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The protein encoded by GPD1L catalyzes the conversion of sn-glycerol 3-phosphate to glycerone phosphate. 再加上，我们可以发GPD1L 抗体 (48) 和 GPD1L 试剂盒 (4)和数多这个蛋白质的别的产品。
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Then bioinformatic analysis identified potential target sites of the miR (显示 MLXIP 蛋白)-181a located in the 3' untranslated region of GPD1L. Increased GPD1L and decreased miRNA-181a were observed in tissues from osteoarthritis patients. Our results demonstrated that miR (显示 MLXIP 蛋白)-181a may play an important role in the pathogenesis of Osteoarthritis through targeting GPD1L and regulating chondrocyte apoptosis.
In a nonreferred nationwide Danish cohort of SIDS (显示 IDS 蛋白) cases, up to 5/66 (7.5%) of SIDS (显示 IDS 蛋白) cases can be explained by genetic variants in the sodium channel complex genes.
The results of real-time PCR showed that, compared with the paired normal tissues, mRNA levels of GPD1L were decreased significantly in head and neck squamous cell carcinoma.
Common variations in or near CASQ2 (显示 CASQ2 蛋白), GPD1L, and NOS1AP (显示 NOS1AP 蛋白) are associated with increased risk of sudden cardiac death in patients with coronary artery disease
hypoxia-induced miR (显示 MLXIP 蛋白)-210 represses GPD1L, contributing to suppression of prolyl hydroxylases activity, and increases of HIF-1alpha (显示 HIF1A 蛋白) protein levels.
mutations in GPD1-L as a pathogenic cause for a small subset of sudden infant death syndrome via a secondary loss-of-function mechanism
A GPD1-L mutation decreases SCN5A (显示 SCN5A 蛋白) surface membrane expression, reduces inward Na+ current, and causes Brugada syndrome
No non-synonymous mutations were found, indicating that GPD1L does not appear to be a major cause of Brugada syndrome in a Japanese population.
GPD1L links redox state to cardiac excitability by PKC (显示 PRRT2 蛋白)-dependent phosphorylation of the sodium channel SCN5A (显示 SCN5A 蛋白).
Mutations of GPD1-L may downregulate Na(v)1.5 by altering the oxidized to reduced NAD(H) balance.
The protein encoded by this gene catalyzes the conversion of sn-glycerol 3-phosphate to glycerone phosphate. The encoded protein is found in the cytoplasm, associated with the plasma membrane, where it binds the sodium channel, voltage-gated, type V, alpha subunit (SCN5A). Defects in this gene are a cause of Brugada syndrome type 2 (BRS2) as well as sudden infant death syndrome (SIDS).
glycerol-3-phosphate dehydrogenase 1-like protein
, glycerol-3-phosphate dehydrogenase 1-like
, glycerol-3-phosphate dehydrogenase 1-like protein-like