4 in mammary lineage commitment and the role for ID4 in BLBC.

  6. The expression of Id4 protein was up-regulated in tumor tissues from hepatocellular carcinoma (HCC (显示 FAM126A 抗体)) patients, and overexpression of Id4 promoted HCC (显示 FAM126A 抗体) cell proliferation, clonogenicity in vitro, and tumorigenicity in vivo.

  7. ID4 selectively regulates AR activity through direct interaction with FKBP52 (显示 FKBP4 抗体).

  8. High ID4 expression is associated with basal breast cancer.

  9. A cell-autonomous positive-signaling circuit is associated with the PDGFB (显示 PDGFB 抗体)-NO-ID4-regulatory axis in glioblastoma cells.

  10. ID4 expression induces AR expression in PC3 (显示 PCSK1 抗体) cells, which generally lack AR. ID4 expression increased apoptosis and decreased cell proliferation and invasion.

ID4 抗原简介

蛋白简介

This gene encodes a member of the inhibitor of DNA binding (ID) protein family. These proteins are basic helix-loop-helix transcription factors which can act as tumor suppressors but lack DNA binding activity. Consequently, the activity of the encoded protein depends on the protein binding partner.

Gene names and symbols associated with ID4

  • inhibitor of DNA binding 4 (Id4) 抗体
  • inhibitor of DNA binding 4, HLH protein (Id4) 抗体
  • inhibitor of DNA binding 4 (id4) 抗体
  • inhibitor of DNA binding 4, HLH protein S homeolog (id4.S) 抗体
  • inhibitor of DNA binding 4, HLH protein (ID4) 抗体
  • bhlhb27 抗体
  • cb547 抗体
  • fb77d04 抗体
  • id4 抗体
  • id4a 抗体
  • IDB4 抗体
  • sb:cb547 抗体
  • wu:fb77d04 抗体
  • zgc:123214 抗体

Protein level used designations for ID4

DNA-binding protein inhibitor ID-4 , inhibitor of DNA binding 4 a , class B basic helix-loop-helix protein 27

GENE ID SPECIES
15904 Mus musculus
291023 Rattus norvegicus
664761 Danio rerio
380396 Xenopus laevis
374150 Gallus gallus
3400 Homo sapiens
610666 Canis lupus familiaris
100144508 Sus scrofa
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